Antibiotics Pt. 3 & Anti-fungals Flashcards
What is TB caused by
Mycobacterium
What is TB characterized by
granulomas in the lungs
What is the promary site of TB
LUngs
How is TB spread
Airborne
Can people have non-active TB
Yes because it can be dormant or be walled off
What are the first line drugs for TB
Isoniazid (INH) & Rifampin
Why is treating TB difficult
Drug REGIMEN, COMPLIANCE for 2 years
What is the drug choice for TB
Isoniazid
What does isoniazid effect
Liver, “slow acetylators”
What are the adverse effect of isoniazid
Neuro/hepatotoxicity
What are the adverse effects of rigampin
Discoloration of body fluids, ineffectivness of oral contraceptives
What should you assess when your pt is on an antiTB med
Liver function
What are fungi
Yeasts and mold
What are fungal infections know as
mycoses
What are dermatophytes
Fungi that cause integumentary infections
What are yeasts
single-cell
What are molds
multi-cellular
What type of mycotic infections are life threatening especially for immunocompromised hosts
Systemic
What is candida albicans
Most COMMON fungal infection usally after antibiotic use, trush
What type of drugs are amphotericin B, fluconazole, and nystatin
Antifungal drugs
What is amphotericin B used for
Severe systemic fungla infectionsha
What is fluconaole used for
Fungal meningitis
What are the adverse effects of amphotericin B
Cardiac, neuro/nephro toxicity
What are some interventions of amphotericin B
premeds, slow infusion