BB Ch 2

Question 1

AWA of 1966

Answer 1

licensing of dealers of dogs and cats. treatment before and after research

Question 2

AWA of 1970

Answer 2

expanded to include regulated animals to include teaching, exhibition, wholesale pet industry, zoos. standards of care during research and includes more species

Question 3

AWA of 1976

Answer 3

transportation guidelines

Question 4

AWA of 1985

Answer 4

expanded to include IACUC, develop a national agriculture library, training of personnel

Question 5

AWA of 1990

Answer 5

expanded to include holding period regulations

Question 6

Fiscal year under AWA

Answer 6

Oct 1st to Sept 30

Question 7

Annual report for AWA is due?

Answer 7

by Dec 1st

Question 8

What should be in annual report to AWA/USDA

Answer 8

1. assure professionally acceptable standards were followed 2. each investigator considered alternatives

Question 9

when can exceptions to standards of care be issued?

Answer 9

1. for health reasons. veterinarian can approve exemption that must be reviewed every 30 days unless it is a permenant condition

Question 10

What type of information should the NAL provide

Answer 10

1) info pertaining to employee training

Question 11

Who enforces AWA

Answer 11

USDA thru APHIS

Question 12

definition of dealer

Answer 12

more that $500. buys sells or negotiates transport of animals for research

Question 13

definition of animal

Answer 13

live or dead dog, cat, non-human primate, guinea pig, hamster, rabbit, aquatic mammal, or any other warm blooded animal that is used or is intended for use in research. Exludes: birds, Rattus, and Mus bred for use in research

Question 14

composition of IACUC under AWA

Answer 14

3 members, one must be veterinarian and one non-affiliated members (no research personnel)

Question 15

job of IACUC

Answer 15

conduct inspections of all animal study areas at least every 6 months, report should be signed by quorum and include minority views, file report with IO. deficiencies w/ timetable. program review q 6 months with minority views.

Question 16

requirements of protocol review

Answer 16

1. identify species and number to be used

Question 17

requirements for surgical procedures

Answer 17

1. use aseptic technique with sterile instruments

Question 18

definition of adqueate veterinary care

Answer 18

availability of appropriate facilities, personnel, equipment, and services. appropriate methods to prevent, control, diagnose, and treat diseases and injuries and provide emergency veterinary care.

Question 19

Pain category B

Answer 19

animals used for breeding, conditioning or being held

Question 20

Pain category C

Answer 20

research will only include very brief pain or distress

Question 21

Pain category D

Answer 21

appropriate anesthesia and analgesia is provided for distressful and painful procedures

Question 22

Pain category E

Answer 22

Painful procedures are being performed w/o appropriate anesthesia or analgesia

Question 23

law establishing the public health services policy

Answer 23

Health Research Extension Act 1985

Question 24

The public health services policy is adminstered by:

Answer 24

OLAW under NIH under PHS

Question 25

how often must the PHS assurance be refiled

Answer 25

typically 5 years but may be less depending on OLAW

Question 26

PHS category 1

Answer 26

have AAALAC accredation

Question 27

PHS category 2

Answer 27

do not have AAALAC accredation

Question 28

definition of animal by PHS

Answer 28

all live vertebrate animals

Question 29

in addition to PHS what does OLAW use for standards

Answer 29

Guide for the care and use of laboratory animals

Question 30

composition of IACUC under PHS

Answer 30

5 members 1-veterinarian 2- non affiliated member 3- scientist 4 non-scientist

Question 31

Function of IACUC under PHS

Answer 31

1. review institutional program q6 months

Question 32

What should be involved in protocol review under PHS

Answer 32

1. avoid or minimize animal pain/discomfort

Question 33

What should be included in the program description

Answer 33

1. list of every component of institution to be included

Question 34

how long should records be kept under PHS and USDA

Answer 34

duration of activity plus three years

Question 35

record keeping requirements of IACUC under PHS

Answer 35

1. copy of assurance

Question 36

what needs to be in annual report to OLAW

Answer 36

any change in institutional category

Question 37

US government principles for utilization and care of laboratory animals

Answer 37

1. transportation, care and use is in accordance with AWA

Question 38

CIOMS

Answer 38

council for international organizations of medical sciences

Question 39

differences between CIMOS and US principles

Answer 39

advancement and knowledge requires animal research

Question 40

import and export regulations are overseen by

Answer 40

USDA APHIS for those animals that can carry diseases that infect livestock

Question 41

CITES

Answer 41

convention of international trade in endangered species of wild fauna and flora

Question 42

CITES in US is administered by

Answer 42

Department of Interior

Question 43

CITES category I

Answer 43

endagered species

Question 44

CITES category II

Answer 44

may become endangered if trade is not regulated

Question 45

CITES category III

Answer 45

any species within a countries jurisdiction that they want to regulate

Question 46

biohazadorous substances are regulated by

Answer 46

OSHA

Question 47

chemical hazadorous substances are regulated by

Answer 47

OSHA, DEA, EPA

Question 48

radioactive substances are regulated by

Answer 48

Nuclear Regulatory Commission (NRC)

Question 49

regulations governing recombinant DNA

Answer 49

DHHS, NIH Guidelines for research involving recombinant DNA molecules. IBC institutional biosafety commission at institutions overseen by RO regulatory official/ biosafety officer