Adrenaline Flashcards
1
Q
Presentation of Adrenaline
A
1mg in 1ml amp
(1:1,000)
1mg in 10ml amp
(1:10,000)
2
Q
Pharmacology of Adrenaline
A
Naturally occurring Alpha and Beta-adrenergic stimulant
3
Q
Pharmacology of Adrenaline (actions)
A
Increases
- Pulse rate by increasing S.A. node firing rate (Beta 1)
- Conduction velocity through the A.V. node (Beta 1)
- Myocardial contractility (Beta 1)
- Irritability of the ventricles (Beta 1)
Causes
- Bronchodilatation (Beta 2)
- Peripheral vasoconstriction (Alpha)
4
Q
Metabolism of Adrenaline
A
By monoamine oxidase and other enzymes in blood, liver, and around nerve endings
Excreted by the kidneys
5
Q
Adrenaline Indications
A
- Asystole
- Persistent VF or unconscious pulseless VT
- EMD/PEA
- Anaphylactic reactions
- Severe Asthma
- Inadequate perfusion (Cardiogenic)
- Inadequate perfusion (Non Cardiogenic - Non Hypovolamic)
- Croup or suspected Croup
- Unconscious Asthma with no recordable BP
Bradycardia with poor perfusion
6
Q
Adrenaline Contraindications
A
Hypovolaemic shock without adequate fluid replacement
7
Q
Adrenaline Precautions
A
- Beta-blockers
- Elderly pt’s
- Cardiovascular disease
- Mao inhibitors
8
Q
Route of Administration of Adrenaline
A
IM IV IV infusion IO ET Nebuliser
9
Q
Side Effects of Adrenaline
A
- Pupillary dilatation
- Arrhythmias (ventricular/supraventricular)
- Sinus tachycardia
- Hypertension
- Feeling of anxiety/palpitations
- May increase size of MI
10
Q
Effects of Adrenaline
A
IV
Onset: 30sec
Peak: 3-5min
Duration: 5-10min
IM
Onset: 30-90sec
Peak: 4-10min
Duration: 5-10min
