Principles of Neuropharmacology Flashcards

1
Q

What is neuropharmacology

A

How drugs effect nerve cells

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2
Q

What is an action potentil

A

The stimulus that has the information

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3
Q

What happens to the neurotransmitters after the action potential

A

They are released

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4
Q

What happens after the neurotransmitters are released

A

They bind to receptors

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5
Q

What happens to the neurotransmitters that were released but didn’t binid to respeptors

A

They are reuptaked or degraded

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6
Q

What is reuptake

A

When extra neurotransmitters are absorbed back into the nerve cellWh

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7
Q

What is degradation

A

When extra neurotransmitters are broken down

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8
Q

What type of drugs are SSRIs (antidepressants) in terms of reuptake

A

They inhibit reuptake

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9
Q

What do reuptake ingibitor drugs cause

A

INCREASED stimulation and PROLONGED stimulation

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10
Q

What is the autonomic nervous system reffered to

A

The involuntary nervous system

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11
Q

Is the autonomic nervous system self-governing and automatic

A

Yes and yes

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12
Q

What does the autonomic nervous system regulate

A

HR, BP, EYES

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13
Q

What type of nerve fibers does the ANS have

A

ADRENERGIC and CHOLINERGIC

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14
Q

What are the sympathetic receptors

A

Adrenergic

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15
Q

What is the neurotransmitter for adrenergic receptors

A

Norepinephrine (NE)

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16
Q

What does bronchodilation do

A

It opens the air ways to allow more O2

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17
Q

Which receptors have alpha and beta receptors

A

Adrenergic

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18
Q

Is epinephrine selective

A

No

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19
Q

What are some uses of Epi

A

ANAPHYLAXIS, ASTMATICS, SHOCK, cardiac ARREST

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20
Q

Does epi have a slow or fast onset

A

Fast

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21
Q

What are the side effects/ adverse reactios to epi

A

Cardiac DYSRHYTHMIAS, PALPITATIONS, TACHYCARDIA, HYPERTENTION, DISSY, HEADACHE, AGITATION, HYPERGLYCEMIA

22
Q

What type of receptors does the PNS have

A

Cholinergic

23
Q

What is the neurotransmitter for cholinergic receptors

A

Acetylcholine (Ach)

24
Q

What is mydriasis

A

Dialation of the pupils

25
What is miosi
Constriction of the pupils
26
What will an adrenergic blocker do to the airway
Broncoconstriction
27
What does a chronotropic drug do
It effects the heart RATE
28
What does a dromotropic drug do
It effects the CONDUCTION of the heart
29
What does a inotropic drug do
It affects the CONTRACTION of the heart
30
Why is it important to vasoconstrict when using the sympathic nervous system
It increases the BP which forces blood to the ORGANS
31
What are adrenergic drugs
They mimc the SYMPATHETIC nervous system
32
What are sympathomimetic drugs
They mimic the SYMPATHETIC nervous system
33
What are adrenergic blockers
They inhibit the SYMPATHETIC nervous system
34
What are sympatholytic drugs
They inhibit the SYMPATHETIC nervous system
35
What type of effect do sympatholytic drugs have
A cholinergic effect
36
What are cholinergics drugs
They mimic the PARASYMPATHETIC nervous system
37
What are parasympathomimetics
They mimic the PARASYMPATHETIC nervous system
38
What are anticholinergics
They inhibit the PARASYMPATHETIC nervous system
39
What are parasympatholytics
They inhibit the PARASYMPATHETIC nervous system
40
Can medications be more focused on one system (nervous system)
Yes
41
What is another name for a muscarinic
Cholinergic agonist
42
What system does bethanechol focus on
The bladder
43
When is bethanechol used
After surgeries to make you PEE
44
What type of drug is bethanechol
A CHOLINERGIC AGONIST
45
What type of effects do muchrooms have
A cholinergic effect (slows everything down)
46
Your pt is on a cholinergic agonist drug, should they have mushrooms
No, it could cause cardiovascular collapse
47
What type of drug is atropine
A cholinergic antagonist
48
What is the therapeutic use of atropine
A PREANESTETIC to prevent a dangerous drop in HR
49
What is the antibote to muscarinic poisoning
Atropine
50
What happens to the body in a sympathetic response Eyes: HR: BP: RR: Lungs: Blood vessels: GI system: Detrusor muscle: Urinary spnicter: Blood sugar:
Eyes: DIALATE HR: INCREASES BP: INCREASES RR: INCREASES Lungs: broncoDIALATION Blood vessels: vasoCONSTRICTION GI system: SLOW Detrusor muscle: RELAXES Urinary spnicter: CONTRACTS Blood sugar: INCREASES
51
What happens to the body in a parasympathetic response Eyes: HR: BP: RR: Lungs: Blood vessels: GI system: Detrusor muscle: Urinary sphincter: Blood sugar:
Eyes: CONSTRICTION HR: DECREASES BP: DECREASES RR: DECREASES Lungs: broncoCONSTRICTION Blood vessels: vasoDIALATION GI system: SPEEDS UP Detrusor muscle: CONTRACTS Urinary spnicter: RELAXES Blood sugar: DECREASES
52