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primary species cram cards Flashcards

1
Q

rabbit diseases

Cryptosporidiosis

A

Cryptosporidium cuniculus

weanling rabbits most affected

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2
Q

pig diseases

swine influenza

A

orthomyxovirus

high morbidity (100%) but low mortality

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3
Q

pig diseases

Things to know about Clostridial enteritis

A

12hrs-4wks old (peaks at 3 days)

persistent diarrhea, clear fluid with necrotic debris

can die within 4-8 hours after exposure

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4
Q

rabbit diseases

things to know about Encephalitozoonosis

A

Encephalitozoon cuniculi

affects multiple species

brain and kidney, granulomas

microsporidian

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5
Q

in mice the MHC allele is located on what chromosome?

A

17

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6
Q

mouse diseases

4 important things about Murine Pneumonia virus

A

paramyxovirus

co-infection with Pneumocystis common

natural infection is subclinical in immunocompetent mice, dyspnea, listlesness, wasting in immunodeficient

self limiting in immunocompetent, and persistent in immunodeficient

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7
Q

rat models

BUF (Buffalo) rat is a model for

A

spontaneous autoimmune thyroiditis

transplantable Morris hepatoma

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8
Q

NHP diseases

things to know about Hepatitis A

A

Picornaviridae

chimps and cynos and owl monkeys susceptible but no CS

fecal-oral

zoonotic

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9
Q

rat model

Nude rat is a model for

A

t cell deficiency

autosomal recessive

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10
Q

rabbit biology

unique characteristics of the urinary system

A

unipapillate

can separate the tubutles iwth basement membrane intact

ectopic glomeruli are normal

CCMAMP

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11
Q

pig diseases

things to know about Colibacillosis

A

caused by pathogenic Escherichia coli

very young- hours old through post weaning

hypersecretory diarrhea

Edema disease

serious in younger pigs

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12
Q

rat diseases

2 things to know about Mycoplasma haemomuris

A

1- transmitted by Polyplax spinulosa

2) normally latent infection unless activated by immunosuppression or splenectomy

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13
Q

mouse diseases

name the three flagellated protozoans found in mice

A

Giardia muris,

Spironucleus muris,

Tritrichomonas muris

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14
Q

rat diseases

what Pneumocystis spp infects rats

A

Pneumocystis cainii

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15
Q

pig biology

describe the anatomic location of the thyroid and thymus

A

thyroid and thymus are inverted in their location

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16
Q

what stain is used to diagnose amyloidosis

A

Congo red

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17
Q

mouse diseases

what is the most common cestode found in mice

A

Rodentolepis nana or the dwarf tapeworm

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18
Q

pig biology

placentation in swine

A

diffuse epitheliochorial

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19
Q

NHP diseases

things to know about Cercopithecine herpesvirus 2

A

natural host= African green monkey

AKA Simian agent 8, used as safer antigen for B virus tests

alpha herpes virus, simplex virus

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20
Q

NHP diseases

things to know about mollusceum contagiosum

A

chimpanzees

waxy small tumors on face and extremities

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21
Q

NHP diseases

things to know about Streptococcus pneumoniae

A

in chimps starts as upper respirtory disease

think meningitis

fibrinopurulent leptomeningitis

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22
Q

list mouse caging material from most expensive to least

A

polyethermide, polycarbonate, polypropelene, polystyrene, polyethylene

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23
Q

which mouse species are resistant to dystrophic mineralization?

A

C57BL/6

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24
Q

mouse diseases

3 important things about Rodentolepeis nana

A

1- direct or indirect lifecycle

2- adults have scolex with 4 suckers and 20-27 rostellar hooks, eggs ahve 6 polar filaments

