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Pathopharm > Principles of Neuropharmacology > Flashcards

Principles of Neuropharmacology Flashcards

1
Q

What is neuropharmacology

A

How drugs effect nerve cells

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2
Q

What is an action potentil

A

The stimulus that has the information

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3
Q

What happens to the neurotransmitters after the action potential

A

They are released

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4
Q

What happens after the neurotransmitters are released

A

They bind to receptors

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5
Q

What happens to the neurotransmitters that were released but didn’t binid to respeptors

A

They are reuptaked or degraded

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6
Q

What is reuptake

A

When extra neurotransmitters are absorbed back into the nerve cellWh

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7
Q

What is degradation

A

When extra neurotransmitters are broken down

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8
Q

What type of drugs are SSRIs (antidepressants) in terms of reuptake

A

They inhibit reuptake

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9
Q

What do reuptake ingibitor drugs cause

A

INCREASED stimulation and PROLONGED stimulation

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10
Q

What is the autonomic nervous system reffered to

A

The involuntary nervous system

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11
Q

Is the autonomic nervous system self-governing and automatic

A

Yes and yes

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12
Q

What does the autonomic nervous system regulate

A

HR, BP, EYES

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13
Q

What type of nerve fibers does the ANS have

A

ADRENERGIC and CHOLINERGIC

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14
Q

What are the sympathetic receptors

A

Adrenergic

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15
Q

What is the neurotransmitter for adrenergic receptors

A

Norepinephrine (NE)

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16
Q

What does bronchodilation do

A

It opens the air ways to allow more O2

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17
Q

Which receptors have alpha and beta receptors

A

Adrenergic

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18
Q

Is epinephrine selective

A

No

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19
Q

What are some uses of Epi

A

ANAPHYLAXIS, ASTMATICS, SHOCK, cardiac ARREST

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20
Q

Does epi have a slow or fast onset

A

Fast

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21
Q

What are the side effects/ adverse reactios to epi

A

Cardiac DYSRHYTHMIAS, PALPITATIONS, TACHYCARDIA, HYPERTENTION, DISSY, HEADACHE, AGITATION, HYPERGLYCEMIA

22
Q

What type of receptors does the PNS have

A

Cholinergic

23
Q

What is the neurotransmitter for cholinergic receptors

A

Acetylcholine (Ach)

24
Q

What is mydriasis

A

Dialation of the pupils

25
Q

What is miosi

A

Constriction of the pupils

26
Q

What will an adrenergic blocker do to the airway

A

Broncoconstriction

27
Q

What does a chronotropic drug do

A

It effects the heart RATE

28
Q

What does a dromotropic drug do

A

It effects the CONDUCTION of the heart

29
Q

What does a inotropic drug do

A

It affects the CONTRACTION of the heart

30
Q

Why is it important to vasoconstrict when using the sympathic nervous system

A

It increases the BP which forces blood to the ORGANS

31
Q

What are adrenergic drugs

A

They mimc the SYMPATHETIC nervous system

32
Q

What are sympathomimetic drugs

A

They mimic the SYMPATHETIC nervous system

33
Q

What are adrenergic blockers

A

They inhibit the SYMPATHETIC nervous system

34
Q

What are sympatholytic drugs

A

They inhibit the SYMPATHETIC nervous system

35
Q

What type of effect do sympatholytic drugs have

A

A cholinergic effect

36
Q

What are cholinergics drugs

A

They mimic the PARASYMPATHETIC nervous system

37
Q

What are parasympathomimetics

A

They mimic the PARASYMPATHETIC nervous system

38
Q

What are anticholinergics

A

They inhibit the PARASYMPATHETIC nervous system

39
Q

What are parasympatholytics

A

They inhibit the PARASYMPATHETIC nervous system

40
Q

Can medications be more focused on one system (nervous system)

A

Yes

41
Q

What is another name for a muscarinic

A

Cholinergic agonist

42
Q

What system does bethanechol focus on

A

The bladder

43
Q

When is bethanechol used

A

After surgeries to make you PEE

44
Q

What type of drug is bethanechol

A

A CHOLINERGIC AGONIST

45
Q

What type of effects do muchrooms have

A

A cholinergic effect (slows everything down)

46
Q

Your pt is on a cholinergic agonist drug, should they have mushrooms

A

No, it could cause cardiovascular collapse

47
Q

What type of drug is atropine

A

A cholinergic antagonist

48
Q

What is the therapeutic use of atropine

A

A PREANESTETIC to prevent a dangerous drop in HR

49
Q

What is the antibote to muscarinic poisoning

A

Atropine

50
Q

What happens to the body in a sympathetic response
Eyes:
HR:
BP:
RR:
Lungs:
Blood vessels:
GI system:
Detrusor muscle:
Urinary spnicter:
Blood sugar:

A

Eyes: DIALATE
HR: INCREASES
BP: INCREASES
RR: INCREASES
Lungs: broncoDIALATION
Blood vessels: vasoCONSTRICTION
GI system: SLOW
Detrusor muscle: RELAXES
Urinary spnicter: CONTRACTS
Blood sugar: INCREASES

51
Q

What happens to the body in a parasympathetic response
Eyes:
HR:
BP:
RR:
Lungs:
Blood vessels:
GI system:
Detrusor muscle:
Urinary sphincter:
Blood sugar:

A

Eyes: CONSTRICTION
HR: DECREASES
BP: DECREASES
RR: DECREASES
Lungs: broncoCONSTRICTION
Blood vessels: vasoDIALATION
GI system: SPEEDS UP
Detrusor muscle: CONTRACTS
Urinary spnicter: RELAXES
Blood sugar: DECREASES

52
Q
A

Pathopharm (8 decks)

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