Pathology Terminology ILA

Question 1

one differentiated cell type is replaced with another cell type

Answer 1

metaplasia

Question 2

“new growth”

Answer 2

neoplasia

Question 3

lack of cellular differentiation (“to form backward”

Answer 3

anaplasia

Question 4

disordered growth (preneoplastic)

Answer 4

dysplasia

Question 5

increase in number of cells resulting in increased mass of organ

Answer 5

hyperplasia

Question 6

specialized functional tissue of an organ

Answer 6

parenchyma

Question 7

marked variation in size and shape of cancer cells

Answer 7

pleomorphism

Question 8

involving some glomeruli

Answer 8

focal

Question 9

involving all glomeruli

Answer 9

diffuse

Question 10

involving part of glomerular tuft

Answer 10

segmental

Question 11

involving total glomerular tuft

Answer 11

global

Question 12

lobular appearance of capillary loop architecture

Answer 12

lobular

Question 13

relatively acellular areas of mesangial matrix expansion

Answer 13

nodular

Question 14

obliteration of capillary loop and increased matrix

Answer 14

glomerular sclerosis

Question 15

proliferation of parietal epithelial cells

Answer 15

crescent

Question 16

projections of glomerular BM intervening b/t subepithelial immune deposits

Answer 16

spikes

Question 17

proliferation of mesangial and/or endothelial cells and infiltrating inflammatory cells; filling up and distending capillary lumens

Answer 17

endocapillary proliferation

Question 18

area of necrosis that stains brick red w/ eosin due to denatured proteins and fibrin

Answer 18

fibrinoid necrosis

Question 19

descriptive of glassy, smooth-appearing material

Answer 19

hyaline

Question 20

hyaline-appearing insudation of plasma proteins

Answer 20

hyalinosis

Question 21

produced by insudation of plasma proteins from the circulation into glomerular structures

Answer 21

insudative lesions

Question 22

pyknotic and fragmented nuclei

Answer 22

Karyorrhexis

Question 23

stalk region of capillary loop w/ mesangial cells surrounded by matrix

Answer 23

mesangial area

Question 24

b/t glomerular BM and podocyte

Answer 24

subepithelial

Question 25

b/t endothelial cells and glomerular BM

Answer 25

subendothelial

Question 26

double contour of glomerular BM due to massive subendothelial deposits

Answer 26

Tram-track

Question 27

thick, rigid appearance of capillary loop due to massive subendothelial deposits

Answer 27

wire loop

Question 28

description encompassing possible treatment-sensitive lesions

Answer 28

activity

Question 29

description of probable irreversible lesions

Answer 29

chronicity

Question 30

discontinuous flecks of staining producing a granular pattern; seen along capillary loop

Answer 30

granular

Question 31

smooth continuous staining; seen along capillary loop

Answer 31

linear

Question 32

flattening of foot processes so they cover basement membrane w/ loss of slit diaphragms

Answer 32

foot process effacement

Question 33

small extensions of visceral epithelial cells w/ villus-like appearance

Answer 33

microvillus transformation