3- eggs do not survive well outside host

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25
pig diseases Things to know about the swine whipworm
Trichuris suis diarrhea, dehydration double operculated eggs 2-6mo pigs
26
NHP diseases which pentastomes are found in NW
Porocephalus
27
rabbit diseases things to know about Tyzzers disease
Clostritium piliforme 3-8 wk old rabbits
28
mouse diseases 6 important things about Helicobacter
1- chronic active hepatitis= H. hepaticus in immune disregulated mice 2- A/J are susceptible, BL6 are resistant 3- silver stain 4- TX by Amoxicillin, Metronidazole, Bismith for 2 weeks 5- other species are H. muridarum, rappini, rodentium, typhlonius, pylori, billus 6- transplacental transmission possible, also recommend foster at less than 24 hours
29
rat model Gunn rat is a model for
jaundice kernicterus autosomal recessive
30
mouse diseases 5 important things about Citrobacter
1. rectal prolapse 2. saphyrophyte 3- DBA,NIH swiss, C57BL are resistant, A/J, C3H are susceptable 4- mucosal hyperplasia of descending colon, pathognomonic 5- causes transmissible colonic hyperplasia
31
NHP biology common marmosets are more susceptible to which diseases and why?
bacterial limited MHC class II
32
NHP diseases things to know about Retroperitoneal fibromatosis associated herpesvirus
gammaherpesvirus, rhadinovirus immunosuppression with SRV leads to retroperitoneal fibromatosis lesions
33
mouse diseases 4 important things about Syphacia
1- 11-15 day life cycle 2- diagnose by tape test 3- eggs are flattened on one side with pointed ends 4- infection is subclinical
34
NHP diseases what is the most important intestinal parasite in NW NHP
Prosthenorchis elegans nematode cockroaches spred lives in cecum or colon
35
rat model LOU/C rat is a model for
myeloma production of IgG autoantibody
36
rabbit diseases lumbar fracture
L6-L7
37
pig diseases things to know about Balantidium coli
zoonotic ciliated protozoan cecum and anterior colon
38
mouse diseases 5 important things about Giardia muris
1- infects duodenum of young and adult mice 2- does NOT cause diarrhea 3- moves in rolling/tumbling motion 4- elipsoidal cysts with 4 nuclei "monkey face" 5- C3H, SJL, CBA are susceptible while DBA/2, BALB/c and C57BL/6 are resistant
39
what mouse strains have a low natural prevalance of mammary tumors?
BALB/c C57BL AKR
40
rat diseases 2 things about rotaviruses in rats
most likely human in origin only see clinical signs of diarrhea up to 12 days old then are resistant
41
rat diseases What rat strain is most susceptible to Nephrocalcinosis
female BDIX rats
42
NHP diseases things to know about Helicobacter
H. pylori persistent lymphocytic gastritis OW and NW
43
rat model WF (wistar furth)
mononuclear cell leukemia
44
which mouse species are susceptible to dystrophic mineralization?
DBA/2 (epicardium) BALB/c (epicardium) C3H (myocardium)
45
describe the Bruce effect
strange male pheremones prevent implantation
46
dog models which dog breed is a model for Wilson's disease
Bedlington terriers
47
NHP diseases things to know about Papiine herpesvirus 2
natural host=baboons used as safter antigen in B virus tests alpha herpes virus, simplexvirus
48
rat diseases list 4 things to know about pneumonia virus of mice
paramyxoviridae no clinical disease signs wide host range will burn out if no new susceptibles
49
what does (.) stand for in mouse nomenclature
congenic
50
Animal model Male pattern baldness
Macaca arctoides stump tailed macaque
51
Mycoptes musculinus
52
NHP diseases things to know about Simian Foamy virus
retrovirus, spumavirus high prevalence zoonotic, but no clinical signs seen
53
Pig diseases things to know about Glassers disease
Haemophilus parasuis neuro, arthritis, respiratory 3wk-4mo fibrinous pleuritis
54
describe the difference between the male and female submaxillary salivary gland
males has columnar epithelium with basal nuclei and a larger number of , females have cuboidal epithelium with central nuclei
55
NHP diseases things to know about Cercopithecine herpesvirus 9
host species= macaques AKA simian varicellavirus alphaherpes virus, varicellovirus
56
Lagothrix are animal models for:
cardiovascular research Hepatitis Toxoplasmosis
57
which mouse strains have a high natural prevalance of mammary tumors?
C3H A DBA/2
58
mouse diseases pathology of Polyomavirus in mice
induces tumors in mice affected as neonates typically 2-12 months post experimental infection natural infections are asymptomatic
59
Animal model Hep B and C
Chimps
60
TALEN stands for
transcription activator like effector nucleases
61
strain specific lesions for A/J
congenital defects such as cleft palate, open eyelids, polydactyly progressive muscular dystrophy due to dysferlin mutation systemic amyloidoisis lung tumors
62
NHP diseases things to know about Macacine herpesvirus 3
Beta herpesvirus, cytomegalovirus AKA Rhesus cytomegalovirus disease only occurs in immunocompromised or with intrauterine infection "Owl eye" intranuclear inclusions
63
what species has a hemochorial placenta and how may layers does it have?
human, rodents 3
64
mouse models induction agent for IBD in micee
dextran sodium sulfate (DSS)
65
rat diseases fow many strains of rat parvoviruses are there and describe the common clinical syndromes
4 of them, Kilham's: Toolan's H-1: rat parvovirus: rat minute virus pups of persistently infected dams are protected by maternal antibody, infection of non-immune pregnant femals results in persistent infection of pupb post weanling rats that are exposed develop subclinical infections
66
rat model Obese SHR
Type 4 hyperlipoproteinemia autosomal recessive
67
rat diseases list clinical signs of rat theilovirus
immunocompetent rats= no clinical signs in immunodeficient rats= persistet shedding
68
NHP diseases things to know about Hepatitis E virus
Hepeviridae cynos
69
rabbit diseases buphthalmia
autosomal recessive trait with incomplete penetrance individuals over 3-4 months of age
70
animal model multiple sclerosis/ experimental allergic encephalomyelitis
Callithrix jacchus intradermal injection of homologous myelin basic protein
71
rabbit diseases things to know about myxoma virus
endemic in sylviagus and fatal in oryctolagus flat myxomas lesions in skin fleas and mosquitoes transmit
72
mouse diseases what is the most common pin worms in mice
Syphacia obvelata
73
characteristics of 129 mice
testicular teratomas
74
NHP diseases what is the only pathogenic ameba in NHP
Entamoeba histolytica cause flask shaped ulcers
75
NHP diseases things to know about Campylobacter
C. jejuni and coli high prevanlence but often subclinical infections are self limiting and reinfection is frequent OW and NW
76
pig diseases Things to know about porcine rotavirus
effects 7-28 day old piglets low mortality
77
pig diseases things to know about swine dysentery
Brachyspira hyodysenteriae malabsorptive mucohemorrhagic diarrhea seldom apparent in piglets less than 3wks old
78
rabbit diseases mandibular prognathism
autosomal recessive trait with incomplete penetrance maxilla is short relative to mandible
79
rabbit diseases ulcerative pododermatitis
Staph aureus caging
80
what hormone is responsible for gametogenesis in mice
FSH
81
NHP disease things to know about Mycobacterium avium-intracellulare
