Buzzwords Flashcards
which enzyme builds up in porphyria cutanea tarda?
uroporphyrinogen decarboxylase
which porphyria is associated with a child with tingling/burning skin in direct sunlight?
erythropoietic protoporphyria
what is the first line treatment for acne vulgaris?
benzoyl peroxide
what is the first line treatment for acne rosacea?
topical metronidazole
which enzyme builds up in acute intermittent porphyria?
PBG deaminase
what skin condition has a stuck on appearance and looks like a brain?
basal cell papilloma
what skin condition is associated with coeliac disease?
dermatitis herpetiformis
what condition causes ash leaf spots, epilepsy and peringum slceroma?
tuberous sclerosis
what condition causes honey-coloured crusting?
impetigo
what condition causes small, umbilicated, translucent papules that look fluid filled but are solid?
molluscum contagiosum
what condition causes a heliotrope rash?
dermatomyositis
what condition causes target lesions?
erythema multiforme
what condition is acanthosis nigricans associated with?
addison’s disease
what is the most common bone tumour?
osteosarcoma
a painful arc suggests damage to which rotator cuff muscle?
supraspinatus
what nerve supplies the trapezius?
spinal accessory nerve
what is used to treat shaft of femur fractures?
thomas splint
which biologic causes reactivation of latent TB?
infliximab
what does tingling in the ring and pinky fingers suggest?
cubital tunnel syndrome
what is the first line treatment for necrotising fasciitis?
surgical debridement
which rheumatoid drug causes black, tarry stool?
NSAIDs
which rheumatoid drugs are nephrotoxic?
gold
penicillamine
visual loss, oral and genital ulcers suggest which disease?
behcet’s syndrome
which fracture typically produces a dinner fork deformity?
colles fracture
which structures may be damaged in a colles fracture?
median nerve
extensor pollicis longus
carpal bones
which fingers feel funny in carpal tunnel syndrome?
thumb
index finger
middle finger
half of the ring finger
how many x-ray views are taken for a scaphoid fracture?
two obliques
AP
lateral
a patient presents with bone pain, deformity and deafness, what is the likely differential?
paget’s disease
name three side effects of methotrexate
bone marrow suppression
liver cirrhosis
pneumonitis
when is methotrexate contrainidcated?
pregnancy
name two side effects of sulfalazine
rash
oligospermia
name two side effects of hydroxychloroquine
retinopathy
corneal deposits
name four side effects of prednisolone
cushing’ syndrome
osteoporosis
impaired glucose tolerance
cataracts
name two side effects of gold and penicillamine
proteinuria
nephropathy
what disease produces a pencil in cup appearance on x-ray?
psoriatic arthritis
what disease causes wrist drop?
radial nerve palsy
what syndrome classically causes arthritis, uveitis and urethritis?
reiter’s syndrome
damage to which nerve causes foot drop?
common fibular nerve
what is another name for the common fibular nerve?
peroneal nerve
how is an intracapsular hip fracture managed?
hemiarthroplasty
what does a sagging rope sign suggest?
AVN
what does an onion-peel sign suggest?
ewing’s sarcoma
what does sunray spiculation on x-ray suggest?
osteosarcoma
what does popcorn calcification on x-ray suggest?
chondrosarcoma
what does a soap bubble appearance on x-ray suggest?
giant cell tumour
what does a rosary bead sign suggest?
polyarteritis nodosa
what does a shepherd’s crook deformity suggest?
fibrous dysplasia
how do you treat endometrial polyps?
myomectomy
which insulin do you give once a day?
basal (long acting)
i.e. Lantus
which diabetic drug is weight neutral?
DPP-IV inhibitor
e.g. sitagliptin
what does strawberry milkshake blood suggest?
hyperlipidaemia
describe the calcium, phosphate and ALP levels in paget’s disease
calcium normal
phosphate normal
ALP high
which hormone forms the basis of pregnancy tests?
hCG
which hormone tests for fertility?
progesterone
describe the calcium, phosphate and ALP levels in osteomalacia
calcium low
phosphate low
ALP high
where is the site of spermatogenesis?
seminiferous tubules
which cells, acted on by LH, secrete testosterone?
leydig cells
which cells, acted on by FSH, enhance spermatogensis?
sertoli cells
what disease causes catecholamines in urine, headaches and hypertension?
pheochromocytoma
what causes moon face?
cushing’s disease
what causes orphan annie nuclei?
papillary thyroid cancer
what causes psammoma bodies?
papillary thyroid cancer
what causes anosmia and GnRH deficiency?
kallman’s syndrome
at what age should a child have a social smile?
six weeks
at what age can a child build a tower of three bricks and enjoy picture books?
eighteen months
which artery provides oxygenated blood in the foetus?
placental vein
what is a recent vaccine introduced in children?
rotavirus
what chromosome is affected in edward’s syndrome?
eighteen
what chromosome is affected in patau syndrome?
thirteen
what chromosome is affected in down syndrome?
twenty one
what does the ADHD triad consist of?
hyperactivity
impulsivity
inattention
what does the autism triad consist of?
communication
behaviour
language
what happens as a result of compression of CN VII in the facial canal?
bell’s palsy
which syndrome is due to reactivation of VZV in the geniculate ganglion of CN VII?
ramsay hunt syndrome
list the factors that make up the centor criteria
no cough
fever
cervical lymphadenopathy
tonsillar exudate
what does fluid level behind the ear drum/retracted drum suggest?
otitis media with effusion
what does difficulty at school and hearing loss suggest?
glue ear
what does a feeling of fullness in the ear suggest?
meniere’s disease
what does a loss of corneal reflex with sensorineural hearing loss suggest?
vestibular schwannoma
what does bilateral vestibular schwannoma in a child suggest?
neurofibromatosis type II
what does cheesy ear discharge suggest?
cholesteatoma
what does saddle nose suggest?
wegener’s granulomatosis
what motor neuron disease is associated with optic neuritis?
multiple sclerosis
what does LR6 mean?
lateral rectus is supplied by CN VI
what does SO4 mean?
superior oblique is supplied by CN IV
what does AO3 mean?
recti, levator palpebrae superioris and sphincter pupillae are all supplied by CN III
what does a cherry red spot on the macula suggest?
central retinal artery occlusion
what does a teardrop sign suggest?
blow out fracture
what does failure to adduct in the affected eye and nystagmus in the abducting eye suggest?
internuclear ophthalmoplegia
an issue with medial longitudinal fasiculus
what does “curtain coming down” suggest?
amaurosis fugax
what does “curtain coming down” longer than five minutes suggest?
retinal detachment
what do flashes and floaters suggest?
retinal detachment
what do gritty eyes suggest?
bacterial conjunctivitis
what do watery eyes and enlarged preauricular lymph nodes suggest?
viral conjunctivitis
what does a loss of red reflex and a red eye suggest?
haemorrhage
what does neovascularization and haemorrhage suggest?
wet ARMD
what causes follicular conjunctivitis?
chlamydia
what causes pinpoint pupils?
opiate overdose
what causes “down and out” eyes?
CN III palsy
what causes roth spots?
infective endocarditis
what causes brushfield spots?
down’s syndrome
what dauses drusen?
dry ARMD
what is the first line treatment fo BPH?
alpha blockers
i.e. tamsulosin
what is the first line investigation for hydrocele?
doppler USS with colour
which glomerulonephritis is associated with henoch-schonlien purpura?
IgA nephropathy
true or false: membranous nephropathy causes malignancy
true
what is the official name for viagra?
sildenafil
where does the bulbourethral gland lie?
posterior to the membranous urethra
splitting of which structure would prevent seminal fluid from entering the urethra?
bladder sphincter
what covers the testes?
tunica vaginalis
true or false: peritoneal dialysis causes weight gain
true
which vessel gives rise to the gonadal arteries?
abdominal aorta
which vessel gives rise to the right gonadal vein?
IVC
which vessel gives rise to the left gonadal vein?
left renal vein
what causes cannonball metastasis?
renal cell carcinoma that metastasises to the lungs
what causes a “sea anemone” sign?
transitional cell carcinoma
what organism causes foul smelling urine?
proteus sp.
what causes muddy brown casts?
acute tubular necrosis
what causes a “potato tumour”?
testicular seminoma
what causes a blue dot sign?
hydatid of morgagni
what causes an apple-green birefringence congo red stain?
amyloidosis