MODY Flashcards

1
Q

what does MODY stand for?

A

mature onset diabetes of the young

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2
Q

what inheritance pattern does MODY usually follow?

A

autosomal dominant

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3
Q

is MODY insulin dependent?

A

no

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4
Q

what is the age of onset of MODY?

A

before 25

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5
Q

what are the two main distinct types of MODY?

A

transcription factor mutations

glucokinase mutations

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6
Q

at what age does glucokinase mutation related MODY onset?

A

birth

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7
Q

at what age does transcription factor mutation related MODY onset?

A

adolescence/young adulthood

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8
Q

true or false: glucokinase mutation related MODY involves unstable hyperglycaemia

A

false

stable hyperglycaemia

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9
Q

true or false: glucokinase mutation related MODY has better prognosis than transcription factor mutation related MODY

A

true

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10
Q

true or false: neonatal diabetes requires insulin treatment within the first 3 months of life

A

true

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11
Q

which drug class is good for transcription factor mutation related MODY?

A

sulphonylureas

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