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URN Biweekly 1 > Primary Glomerular Disease- Herrera > Flashcards

Primary Glomerular Disease- Herrera Flashcards

1
Q

synonyms include: primary glomerulonephritis, primary glomerulopathy

A

primary glomerular disease

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2
Q

5 yr old w/ nephrotic syndrome

A

Minimal Change disease

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3
Q
A

minimal change disease

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4
Q

protein specific—> albumin!!!

A

Minimal change disease

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5
Q

to treat MCD:

A

steroids

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6
Q

lipids in PCT

A

minimal change disease

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7
Q

effacement of podocytes

A

minimal change disease

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8
Q
A

effacement of podocytes

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9
Q
A

minimal change disease

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10
Q

45 yr old w/ reflux and nephrotic syndrome

A

FSGS (focal and segmental glomerulosclerosis)

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11
Q
A

FSGS

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12
Q

sclerosis of some glomeruli and parts of them; middle aged adults; non-selective proteinuria

A

FSGS

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13
Q

L
middle
R

A

L: FSGS
Middle: normal
R: collapsing type FSGS

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14
Q
A

FSGS

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15
Q
A

FSGS

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16
Q

19 yr old + for HIV

A

FSGS collapsing variant

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17
Q
A

collapsing variant FSGS

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18
Q
A

collapsing variant, FSGS

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19
Q

58 yr old male w/ colon carcinoma

A

membranous glomerulopathy

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20
Q

older adults
primary and secondary causes
PLA2R

A

membranous glomerulopathy

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21
Q

immune complex mediated (IgG and C3)
thickening of glomerular capillary wall/ subepithelial deposits of immune complexes
spikes

A

membranous glomerulopathy

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22
Q

wall thickening

A

membranous glomerulopathy

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23
Q

reaction of GBM around immune complexes

A

SPIKES

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24
Q
A

spikes; membranous glomerulopathy

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25
Q
A

membranous glomerulopathy

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26
Q
A

immune complex deposits; membranous glomerulopathy

27
Q

stages of immune complex deposits

A
  1. on top of membrane
  2. spikes
  3. w/in membrane
  4. disappear
28
Q
A

spikes

29
Q

spikes and IgG and C3; immune complex deposits

A

membranous glomerulopathy

30
Q
A

immune complex deposits; membranous glomerulopathy

31
Q

56 yr old female w/ nephritic syndrome; RBC casts

A

membranoproliferative glomerulonephritis (MPGN)

32
Q

nephrotic and nephritic syndrome

A

MPGN

33
Q

MPGN type I deals with

A

immune complexes

34
Q

MPGN type II deals with

A

C3 (alternative complement pathway)

35
Q

more than 2 mesangial cells seen

A

MPGN

36
Q

hep B and C (mainly C)
SLE
malignant tumors
can cause this

A

secondary type I MPGN

37
Q
A

MPGN

38
Q
A

MPGN

39
Q
A

type I MPGN

40
Q

(dense deposit disease); C3

A

MPGN type II

41
Q

very rare; dense membrane (C3)

A

MPGN type II

42
Q

25 yr old male w/ hematuria which occurs associated with infections

A

IgA nephropathy

43
Q

mesangium expanded; patient has hematuria

A

IgA nephropathy

44
Q

mesangial areas proliferating

A

IgA nephropathy

45
Q

IgA stained

A

IgA nephropathy

46
Q

deposits inside mesangium

A

IgA nephropathy

47
Q
A

IgA nephropathy

48
Q

17 yr old w/ nephritic syndrome after skin infection 2 weeks ago

A

acute proliferative glomerulonephritis

49
Q

diffuse proliferation of glomerular cells; influx of leukocytes

A

acute proliferative glomerulonephritis

50
Q

IgG and C3 immune complex deposits in subepithelial after having infection

A

acute proliferative glomerulonephritis

51
Q

hematuria; 2 weeks after infected with strep

A

poststrep glomerulonephritis

52
Q
A

proliferative/poststrep glomerulonephritis

53
Q

“starry sky” (IgG and C3)

A

acute poststrep/proliferative glomerulonephritis

54
Q

HUGE subepithelial immune complexes

A

acute poststrep/proliferative glomerulonephritis

55
Q

HUMPS

A

acute poststrep/proliferative glomerulonephritis

56
Q
A

acute proliferative/poststrep glomerulonephritis

57
Q

70 yr old female w/ rapid development of renal failure/acute kidney injury

A

rapidly progressive glomerulonephitis

58
Q

example of rapidly progressive glomerulonephritis

A

Goodpasture’s

59
Q

IgG and C3 (anti-GBM Ab’s)

A

rapidly progressive glomerulonephritis

60
Q
A

rapidly progressive glomerulonephritis

61
Q
A

RPGN

62
Q

ex of type I anti-GBM

A

goodpastures

63
Q
A

rapidly progressive glomerulonephritis (anti-GBM)

64
Q

what to do for this patient

A

kidney transplant

URN Biweekly 1 (21 decks)

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