saprophytic nontuberculoid mycobacteria causes disease in SIV infected macaques
82
rabbit model induction agent for allergic asthma
ovalbumin in complete freunds adjuvant
83
NHP diseases things to know about Pasteurella multocida
pneumonia, otitis medi recent shipping, poor condition animals
84
Myobia musculi
85
rat model (Lewis) LEW rat is a model for
multiple sclerosis various experimentally induced autoimmune disease
86
mouse diseases name 5 important facts about the parvo viruses that infect mice
immunosuppressive properties natural infections are asymptomatic NS vs VP for differentiation MPV more persistent than MVM experimental infection of MVM in neonates results in renal and intestinal hemorrahge and death; experiemntal infection with MPV does not result in any clinical signs, just persistent lymphocytic infection
87
rabbit diseases things to know about Colibacillosis
E. coli strain O15:H and O103:H2 are most virulent strains in european rabbits 4-5 wks of age, high mortality, other strains cause less severe disease 1-2 week old suckling rabbit high mortality vilous atrophy and fusion in the ileum, cecum and colon antibiotics not recommended- hemolytic uremic syndrome can develop
88
Canine diseases what are the components of the canine infectious respiratory disease complex
Bordatella Strep equi spp zooepidemicus Mycoplasma canine adenovirus type 2
89
which animals have two cervices
rat, rabbit, chinchilla, hamster, opossum, woodchuck
90
mouse diseases clinical signs of infection with mamallian orthoreoviruses
severe pantropic infection in infant mice
91
what is unique about the rodent kidney vs most mammals?
it is unipapillate making catheterization easier vs most mammals which are multipapillate
92
pig models what breed of pig is a model vor vonWillebrand's disease
Poland China
93
NHP diseases things to know about Saimiriine herpesvirus 1
natural host= squirrel monkeys aberent hosts= other new worlds alphaherpes virus, simplexvirus
94
strain specific lesions for DBA
cardiac calcinosis glaucoma
95
rat diseases cestodes found in rats
Rodentolepis nana Hypenolepis diminuta Taenia taeniaformis
96
NHP diseases things to know about Orthomyxoviridae
NHPs can serve as experimental model highly contagious, OW develop upper respiratory clinical signs
97
rabbit diseases rabbit pox virus
rare fatal develop blepharitis, conjunctivitis, and keratitis with corneal ulcers, occasionaly rash or skin lesions present
98
mouse diseases name the two reoviruses that infect mice
Mammaliam orthoreoviruses Group A rotaviruses
99
most common dermatophyte found in mice
Trychphyton mentagrophytes
100
NHP diseases describe the life cycle of Plasmodium
in host has hepatic phase and erythrocytic phase (known as sporozoites and merozoites leading to production of macro and micro gametocytes) Gametocytes are taken up by mosquitoes and the sexual phas begins, form oocyst and then sporozoites which are then spread to host by mosquito
101
rat diseases What neoplasm if the second most common tumor type of F344 rats?
Pituitary adenoma Testicular teratoma is 1st
102
characteristics of C3H/He mice
agouti blind due to rd1 mutation corneal opacities myocardial and skeletal mineralization age related alopecia exogenous murine mammary tumor virus
103
strain specific lesions of 129 mice
acidophilic macrophage pneumonia hyalinosis in other epithelia megaesophageous polyarteritis testicular teratomas
104
animal model Hemochromatosis
Callithrix jacchus
105
rabbit biology three genus in family leporidae
oryctolagus lepus sylvilagus
106
Animal models toxoplasmosis
Lagothrix- woolly monkey
107
rabbit biology what is unique about the rabbit cardiovascular system
tricuspid valve has 2 cusps SA node is easy to identify aortic nerve responds to baroreceptors only, not chemoreceptors
108
rabbit models of infectious disease
Syphilus papillomatosis colibacillosis (RITARD) Campylobacter (RILT)
109
rabbit biology name the two unsual anatomic features of the intestine of the rabbit
sacculus rotundus (cecil tonsil ( ileum empties into) fusus coli- distal portion of colon, smaller diameter regulates hard/soft pellet excretion
110
NHP diseases things to know about human herpes virus 1,2
natural hosts= humans aberent hosts= NW particullarly marmosets alphaherpes virus, simplexvirus
111
animal model Gilbert's syndrome
southdown sheep fasted bolivian squirrel monkeys
112
NHP diseases which nasal mite is found in NW
Pneumonyssoides
113
pig models which breed of pig is a model for high membranous ventral septal defect?
yucatan
114
define a purified diet
each nutrient is derived from a specific ingredient for example, protein from casein or soy, carbohydrate from corn starch or sucrose, fat from lard or corn oil
115
rat diseases rat bladder threadworm
Trichosomoides crassicauda
116
rat diseases What neoplasm is the most common spontaneous tumor of aged Sprague Dawley and Wistar Han rats?
Pituitary adenoma Mammary tumors are 2nd
117
pig diseases Things to know about inclusion body rhinitis
caused by Porcine cytomegalovirus nursing/newly weaned piglets growing pigs are exposed to the virus in the environment and produce their own antibodies, causes abortion when pregnant adult animals are exposed for the first time
118
mouse diseases 4 important things about Spironucleus muris
1- infects crypts of Lieberkuhn, duodenum 2- pathogenic for young, stressed or immunocompromised mice 3- age 3-6 weeks most susceptable 4- moves in zig zag motion
119
pig diseases Things to know about sarcoptic mange
Scaroptes scabiei var. suis acute pruritis
120
Radfordia ensifera (rats)
121
NHP humans are most likely to be infected with which species of Plasmodium
vivax, falciparum,
122
mouse diseases what are the primary differences between MAdV-1 and 2
1 causes fatal multisystemic infection in suckling mice, 2 is typiclaly asymptomatic but is enterotropic in mice less than 3 wks of age 1 causes necrosis of liver, spleen, intranuclear inclusions; 2 causes intranuclear inclusion in mucosal epithelial cells of small intestine
123
mouse diseases 4 important things about Pseudomonas aeurogenosa
1- clinicall silent in immunologically competent animals, opportunist 2- chronically inhabits nasopharynx, GI tract, 3- dx by clinical signs and history of immunosuppression 4- found in water, acidification to 2.5pH or hyperchloriation to 10 ppm of drinking water
124
Animal model visceral Leishmania
Chlorocebus aethiops
125
Animal models model for HIV
baboons and pig tailed macaques will develop disease and immunosuppression with HIV 2 infection
126
which mice species are prone to retinal degeneration?
c3H and CBA
127
what is the most common hematopoietic malignancy
lymphoma lymphocytic leukemia originating from the thymus
128
animal model motion sickness
Saimiri
129
rat diseases 3 important things to know about Pseudomonas aeruginosa
widely distributed in water, soil, sewage wide host range rarely see unless immunosuppressed
130
NHP diseases things to know about Poliovirus
Picornaviridae Macaques serve as experimental model typically no CS if no immune responce can see poliomyelitis and skeletal muscle atrophy
131
dog models which breed is a model for Diabetes mellitus
Keeshond
132
mouse diseases list the common coccidians found in mice
