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ACLAM study sets > BB Ch 2 > Flashcards

BB Ch 2 Flashcards

1
Q

AWA of 1966

A

licensing of dealers of dogs and cats. treatment before and after research

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2
Q

AWA of 1970

A

expanded to include regulated animals to include teaching, exhibition, wholesale pet industry, zoos. standards of care during research and includes more species

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3
Q

AWA of 1976

A

transportation guidelines

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4
Q

AWA of 1985

A

expanded to include IACUC, develop a national agriculture library, training of personnel

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5
Q

AWA of 1990

A

expanded to include holding period regulations

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6
Q

Fiscal year under AWA

A

Oct 1st to Sept 30

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7
Q

Annual report for AWA is due?

A

by Dec 1st

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8
Q

What should be in annual report to AWA/USDA

A
  1. assure professionally acceptable standards were followed 2. each investigator considered alternatives
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9
Q

when can exceptions to standards of care be issued?

A
  1. for health reasons. veterinarian can approve exemption that must be reviewed every 30 days unless it is a permenant condition
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10
Q

What type of information should the NAL provide

A

1) info pertaining to employee training

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11
Q

Who enforces AWA

A

USDA thru APHIS

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12
Q

definition of dealer

A

more that $500. buys sells or negotiates transport of animals for research

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13
Q

definition of animal

A

live or dead dog, cat, non-human primate, guinea pig, hamster, rabbit, aquatic mammal, or any other warm blooded animal that is used or is intended for use in research. Exludes: birds, Rattus, and Mus bred for use in research

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14
Q

composition of IACUC under AWA

A

3 members, one must be veterinarian and one non-affiliated members (no research personnel)

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15
Q

job of IACUC

A

conduct inspections of all animal study areas at least every 6 months, report should be signed by quorum and include minority views, file report with IO. deficiencies w/ timetable. program review q 6 months with minority views.

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16
Q

requirements of protocol review

A
  1. identify species and number to be used
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17
Q

requirements for surgical procedures

A
  1. use aseptic technique with sterile instruments
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18
Q

definition of adqueate veterinary care

A

availability of appropriate facilities, personnel, equipment, and services. appropriate methods to prevent, control, diagnose, and treat diseases and injuries and provide emergency veterinary care.

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19
Q

Pain category B

A

animals used for breeding, conditioning or being held

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20
Q

Pain category C

A

research will only include very brief pain or distress

21
Q

Pain category D

A

appropriate anesthesia and analgesia is provided for distressful and painful procedures

22
Q

Pain category E

A

Painful procedures are being performed w/o appropriate anesthesia or analgesia

23
Q

law establishing the public health services policy

A

Health Research Extension Act 1985

24
Q

The public health services policy is adminstered by:

A

OLAW under NIH under PHS

25
Q

how often must the PHS assurance be refiled

A

typically 5 years but may be less depending on OLAW

26
Q

PHS category 1

A

have AAALAC accredation

27
Q

PHS category 2

A

do not have AAALAC accredation

28
Q

definition of animal by PHS

A

all live vertebrate animals

29
Q

in addition to PHS what does OLAW use for standards

A

Guide for the care and use of laboratory animals

30
Q

composition of IACUC under PHS

A

5 members 1-veterinarian 2- non affiliated member 3- scientist 4 non-scientist

31
Q

Function of IACUC under PHS

A
  1. review institutional program q6 months
32
Q

What should be involved in protocol review under PHS

A
  1. avoid or minimize animal pain/discomfort
33
Q

What should be included in the program description

A
  1. list of every component of institution to be included
34
Q

how long should records be kept under PHS and USDA

A

duration of activity plus three years

35
Q

record keeping requirements of IACUC under PHS

A
  1. copy of assurance
36
Q

what needs to be in annual report to OLAW

A

any change in institutional category

37
Q

US government principles for utilization and care of laboratory animals

A
  1. transportation, care and use is in accordance with AWA
38
Q

CIOMS

A

council for international organizations of medical sciences

39
Q

differences between CIMOS and US principles

A

advancement and knowledge requires animal research

40
Q

import and export regulations are overseen by

A

USDA APHIS for those animals that can carry diseases that infect livestock

41
Q

CITES

A

convention of international trade in endangered species of wild fauna and flora

42
Q

CITES in US is administered by

A

Department of Interior

43
Q

CITES category I

A

endagered species

44
Q

CITES category II

A

may become endangered if trade is not regulated

45
Q

CITES category III

A

any species within a countries jurisdiction that they want to regulate

46
Q

biohazadorous substances are regulated by

A

OSHA

47
Q

chemical hazadorous substances are regulated by

A

OSHA, DEA, EPA

48
Q

radioactive substances are regulated by

A

Nuclear Regulatory Commission (NRC)

49
Q

regulations governing recombinant DNA

A

DHHS, NIH Guidelines for research involving recombinant DNA molecules. IBC institutional biosafety commission at institutions overseen by RO regulatory official/ biosafety officer

ACLAM study sets (22 decks)

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