Acid-Base Balance Flashcards
What is the fange of a pH scale
0-14
What are the pH numbers a factor of
10
What is the normal body fluid pH
7.35-7.45
What range can death happen related pH
6.8-7.8
Are there more or less hydrogen ions in acidosis
More
Are there more or less hydrogen ions in alkalosis
Less
What does acidosis do to K
H ions accumulate in the ECF (blood), K shift OUT of the cell and into the ECF (blood)
What does alkalosis do to K
H ions accumulate in the ICF, K shifts into the cell
What responses to pH changes immediately
Buffer pairs
What is the quickest way to control serium pH
The respiratory system
How does the respiratory system change pH
Alter CO2 (carbonic acid) in the body by changing the respiratory rate
What is the most significant control mechanism of pH
The kidneys can modify the excretion rate of acids and the production and absorption of bicarbonate ions
Are the kidney fast or slow to changing the pH
slow
What are acids
End products of protein, carb, and fat metabolism (waste)
What must have to the H ion to maintain the body’s normal pH
It must be NEUTRALIZED or EXCREATED
What three things are invovled in the regulation of acid and base balance
RBCs, lungs, kidneys
What is a buffer
Combination of a weak acid and alkaline salt
What do buffers do
Either collects or releases H ion
What is the top buffer system
Sodium bicarbonate-carbonic acid system
What is the ratio of bicarbonate to carbonic acid
20:1
If the amount of bicarb decreases what happens to the pH
decreases
What is it called if the amount of bicarb decreases making the pH decrease but then the amount of carbonic acid also decreases to stabilize the pH
Compensation
What does the lab value of pH mean
acid-base balance
What does the lab value of PaCO2
Lungs
What does the lab value of HCO3
Kidneys
What does the lab value of PaO2 mean
Oxygenation of blood
What is acidosis
EXCESS H ions, DECREASE in pH
What is alkalosis
DEFICT of H ions, INCREASE in pH
What is respiratory acidosis
Increase in carbon dioxide levels
What is metabolic acidosis
Decrease in bicarb ions
What is respiratory alkalosis
Decrease in carbon dioxide levels
What is metabolic alkalosis
Loss of H ions through kidneys/GI tract
What is the normal range of bicarb (HCO3)
22-26
What does it mean if HCO3 is less than 22
Metabolic acidosis
What does it mean if HCO3 is greater than 26
Metabolic alkalosis
What is the normal range of carbon dioxide (PaCO2)
35-45
What does it mean if PaCO2 is less than 35
Respiratory alkalosis
What does it mean if PaCO2 is greater than 45
Respiratory acidosis
What causes respiratory acidosis
Slow shallow breathing
What causes respiratory alkalosis
Hyperventilation
How do the kidneys compensate for respiratory acidosis
Excrete more H ions and reabsorb more bicarb
How do the kidneys compensate for respiratory alkalosis
Excrete less H ions and reabsorb less bicarb
What causes metabolic acidosis
Shock, renal failure, diarrhea, diabetic ketoacidosis
How do the lungs compensate for metabolic acidosis
Rapid deep breathes
What causes metabolic alkalosis
vomiting, excessive antacid intake
How do the lungs compensate for metabolic alkalosis
Slow shallow breathes
What are the acute problems that can cause respiratory acidosis
airway obstruction, drugs that depress the respiratory control center
What are the chronic problems that can cause respiratory acidosis
COPD
What are the syptoms of respiratory acidosis
dizzy, warm flushed skin, dyspnea, tachycardic
What is the treatment of respiratory acidosis
Establish airway, treat cause, hyperventilate the patient
What are the specific causes of metabolic acidosis
diarrhea (loss of bicarb), renal disease or failure (dialysis), don’t excreat acids or produce bicarb
What are the symptoms of metabolic acidosis
altered breathing, weakness, hyperkalemia, reduced cardiac output
What is the treament for metabolic acidosis
Treat the cause, give sodium bicarb
What are the effects of acidosis
Headache, weak, confused, coma, death
What is the compensation for acidosis
Deep rapid breathing, acidic peeing
What are the spesifc causes of respiratory alkalosis
Hyperventilation, anxiety, overdoes of ASPRIN, head injuries, brain stem tumor
What are the symptoms of respiratory alkalosis
Rapid shallow breathing, numbness, sweating, dizzy
What is the treament of respiratory alkalosis
Treat the cause, usally fever
What are the spesific causes of metabolic alkalosis
Increase in bicarb, loss of acid from stomach, hypokalemia, too many antacids
What are the symptoms of metabolic alkalosis
irritability, confusion, tingling, hyperactive reflexes
What is the treatments of metabolic alkalosis
Treat the cause, don’t suction, anti comit meds
What are the treatments of imbalances
Treat CAUSE, corrective FLUIDS, add BICARB, DIET (avoid potassium)
What is compensation
Limited and short term change in buffers, respiration, or renal function to balance, does NOT fix the cause
What happens when there is decompensation
EMERGENCY, problems are SEVERE, MORE issues, FAILURE to compensate
What will the pH level be if it is compensated
Normal