Eimeria falciformis Klosiella muris Cryptosporidium muris, parvum Entamoeba muris Encephalitozoon cuniculi Toxoplasma gondii
133
dog models gray collie syndrome
cyclie hematopoiesis
134
use of FVB mice in genetic engineering
microinjection into large pronucleus
135
characteristics of C57BL/6 mice
hydrocephalus hippocampal neurodegeneration micropthalmia and anophthalmia age related cochlear degeneration malocclusion pulmonary proteniosis epithelial hylanosis late onset amyloidosis TH1 skewed immune response
136
rabbit diseases things to know about rotavirus infection
yes, rabbits have one too mild diarrhea, mucoid weaning age most susceptible
137
Animal models Leprosy
Cercocebus torguatus atys- sooty mangaby Dasypus novempictus- armidillo
138
characteristics of mouse urine
creatinine is excreted instead of creatine taurine present, tryptophan is absent
139
NHP diseases things to know about monkey adenovirus
Adeniviridae respiratory and enteric disease but subclinical infection common used in research as gene delivery method in immunocompromised animals=necrotizing pancreatitis
140
pig diseases Things to know about Leptospirosis
caused by Leptospira interrogans- serovars pomona and bratislava
141
pig management recomendations for vaccination
erysipelas and leptospirosis breeding add Porcine parvovirus, bordatella, pasturella, e coli
142
rat models Brown Norway (BN) rat is a model for
inducible, transplantable myeloid leukemia hydronephrosis bladder carcinoma
143
rabbit diseases dermatophytosis
trichophyton mentagrophytes no pruritis zoonotic asymptomatic carriers
144
Syphacia obvelata (mice)
145
NHP diseases things to know about Moraxella catarrhalis
epistaxis and mucohemorrhagic discharge
146
rat diseases most common pinworm
Syphacia muris
147
rat diseases What are the three gastrointestinal bacterial pathogens of rats?
Clostridium piliforme Salmonella entereditis Helicobacter
148
rat diseases list the two corona viruses of rats
Parkers rat corona virus Sialodacryoadenitis virus
149
pig diseases list the causative agents of atrophic rhinitis
Bordetella bronchiseptica and Pasturella multocida
150
Pig diseases important things to know about Mycoplasmal polyserositis
caused by Mycoplasma hyorhinis 3-10wks aerosol spred, assoicated with stress
151
NHP diseases things to know about yellow fever
flaviviridae asymptomatic in OW, NW are susceptible mosquitoes zoonotic Councilman bodies (eosinophilic inclusions) Torres bodies (eosinophilic intranuclear inclusions)
152
Animal models natural hosts for SIV
african green, sooty mangabeys, and mandrills cause disease (AIDS like) in macaques
153
mouse diseases 3 important things to know about K virus
1) tropism for vascular endothelium 2) persistent infection in adults and infants in the renal tubular epithelium 3) intranuclear inclusions in vascular endothelium of small intestine and brain, lung liver
154
canine diseases zoonotic disease associated with Ancylostoma caninum
cutaneous larval migrans
155
what is the most common ectoparasite in mice
Mycoptes musculinis
156
rat diseases 4 important things to know about Clostridium piliforme
Tyzzers disease affects numerous species usually clinically silent, unless recently weaned or immunosuppressed liver heart GI lesions
157
rat model COP (Copenhagen) rat is a model for
prostate adenocarcinoma
158
rabbit diseases proliferative enteropathy
lawsonia intracellularis weanlings most commonly affected
159
pig diseases Things to know about Swine Enzootic Pneumonia
caused by Mycoplasma hyopneumoniae 3-6 mo old infected (most common in grower and finisher pigs) central role in porcine respiratory disease complex
160
NHP diseases things to know about Tanapox
yabapoxvirinea host=african green monkey, infects macaques both intracytoplasmic and intranuclear inclusion bodies in the epidermis
161
pig diseases Things to know about porcine reproductive and respiratory syndrome
arterivirus clinical signs as name suggests
162
NHP diseases things to know about Klebsiella pneumoniae
normal flora of upper and lower GI tract can infect upper respiratory tract and cause disease pneumonia, air saculitis, septicemia, peritonitis OW and NW
163
Animal model Bancroftian filariasis
Presbytis cristatus (silvered leaf monkey)
164
what species do not have a gallbladder
rat, horse, camel, dophin, elephant, pigeon, some hamsters (Chinese and European do not, Siberian and Russian do)
165
mouse diseases 4 important things about Aspicularis
1- 23-25 day life cycle 2- diagnose by fecal float 3- eggs are ellipsoidal 4- require 6-7 days incubation to become infective
166
Pig diseases List 4 diseases that cause arthritis in pigs
Haemophilus parasuis (Glassers disease) Streptococcus suis Erysipelas rusiopathiae Mycoplasma polyserositis
167
Animal model Hep A and E
Owl, chimps, marmosets
168
describe the Lee Boot effect
estrus supression in group housed females
169
NHP diseases things to know about Salmonellosis
S. typhimurium, choleraseuis, anatum, stanley, derby, and oranienburg starts out as GI but can progress to septicemia in neonates, abortion,and pyelonephritis carrier state can develop, especially if treated with antibiotics
170
mouse diseases name the two parvo viruses of mice
minute viruse of mice mouse parvovirus
171
what CNS ventricular structure does the rat lack
foramen of Magendie
172
mouse diseases 4 important things about Staphylococcus
1. aureus is highly pathogenic while epidermidis is nonpathogenic 2. in nude mice, aureus = furunculosis, gland absecesses 3. C57/BL6, C3H, DBA, BALB/c are susceptible 4. suppurative ulcerative and necrotic dermatitis in young mice
173
rabbit diseases things to know about rabbit hemorrhagic disease
calicivirus 3 clinical syndromes: peracute/sudden death acute/ anorexia, depression, ocular hemorrhage and epistaxis subacute/ milder and most survive periportal hepatic necrosis is only consistent microscopic lesion
174
what are the primary uses of 129 mice in genetic engineering
source of embryonic stem cells
175
NHP diseases clincial disease seen with Tritrichomonas mobilensis
diarrhea in squirrel monkeys
176
Animal model Gonorrhea
Pan troglodytes
177
Mouse diseases 4 important things about CAR bacillus
1- more significant in rats 2- natural clinical disease is rare 3-silver stain (Warthin-Starry) for diagnosis 4- co pathogen with SV and PVM
178
pig diseases Things to know about Porcine parvovirus
when sows are exposed at \<70 days gestation natural exposure of gilts entering breeding herd leads to development of transferable immunity
179
animal model labor and pelvic organ prolapse
Saimiri
180
rabbit diseases things to know about Psoroptes cuniculi
inner surfaces of external ear otoacariasis (ear canker)
181
Animal models Malaria
Owl and Squirrel monkeys
182
rabbit models infection with what agent leads to development of hypercalcemic nephropathy?
VX2
183
rabbit diseases things to know about the rabbit pinworm
Passalurus ambiguus perpatent period 56-64 days, eggs are immediately infective
184
animal models lymphocytic Thyroiditis
Callithrix jacchus
185
rat diseases 4 important things to know about Corynebacterium kutscheri
pseudotuberculosis multiple randomly distributed abscesses in lungs, liver (rat=lungs) latent infections in submaxillary lymphnode disease more frequent in older animals
186
