MODY Flashcards
what does MODY stand for?
mature onset diabetes of the young
what inheritance pattern does MODY usually follow?
autosomal dominant
is MODY insulin dependent?
no
what is the age of onset of MODY?
before 25
what are the two main distinct types of MODY?
transcription factor mutations
glucokinase mutations
at what age does glucokinase mutation related MODY onset?
birth
at what age does transcription factor mutation related MODY onset?
adolescence/young adulthood
true or false: glucokinase mutation related MODY involves unstable hyperglycaemia
false
stable hyperglycaemia
true or false: glucokinase mutation related MODY has better prognosis than transcription factor mutation related MODY
true
true or false: neonatal diabetes requires insulin treatment within the first 3 months of life
true
which drug class is good for transcription factor mutation related MODY?
sulphonylureas