Ceftriaxone

Question 1

Presentation of Ceftriaxone

Answer 1

1g sterile powder in vial

Question 2

Pharmacology of Ceftriaxone

Answer 2

Cephalosporin antibiotic

Question 3

Metabolism of Ceftriaxone

Answer 3

Excreted unchanged in urine and in bile

Question 4

Ceftriaxone Indications

Answer 4

Suspected Meningicoccal Septicaemia

Severe Sepsis (consult only)

Question 5

Ceftriaxone Contraindications

Answer 5

Allergy to Cephalosporin antibiotics

Question 6

Ceftriaxone Precautions

Answer 6

Allergy to Penicillin antibiotics

Question 7

Route of Administration of Ceftriaxone

Answer 7

IV (preferred)

IM (if IV access unable to be obtained)

Question 8

Side Effects of Ceftriaxone

Answer 8

Nausea and Vomiting

Skin rash

Question 9

Ceftriaxone Special Notes

Answer 9

Usual Dose:
Adult 1g
Child 50mg/kg

Ceftriaxone IV must be made up to 10ml using sterile water and dose administered over 2min

Ceftriaxone IM must be made up to 4ml using 1% Lignocaine and dose administered in lateral upper thigh