rat diseases clinical disease with reovirus?
No, only seroconvert
187
NHP models Cercocebus atys
sooty mangaey AIDS/SIV leprosy
188
Animal models Varicella
Erythrocebus patas Chlorocebus aethiops
189
NHP diseases things to know about Simian T-lymphotropic virus
retrovirus, deltaretrovirus, type C retrovirus OW, not NW (Baboons, AG, and macaques) usually subclinical, latency, develop tumors
190
mouse diseases 5 important things about Mycoptes musculinis
1- found in the inguinal region, abdomen, back but also on head and neck 2- causes pruritis 3- 8-14 day life cycle 4- feed on superficial epidermis 5- heavily chitinized, "boxing gloves" on last two legs
191
NHP models Chlorocebus
grivet, vervet infectious diesease- yellow fever, plague, **_leprosy_**, hepatitis **_legionnaires disease_**, varicella
192
rat biology which hormonal reproductive effects are seen in rats
Lee Boot effect (minimally). no Bruce or Whitten
193
NHP diseases things to know about Molineus elegans
small intestine of NW (particullarly capuchin and squirrel) nematode
194
animal models stress
Saimiri (naturally high cortisol levels)
195
Callithrix are animal models for:
Parkinson's disease Multiple sclerosis Hemochromatosis
196
rat model F-344 is a model for
toxicology inbred by NAtional Toxicology Program
197
rat diseases which strains are most susceptible to chronic progressive nephropathy?
F344 Sprague Dawley
198
how many toes does the mouse have on each foot
5 on front and 5 on back
199
mouse diseases important things to know about LDHV (lactate dehydrogenase elevating virus)
Arteriviridae asymptomatic, disease requires immunosuppression **_transmitted via infected biologicals_** LDH can be 5-20x normal C58, AKR develop paralytic syndrome which is age dependent passage through rats eliminates from biologicals
200
NHP diseases things to know about Macacine herpesvirus 5
ADA rhesus rhadinovirus gammaherpesvirus, rhadinovirus lymphadenopathy SIV immune mediated anemia
201
rabbit diseases things to know about papillomavirus infections
cottontail (shope) papillomavirus horny warts, cottontail rabbits are natural host arthropod spread oncogenic (squamous cell carcinomas) used to study oncogenic virus biology
202
NHP diseases name the 2 trematodes found in NHP
Gastrodiscoides hominis Schistosoma spp
203
NHP diseases things to know about Mycobacterium Leprae
chronic granulomatous disease affecting the skin and peripheral nerves with lesions preferentially occuring in cooler areas sooty mangaby (Cercocebus atys) and chimpanzees
204
rabbit diseases intestinal coccidiosis
Eimeria post weanling rabbits most likely to experience mortality suckling rabbits are considered resistant vaccine sprayed into nest box when rabbits are 25 days of age
205
rabbit diseases things to know about hydrocephalus
single autosomal recessive hypovitaminosis A
206
NHP diseases which species of Plasmodium are NW NHP most likely to be infected with?
simium, brazilianum
207
pig biology what is unique about the pig lymphnode?
it is inverted, with germinal centers located in the internal portion of the node similar to elephant, rhino, dolphin, hippo, and warthog
208
Animal model toxemia of pregnancy
Erythrocebus patas
209
animal models Strabismus
saimiri
210
NHP diseases things to know about Encephalomyocarditis virus
Picornaviridae rodents are carriers baboons usually found dead
211
NHP diseases most susceptible NHP to Giardia
macaque with SIV
212
describe the changes that occur in the adrenal glands in mice
X-zone between medulla and cortex in immature males and young virgin females
213
Canine diseases which serovars of Leptospirosis are dogs most commonly infected with?
Grippotyphosa, pomona, Bratislava
214
215
Canine diseases things to know about Canine herpes virus
turkey egg kidneys rapidly fatal disease in puppies
216
rat diseases 3 things about hantavirus
bunyviridae rodents are natural reservoir infections are chronic and subclinical
217
which species have an epitheliochorial placenta and how many layers does it have
cow, pig, horse 6 layers
218
rabbit diseases list the three pox viruses found in rabbits
myxoma virus rabbit (shope) fibroma virus rabbit pox virus
219
Aspicularis tetraptera
220
Which mouse strains are most susceptible to amyloidosis?
A and SJL
221
orbital sinus vs plexus
mice have sinus rats have plexus
222
Canine diseases list the most common roundworm of dogs
Toxascaris canis Toxascaris leonina
223
pig diseases Which organisms are responsible for coccidiosis in pigs?
Eimeria Cryptosporidium parvum Isospora suis 5-10 days Or suckling and recently weaned pigs mild disease
224
rabbit diseases which gamma herpes viruses have been isolated from cottontail rabbits
1 and 3
225
rat diseases What is the most important disease of aging rats
chronic progressive nephropathy
226
rabbit diseases splay leg
simple autosomal recessive inheritance unable to adduct typically hindlimbs
227
NHP diseases things to know about Lawsonia intracellularis
proliferative enteritis
228
NHP diseases list the 2 cestodes (tapeworms) found in NHP
Spargana Echinococcus
229
which mouse strain has a high incidence of thymic lymphoma from murine leukemia retrovirus
AKR
230
Animal model Parkinson's Disease
Callithrix jacchus MPTP
231
rat diseases 4 things to know about Clostridium piliforme
1. Tyzzer's disease 2. rats less commonly affected that mice 3. peracetic acid is prefered disinfectant 4. intestine, liver heart in rats (mice no heart)
232
NHP diseases which nasal mite is found in OW NHP
Pneumonyssus
233
pig diseases things to know about pig lice
Haematopinus suis sucking lice pruritis
234
what does / stand for in mouse nomenclature
substrain
235
mouse diseases 4 important things about Myobia musculi
1- 23 day life cycle 2- cause of hypersensitivity 3- one empoidial claw 4- found on head, neck, and shoulder regions
236
NHP diseases things to know about Nocardia spp
saprophytes multinodular areas of consolidation of pulmonary lesions look like coccidiomycoides or TB
237
rabbit diseases Clostridium difficile
affect ileum and jejunum instead of cecum I
238
NHP diseases things to know about Kyasanur Forest Disease
flavivirus Bonnet macaques are model ixodid ticks spred
239
rat model Brattleboro rat is a model for
diabetes insipidus (autosomal recessive)
240
NHP diseases things to know about Histoplasma capsulatum
think baboons and skin touching the ground
241
rat diseases three things to know about Salmonella enterica
clinical signs are rare and unspecific hepatitis with white spots culture on selenite broth, brilliant green or MacConkey agar
242
define a chemically defined diet
formulated with very basically defined ingredients, ie specific animo acids, sugars, triglycerides, and essential fatty acids
243
rat models BB/Wor is a model for
juvenille insulin dependent diabetes mellitus
244
NHP diseases things to know about yatapox
yabapoxviridea macaques and baboons zoonotic SQ masses
245
mouse diseases list the two herpes viruses that infect mice
mouse cytomegalovirus (Beta herpes) mouse thymic necrosis virus
246
rabbit biology describe the rabbit estrous cycle
they do not have one, induced ovulator
247
rabbit diseases things to know about Enterotoxemia
caused by Clostridium spiroforme (primary pathogen) young rabbits/change in gut flora
248
pig models name the two primary uses for swine
surgical models xenotransplantation
249
NHP diseases things to know about simian parvirus
parvoviridae erythrocytic tropism potential zoonosis fulminant hepatitis and rheumatoid arthritis
250
Radfordia affinis (mice)
251
characteristics of FVB mice
blind due to homozygosity at rd1 allele prone to seizures prone to persistent mammary hyperplasia
252
rat diseases 5 things to remember about CAR bacillus
1. overt disease is uncommon 2. wide host range 3. clinical signs and gross lesions are indistinguishable from Mycoplasma 4. silver stain 5. forms large bronchial abscesses
253
Pig diseases Things to know about Erysipelas rhusiopathiae
diamond skin disease 3mo-3ys of age (growing or adult) acute=septicemia and death chronic= enlarged stiff joints, diamond shaped lesions carriers are source, shed in feces zoonotic
254
255
describe the Witten effect
estrous induced by introduction of male pheremones
256
NHP diseases things to know about Shigella
S. flexneri, boydii, sonnei both OW and NW think diarrhea and gingivitis (also abortion and air sac infection) large intestine culture on three successive days
257
rabbit models induction agent for model of inflammatory bown disease
dinitrochlorobenzene (DNCB)
258
consomic
chromosome substitution
259
rabbit diseases things to know about malignant lymphoma
tetrad of lesions, kidneys-splemonegaly- lymphadenopathy
260
rat biology estrous cycle of the rat
4-5 days continuously polyestrous
261
NHP diseases things to know about rotaviruses
reoviridae self limiting watery diarrhea
262
rat diseases What is the suspected cause of auricular chonritis?
immune mediated reaction to Type II collagen
263
animal model Spongiform Encephalopathy
Saimiri
264
rat diseases 3 things to know about Corynebacterium kutscheri
1. in rats most commonly affects lungs (multisystemic in mice) 2. can cause persistent asymptomatic infections 3. methenamine silver stain
265
rat diseases What are the 6 bacterial respiratory pathogens?
Streptococcus pneumoniae Corynebacterium kutcheri CAR Mycoplasma pulmonis Pasturella pneumotropica Streptobacillus moniliformis
266
uses of C57BL/6 in genetic engineering
most often used background strain
267
rabbit biology name the salivary gland that does not have a human counterpart
zygomatic
268
strain specific lesions of BALB/c
epicardial mineralization and cardiomyopathy imperforate vagina and mucometra B cell lymphoma/reticulum cell sarcoma mammary adenocarcinoma
269
Rat biology What is the name of the gland found in the rostral nasal cavity of the rat that contributes to maintenance of mucous blanket covering the ciliated respiratory surfaces
Steno's gland seems to be unique to the rat
270
NHP models Erythrocebus patas
Patas monkeys pregnancy toxemia
271
rat diseases which rat strain is most susceptible to myocardial degeneration/fibrosis
aged Sprague Dawley
272
mouse diseases 4 important things about Clostridium piliforme
1. Tyzzers disease 2. C57CL/6 resistant, DBA, CBA susceptible 3. environmental decontamination difficult 4 trifecta of clinical signs (GI, heart, liver) heart rare in mice 5. pickup sticks on silver stain
273
rabbit diseases scarptes scabiei
pruritic burrowing mite
274
rat diseases Which rat strain is most prone to testicular neoplasms
F344
275
NHP disesases things to know about macacine herpes virus 1
AKA B virus alpha herpes virus, simplexvirus natural host=macaque aberent host= humans
276
rat diseases 2 things to know about Sendai virus in rats
1. paramyxovirus 2. asymptomatic and self limiting in rats, unlike in mice
277
what species have an endotheliochorial placenta and how many layers does it have
dog, cat 4
278
rat model ACI rat is a model for
congenital genitourinary anomalies prostatic adenocarcinoma
279
rat diseases Which rat strain is most susceptible to polyarteritis nodosa
SHR
280
rat biology significance of left azygous vein in pigs
drains intercostal vessels into coronary sinus different from other mammals where it enters the precava
281
mouse diseases 6 important things to know about LCMV
Arenaviridae 4 biotypes (1. late disease 2. cerebral 3. mortality/neonatal runting 4. viscerotropic) non-cytolytic/ minimally pathogenic but experimental intracerebral injection can cause disease ZOONOTIC think hamsters for amplification prototype for T lymphocyte mediated immune injury
282
NHP diseases things to know about Hepatitis B virus
Hepadnaviridae Chimps
283
NHP diseases things to know about monkeypox
orthopox papules leading to vesicular rash, pock lesions (including hands and feet) intracytoplasmic inclusion bodies
284
rabbit diseases things to know about Pastureloosis
head tilt snuffles weanlings suppurative inflammation use SPF rabbits
285
NHP diseases things to know about Rhesus papillomavirus
Papillomaviridae hyperplasiaof stratum spinosum and corneum with spontaneous resolution
286
mouse diseases what are 3 important things about mouse herpes viruses
1) natural infections are asymptomatic, no matter the strain 2) persist in the salivary glands 3) pathology of cytomegalovirus is megalocytes with eosinophilic intranuclear inclusions in cervical salivary glands. pathology of mouse thymic cirus is thymic necrosis with intranuclear herpetic inclusions
287
pig diseases Things to know about Pleuropneumonia
Actinobacillus pleuropneumoniae less than 6mo, peak mortality 10-16 weeks severe pleuropneumoniae, sudden onset, high mortality and high morbidity can become chronic or carrier forms
288
rat diseases list 3 things you should know about Streptococcus pneumoniae
1. usually asymptomatic 2. fibrinopericarditis, fibrinopleuritis are classic lesions 3. Optochin test (zone of growth inhibition on blood agar plates) and Neufeld-Quellung reaction- swelling of capsule
289
characteristics of BALB/c
males pugilistic dystrophic epicaridal mineralization auricular thrombosis corneal opacities resistant to spontaneous amyloidoisis TH2 skewed immune response
290
rabbit diseases list the three gamma herpes viruses of rabbits
leporid herpesvirus 1,2,3
291
rat biology describe the biology of the salivary glands in rats
parotid- serous submaxillary/submandibular= mixed sublingual= mucous
292
mouse diseases 4 important things about Sendai virus
paramyxovirus no persistent state in immunocompetent mice C57 highly resistant; DBA/2 are susceptable bronchial and interstitial pneumonia
293
Saguinus are animal models for:
Viral hepatitis colonic adenocarcinoma IBD
294
pig diseases THings to know about Transmissible Gastroenteritis
Coronavirus all ages, \<2wks severe signs diarrhea and vomiting
295
Polypax serrata is found in what species of rodents and is the vector for what blood borne parasite
mouse, Mycoplasma coccoides
296
CrISPR stands for
clustered interspaced short palindromic repeats
297
rabbit diseases which gamma herpes viruses cause disease
leporid herpesvirus 3, lymphoproliferative disease with lymphoid infiltration of many organs
298
mouse diseases what organisms are known for causing white spots on the mouse liver
Corynebacterium Yersiniosis Salmonellosis Tyzzers Ecromelia Reovirus MHV Pasturella Helicobacter
299
NHP diseases NHP most likely to be infected with Cryptosporidium spp
immunosuppressed macaques
300
canine diseases what is the hookworm found in dogs?
Ancylostoma caninum Ancylostoma braziliense
