Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Y2 Revision > Physiology - Dermatology > Flashcards

Physiology - Dermatology Flashcards

1
Q

what is the largest organ in the body?

A

skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the outermost layer of skin called?

A

epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which type of epithelium makes up the epidermis?

A

stratified squamous epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which layer of skin is deep to the epidermis?

A

dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

which tissue type makes up the dermis?

A

connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

which germ layer forms the epidermis?

A

the ectoderm

forms the periderm that becomes the skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

which germ layer forms the dermis?

A

the mesoderm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

in foetal skin development, which layers are formed after 16 weeks?

A 
keratin layer 
granular layer 
prickle cell layer 
basal layer 
dermis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

which cell makes up most of the epidermis?

A

keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

true or false: the basal layer of the skin is metabolically active

A

true

contains lots of intermediate filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

name three epidermal cells

A

melanocytes
langerhans cells
merkel cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

where are melanocytes derived from?

A

the neural crest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are melanocytes?

A

pigment producing dendritic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what layer of skin are melanocytes found in?

A

the basal layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what do melanocytes do?

A

convert tyrosine to melanin pigment and load colour onto adjacent keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what colour is eumelanin?

A

brown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what colour is pheomelanin?

A

red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

which disease is caused by loss of melanocytes?

A

vitiligo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

where are langerhans cells derived from?

A

bone marrow

20
Q

what are langerhans cells?

A

antigen presenting cells

21
Q

where are langerhans cells found?

A

the prickle cell layer of the skin

22
Q

what are merkel cells?

A

mechanoreceptors that aid sensation

23
Q

where are merkel cells found?

A

between keratinocytes and nerve fibres

24
Q

what are the three phases of growth of a hair folicle?

A

anagen
catagen
telogen

25
Q

what is the dermo-epidermal junction?

A

the interface between the dermis and the epidermis

26
Q

give an example of an inherited skin fragility caused by a mutation in a protein in the DEJ

A

epidermolysis bullosa complex in young children

27
Q

give two examples of acquired skin fragility

A

dermatitis herpetiformis

bullous pemphigoid

28
Q

what do fibroblasts in the dermis produce?

A

procollagen

elastin

29
Q

what does procollagen become?

A

collagen

30
Q

true or false: the blood vessel supply to skin is greater than its metabolic need

A

true

31
Q

which nerve receptors sense pressure in the skin?

A

pacinian corpuscles

32
Q

which nerve receptors sense vibration in skin?

A

meissner’s corpuscles

33
Q

what do free nerve endings provide sense for in the skin?

A

temperature

pain

34
Q

which inherited condition arises due to overgrowth of nerve endings?

A

neurofibromatosis

35
Q

list the three main secretory glands in the skin

A

eccrine
apocrine
sebaceous

36
Q

what do eccrine glands secrete?

A

sweat

37
Q

what do apocrine glands secrete?

A

odorous fluid

38
Q

what do sebaceous glands secrete?

A

moisturiser

39
Q

which areas of the body have a high concentration of sebaceous glands?

A

head
neck
chest

40
Q

what is the significance of the melanin cap on basal cells?

A

absorbs UV rays to protect DNA in the cells nuclei

41
Q

which vitamin does skin metabolise?

A

vitamin D

42
Q

true or false: 20% of thyroxine conversion to triiodothyronine is done in peripheral tissues such as skin

A

false

80%

43
Q

which cells help protect the skin from UV rays?

A

melanocytes

44
Q

what is the ratio of melanocytes to basal cells?

A

1 to 10

45
Q

where is the papillary dermis found?

A

the uppermost layer of the dermis

Y2 Revision (95 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions