Lignocaine 1% (intraosseous)

Question 1

Presentation

Answer 1

50mg in 50ml amp 1%

Question 2

Pharmacology of Lignocaine

Answer 2

Local anaesthetic agent

Question 3

Pharmacology of Lignocaine (actions)

Answer 3

Prevents initiation and transmission of nerve impulses (local anaesthesia)

Question 4

Metabolism of Lignocaine

Answer 4

By the liver

Excreted unchanged by the kidneys

Question 5

Lignocaine Indications

Answer 5

Intraosseous Administration

To reduce the pain of the intraosseous drug and fluid administration in the responsive patient

Question 6

Lignocaine Contraindications

Answer 6

Known hypersensitivity

Question 7

Lignocaine Precautions

Answer 7

Intraosseous admin (1%)

• Hypotension and poor perfusion
• Chronic left ventricular failure
• Liver disease

Question 8

Route of Administration of Lignocaine

Answer 8

Intraosseous

Question 9

Side Effects of Lignocaine

Answer 9

Intraosseous administration
CNS effects (common)
- drowsiness
- disorientation
- decreased hearing
- blurred vision
- change or slurring of speech
- twitching and aggitation
- convulsions

CV effects (uncommon)

• hypotension
• bradycardia
• sinus arrest
• A.V. block

Respiratory (uncommon)

• difficulty in breathing
• respiratory arrest

Question 10

Effects of Lignocaine

Answer 10

IO
Onset: 1-4min
Peak: 5-10min
Duration: 20min