301
mouse diseases 4 things about Encephalitozoon cuniculi
1- think rabbits and brain/neuro and kidney 2- no clinical signs in mice 3- microsporidian 4- stain with either Giemsa or Goodpasture
302
NHP diseases things to know about Macacine herpesvirus 4
AKA Rhesus lymphocryptovirus gammaherpesvirus, lymphocryptovirus natural host= ? aberent host= Rhesus coinfection with SIV leads to lymphoma or lesions resembling oral hairy leukoplakia
303
mouse diseases identify the two papovaviruses that infect mice
Polyomavirus and K virus (Kilham virus)
304
what does (c) stand for in mouse nomenclature
recombinant congenic
305
list mouse caging material from most durrable to least
polyethylene, polystyrene, polypropylene, polycarbonate, polyethermide
306
pig diseases Things to know about Porcine circovirus associated disease
Type 2 Post weaning multisystemic wasting syndrome, porcine dermatitis and nephropathy syndrome, porcine respiratory disease complex and occasionally repro failures
307
NHP diseases things to know about Bordatella bronchiseptica
commensal in nasopharynx respiratory disease
308
in what species is proteinuria normal
rats and dogs
309
Pig diseases Things to know about Pasteurellosis
severe suppurative bronchopneumonia primary= septicemia in piglets secondary= in conjunction with other diseases and stress
310
mouse diseases 3 important things about Pasturella pneumotropica
1- subclinical opportunistic pathogen, if immunosuppressed will see clinial signs 2- suppurative inflammation and abscesses 3- ubiquitous inhabitant of skin, upper respiratory tract and GI
311
rat diseases what is the most common mite? description?
Radfordia ensifera two claws EQUAL length
312
what does (;) stand for in mouse nomenclature
incipient congenic
313
mouse diseases 8 important things about Salmonella
1. serovars Typimurium and Enteritids 2. Zoonotic 3. nutritional iron deficiency has attenuating effect 4. BL6, C3H are susceptible, AJ, CBA are intermediate, 129 are resistant 5. 3 types of infection seen acute in young mice; subactue mice have distended abdomens with hepatomegally and splenomegally, chronic mice have weight loss and anorexia 6. granulomatous lesions leading to septic thrombi 7. enrich with Selenite F cystine broth before culture 8. subclinical carriers and chronic carriers are seen when animals recover
314
NHP diseases CS seen with Sarcocystist kortei or nesbitti
monkey is intermediate host (get from eating raw monkey) think white nodules in mesentery and serosa, no inflammatory reaction
315
NHP diseases things to know about Yersina
Y. enterocolitica and pseudotuberculosis fulminating enteric and septicemic disease NW and OW Squirrel monkeys=cervical lymph nodes enlarged will also see vomiting and severe abdominal pain
316
pig biology hormone to detect pregnancy
esterone sulfate, peak at 23-30 days gestation, produced by fetus
317
rabbit diseases things to know about alpha herpesvirus infection
leproid herpesvirus 4 from domestic rabbits severe disease in preweanlings
318
pig biology which breeds are susceptible to malignant hyperthermia
Duroc, Yorkshire, Poland China, Landrace, Pietran damn you poor little piggy
319
NHP diseases things to know about the measles virus
Paramyxoviridae, morbillivirus Rhesus monkey is model for measles infection Koplik's spots respiratory and derm signs, NW get GI causes immunosuppression
320
NHP diseases things to know about Saimiriine herpesvirus 2
natural host= squirrel monkey aberent host= other new worlds, owl monkeys lymphoma, lymphocytic leukemia (model for Burketts lymphoma) gammaherpesvirus, lymphocryptovirus related to Epstein-Barr virus/infectious mononucleosis
321
rabbit diseases hepatic coccidiosis
Eimeria stiedae younger, more cysts multifocal yellowish white lesions of varying size and white streaks on liver bile and gallbladder also
322
NHP diseases things to know about Rabies virus
rhabdoviridae, lyssavirus vaccinate, attenuated vaccines are bad-can produce disease in NW
323
rat diseases 3 things to know about M. pulmonis
1. natural host for M. pulmonis 2. persistent life long infection 3. single most important historical infectious complication of research
324
rabbit diseases most common tumor in rabbits
uterine adenocarcinoma
325
mouse diseases 5 important things about Mousepox virus
1) 3 forms of disease asymptomatic, chronic, acute lethal 2) liver, spleen and epithelial cell lesions with inclusions are pathognomonic 3) Marchal bodies (type A intracytoplasmic inclusions) acidiphilic well demarcated incusion bodies in epuithelial cells. Type B are basophilic and found in internal organs 4) DBA/1, DBA/2, BALB/c, A, C3H are most susceptible C57BL6, AKR are most resistant 5) orthopox virus
326
NHP diseases things to know about Simian virus 40
polyomavirus common latent infection but clinical disease associated with immunosuppression brain, lung, kidney lesions,
327
what hormone is responsible for secreation of androgens
LH
328
rat diseases 3 things about rat cytomegalovirus
Beta herpesvirus low significance as no known natural infections latency in salivary glands
329
pig models which breed is a model for melanoma
Sinclair
330
conplastic
mitochondiral substitution
331
mouse diseases 5 important things to know about mouse hepatitis virus
1) corona virus 2) 2 strains- enterotropic and neurotropic/respiratory/ multisystemic infects suckling mice less than 2 wks of age 3) necrosis and **_syncytia_** of either intestinal villi or nasal mucosa or multiple organs 4) persistent infection of immunocompromised mice 5) SJL and A/J mice are resistant; BALB/c and DBA/2 are susceptible
332
NHP diseases things to know about Nochia nochi
stomach, pouches that look like cauliflower nematode
333
NHP diseases things to know about Simian Hemorrhagic Fever Virus
arteriviridae Patas, AG, and baboons are reservoir Macaques fata bleeding syndrome hemorrage and necrosis of proximal duodenum (not hepatic or adrenal)
334
rat diseases Which strain is most prone to mammary neoplasms?
Sprague Dawley F344 and Wistar Han are second
335
Animal models Colonic adenocarcinoma, ulcerative colitis/IBD
Sagunius oedipus
336
NHP diseases things to know about Simian Immunodeficiency virus
retrovirus, lentivirus low pathogenicity in African, disease in Asian zoonotic persistent lymphadenopathy, tropism for CD4 T cells
337
rule of thumb for salivary gland products
parotid= serous submaxillary= mixed (serous in mice) sublingual= mucous
338
pig diseases List the common respiratory diseases of swine
mycoplasmal pneumonia atrophic rhinitis pasteurellosis inclusion body rhinitis pleuropneumonia Swine flu pseudorabies (Aujeszky's disease)
339
NHP diseases things to know about the Filoviruses
Ebola and Marburg Marburg= from AG monkeys adrenal and hepatic necrosis
340
rabbit models mutation seen in Watanabe Heritable Hyperlipidemic Rabbit
LDL receptor deficent
341
Pig diseases Important things to know about Streptococcus suis
5-16 wk old most susceptible (nursing or recently weaned pigs) Meningitis, arthritis zoonotic fibrinous bronchitis, pleuritis, pericarditis
342
rabbit biology unique characteristics of reproductive tract
duplex uterus with separate cervices inguinal pouches located lateral to genetilia in both sexes inguinal canals are open in males
