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URN Biweekly 1 > Primary Glomerular Disease- Herrera > Flashcards

Primary Glomerular Disease- Herrera Flashcards

1
Q

synonyms include: primary glomerulonephritis, primary glomerulopathy

A

primary glomerular disease

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2
Q

5 yr old w/ nephrotic syndrome

A

Minimal Change disease

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3
Q
A

minimal change disease

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4
Q

protein specific—> albumin!!!

A

Minimal change disease

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5
Q

to treat MCD:

A

steroids

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6
Q

lipids in PCT

A

minimal change disease

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7
Q

effacement of podocytes

A

minimal change disease

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8
Q
A

effacement of podocytes

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9
Q
A

minimal change disease

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10
Q

45 yr old w/ reflux and nephrotic syndrome

A

FSGS (focal and segmental glomerulosclerosis)

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11
Q
A

FSGS

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12
Q

sclerosis of some glomeruli and parts of them; middle aged adults; non-selective proteinuria

A

FSGS

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13
Q

L
middle
R

A

L: FSGS
Middle: normal
R: collapsing type FSGS

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14
Q
A

FSGS

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15
Q
A

FSGS

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16
Q

19 yr old + for HIV

A

FSGS collapsing variant

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17
Q
A

collapsing variant FSGS

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18
Q
A

collapsing variant, FSGS

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19
Q

58 yr old male w/ colon carcinoma

A

membranous glomerulopathy

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20
Q

older adults
primary and secondary causes
PLA2R

A

membranous glomerulopathy

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21
Q

immune complex mediated (IgG and C3)
thickening of glomerular capillary wall/ subepithelial deposits of immune complexes
spikes

A

membranous glomerulopathy

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22
Q

wall thickening

A

membranous glomerulopathy

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23
Q

reaction of GBM around immune complexes

A

SPIKES

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24
Q
A

spikes; membranous glomerulopathy

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25
membranous glomerulopathy
26
immune complex deposits; membranous glomerulopathy
27
stages of immune complex deposits
1. on top of membrane 2. spikes 3. w/in membrane 4. disappear
28
spikes
29
spikes and IgG and C3; immune complex deposits
membranous glomerulopathy
30
immune complex deposits; membranous glomerulopathy
31
56 yr old female w/ nephritic syndrome; RBC casts
membranoproliferative glomerulonephritis (MPGN)
32
nephrotic and nephritic syndrome
MPGN
33
MPGN type I deals with
immune complexes
34
MPGN type II deals with
C3 (alternative complement pathway)
35
more than 2 mesangial cells seen
MPGN
36
hep B and C (mainly C) SLE malignant tumors can cause this
secondary type I MPGN
37
MPGN
38
MPGN
39
type I MPGN
40
(dense deposit disease); C3
MPGN type II
41
very rare; dense membrane (C3)
MPGN type II
42
25 yr old male w/ hematuria which occurs associated with infections
IgA nephropathy
43
mesangium expanded; patient has hematuria
IgA nephropathy
44
mesangial areas proliferating
IgA nephropathy
45
IgA stained
IgA nephropathy
46
deposits inside mesangium
IgA nephropathy
47
IgA nephropathy
48
17 yr old w/ nephritic syndrome after skin infection 2 weeks ago
acute proliferative glomerulonephritis
49
diffuse proliferation of glomerular cells; influx of leukocytes
acute proliferative glomerulonephritis
50
IgG and C3 immune complex deposits in subepithelial after having infection
acute proliferative glomerulonephritis
51
hematuria; 2 weeks after infected with strep
poststrep glomerulonephritis
52
proliferative/poststrep glomerulonephritis
53
"starry sky" (IgG and C3)
acute poststrep/proliferative glomerulonephritis
54
HUGE subepithelial immune complexes
acute poststrep/proliferative glomerulonephritis
55
HUMPS
acute poststrep/proliferative glomerulonephritis
56
acute proliferative/poststrep glomerulonephritis
57
70 yr old female w/ rapid development of renal failure/acute kidney injury
rapidly progressive glomerulonephitis
58
example of rapidly progressive glomerulonephritis
Goodpasture's
59
IgG and C3 (anti-GBM Ab's)
rapidly progressive glomerulonephritis
60
rapidly progressive glomerulonephritis
61
RPGN
62
ex of type I anti-GBM
goodpastures
63
rapidly progressive glomerulonephritis (anti-GBM)
64
what to do for this patient
kidney transplant

URN Biweekly 1 (21 decks)

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