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Infeto > Polyomaviridae > Flashcards

Polyomaviridae Flashcards

1
Q

Características gerais

A

DNA
Nu
Icosaédrica
Tem 2 tipos : JC e BK

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2
Q

Epidemiologia

A

Vírus normalmente adquiridos na infância, que ficam latentes no rim - imunssupressão = reativa - virúria - POSTERIORMENTE virémia

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3
Q

Vírus BK : Clínica

A

Polyomavirus-associated nephropathy (PVAN) - principal agente
Cistite hemorrágica - transplantados de MO

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4
Q

Vírus JC : Clínica

A

Progressive multi focal leukoencephalopathy - imunodeprimidos (HIV, transplantes)
Polyomavirus-associated nephropathy (PVAN)

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5
Q

Vírus JC : Diagnóstico

A

PCR LCR (Leucoencefalopatia multifocal)

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6
Q

Vírus BK : Diagnóstico

A

Nefropatia associada ao poliomavirus :

  • citologia urina- pesquisa de células de Decoy (sensível mas pouco específico)
  • carga viral na urina PCR (sensível, especificidade variável) - rastreio
  • carga viral no sangue (+ específico) - confirmação
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Infeto (33 decks)

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