343
NHP diseases things to know about Colibacillosis
frequent normal fecal isolate but may or may not cause clinical disease EPEC is common pathogen of SIV infected macaques NW and OW
344
what does (x) stand for in mouse nomenclature
recombinant inbred
345
animal model Legionnaires Disease
Cavia procellus Callithrix jacchus Chlorocebus aethiops Macaca mulatta
346
canine diseases zoonotic disease associated with Toxascaris canis
visceral larval migrans and ocular larval migrans
347
rabbit models induction agent for acute acalculous cholecystits
lysophosphatidylcholine
348
pig biology describe the important facets of pig coronary anatomy
right sided dominant and no pre-existing collateral circulation
349
NHP biology tamarins are more susceptible to which diseases and why?
viral limited MHC class I
350
mouse diseases 4 important things about Corynebacterium
1. pseudotuberculosis- liquifactive caseous material 2. bovis- orthokeratotic hyperkeratosis, scaly skin 3. "chinese letters" 4. differential for low humidity.
351
pig diseases Things to know about greasy pig disease
Staph hyicus 5days-2mo no pruritis
352
mouse diseases identify the two adenoviruses of mice
MAdV-1 and 2 or A and B
353
mouse diseases What is the principal intermediate host for Toxoplasma gondii? The definitive host?
mouse cat
354
Animal models Diabetes mellitus
Macaca nigra
355
mouse diseases 2 important things about Radfordia affinis
1- causes little to no inflammatory reaction 2- two empodial claws of unequal length
356
mouse diseases 4 important things about Theilers murine encephalomyelitis virus
1) mouse polio virus, Cardiovirus 2) experimentally induced neurologic disease, demyelinating phase, paralysis, some recovery 3) replicates in intestinal mucosa 4) SJL, DBA/2, C3H are susceptable; BALB/c, B6, 129 are resistant
357
Animal models chronic destructive periodontitis
Oryzomys palustris- rice rat Callithrix jacchus- common marmoset
358
Saimiri are animal models for:
pharmacology/toxicology neuroscience CJD malaria labor and pelvic organ prolapse
359
Canine diseases which protozoal diseases are associated with immunosuppression
Isospora
360
Which mouse strains are resistant to amyloidosis?
C57BL, BALB/c and C3H
361
strain specific lesions for C3H
dystrophic cardicac calcinosis hamartomas mammary tumors
362
pig diseases importatnt things to know about Pseudorabies
Aujeszky's disease herpes virus latent in sensory ganglia high mortality in pigs under 9 weeks of age reportable disease
363
rat diseases the rat louse has what name and is the vector for what hemoplasma
Polyplax spinulosa Mycoplasma haemomuris
364
NHP diseases things to know about Dengue Hemorrhagic Fever
flavivirus macaques are asymptomatic mosquito transmits zoonotoic
365
pig diseases Things to know about Proliferative Ileitis/enteritis
caused by Lawsonia intracellularis pigs 6-20 wks infected hyperplasia of crypt enterocytes wide host range silver stain
366
NHP diseases things to know about Anatrichosoma spp
think white lines on hands and feet nematode
367
rabbit model heratibility of the WHHL model?
autosomal dominant
368
rat diseases What anesthetic agent is known to cause adynamic illeus
Cloral hydrate
369
NHP diseases most common nematode in OW and great apes
Oseophagostomum
370
NHP models Pan troglodytes
AIDS HEP B,C cognition and language development
371
describe the difference between male and female mouse kidneys
cuboidal epithelium lining Bowman's capsule in males, squamous epithelium in females
372
Aotus are animal models for:
malaria cutaneous and visceral leishmaniasis viral hepatitis A vision
373
rabbit biology what is unique about the alkaline phosphatase of rabbits
they have three isoforms (liver , intestinal and kidney. other mammals have 2 intensinal and liver/kidney/rest)
374
NHP diseases things to know about Pneumocystis
species specific ubiquitous in the environment associated with SIV or other immunodeficiency
375
pig diseases things to know about Salmonellolsis
S. choleraesuis, typhimurium, typhisuis 3wks-5m old respiratory, enteric, and repro systems
376
rat diseases describe the clincial syndromes seen with sialodacryoadenitis virus
corona virus breeding colonies, mature rats are immune, clinical disease is associated with preweanling animals enzootic in epizootic, post weanling to adult rats are exposed and develop cervical swelling due to infallmmation and edema of submaxillary glands in immunodeficient rats, see persistent infection
377
rabbit diseases Treponematosis
Treponema paraluiscunniculi (similar to T. pallidum) rabbit syphylis spirochetes with Warthin starry silver stain tests: RPR rapid plasma reagin card test or veneral disease research laboratory slide test
378
rat biology transfer of antibodies from mom to pup occurs when?
in utero via the yolk sac intestinal absorption of colostrum for up to 16 days postpartum
379
NHP disease name the sucking louse found in NHP
Pediculus
380
rat biology hearing range of rat
500Hz to 60-80kHz
381
rat model Zucker rat is a model for
obesity
382
383
rat model SHR (spontaneous hypertensive rat) is a model for
hypertension cardiovascular research
384
what does : stand for in mouse nomenclature
outbred
385
rabbit diseases things to know about rabbit (shope) fibroma virus
fibramatosis endemic in wild rabbits spread by arthropods fibromas are flat, subcutaneous, eaisly moveable tumors
386
rat diseases 3 things to know about Streptobacillus moniliformis
1. causative agent of rat bite fever 2. commensal of nasopharynx of wild rats 3. does not cause disease in rats
387
Mouse diseases 7 important things about Mycoplasmosis
1- chattering 2- rats are reservoir for mice 3- C57BL6 resistant; BALB/c, C3H, DBA/2 are susceptible 4- treatment only suppresses disease 5- T cell response exacerbate clinical signs 6- cobble stone appearance of lungs 7- nude/SCID mice develop systemic disease
388
rat diseases What rat strains have a high prevalence of hydronephrosis?
Brown Norway Gunn Zucker
389
rabbit diseases things to know about coronavirus
pleural effusion disease congestive heart failure
390
NHP diseases which pentastomes are found in OW
armillifer and porocephalus
391
NHP diseases Simian Retrovirus (SRV)
retrovirus, betaretrovirus, type D zoonotic CS= generalized lymphadenopathy, retroperitoneal fibromatosis when infected with gamma herpesvirus broad immune cell tropism
392
animal models cutaneous leishmania
Aotus Saguinus
393
mouse diseases name the two paramyxoviruses that infect mice
Sendai Murine pneumonia virus
394
animal models Crohn's disease
terminal ileitis in Saguinus mystax and labiatus
395
rabbit models difference between WHHL and St Thomas rabbits
St Thomas have normal LDL receptors
396
pig diseases List the common enteric diseases
swine dysentery proliferative Ileitis Colibacillosis Clostridial enteritis transmissible gastroenteritis rotaviral enteritis
397
rat diseases Which rat strain is most susceptible to Alveolar histiocytosis?
F344 and Sprague Dawley
398
mouse diseases 4 important things to know about Group A rotaviruses (murine rotavirus)
EDIM high morbidity, low mortality affects mice less than 2 wks of age terminally differentiated enterocytes, vacuolation at the tips

ACLAM study sets (22 decks)

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