Pharmacology - Respiratory Flashcards

1
Q

_______ is an inflammatory disorder of the airways and causes coughing, wheezing, breathlessness, and chest tightness

A

Asthma

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2
Q

COPD encompasses two major diseases:

A

emphysema and chronic bronchitis

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3
Q

_______ is irreversible

A

COPD

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4
Q

________is reversible

A

Asthma

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5
Q

labored or difficult breathing

A

dyspnea

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6
Q

You can assess the severity of asthma with a ________ to measure ________

A

peak flow meter

peak expiratory flow rate

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7
Q

PEFER

A

Peak expiratory flow rate

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8
Q

What does MDI stand for?

A

Metered dose inhaler

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9
Q

How long should the patient wait in between different inhalers

A

5 minutes

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10
Q

How can asthma medication be administered to children?

A

nebulizer

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11
Q

What is a SABA?

A

short-acting beta agonist or bronchodilators

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12
Q

What should a patient do after using a corticosteroid inhaler?

A

rinse mouth

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13
Q

What are some corticosteroid inhalers?

A

Qvar, Pulmicort, Flovent

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14
Q

_______ is used for long-term control of moderate to severe asthma

A

leukotriene inhibitors

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15
Q

________ may be used for mild persistent or more sever asthma

A

mast cell stabilizer

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16
Q

_______ causes relaxation of air-way smooth muscle and is structurally similar to caffeine

A

xanthine derivatives

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17
Q

_________is a mechanism for clearing the airways of excess secretions and foreign materials.

A

coughing

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18
Q

______are agents that suppress coughing.

A

antitussives

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19
Q

What are the two principle site of action of antitussives

A
  1. CNS depression of the cough centre in the medulla. (cough reflex)
  2. Suppression of nerve receptors within the respiratory tract.
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20
Q

________ is the “gold standard” of antitussives.

A

codeine

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21
Q

_______ is a CNS depressant and has a drying effect on the mucosa

A

codeine

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22
Q

What are the side effects of codeine?

A

nausea, drowsiness, dizziness, constipation.

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23
Q

________is also used as an antitussive.

A

dextromethorphan

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24
Q

___________decrease the thickness and stickiness of mucous, decreasing viscosity and increasing expiration of mucous

A

expectorants

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25
What is the most commonly used expectorant?
guaifenesin
26
________is derived from tree bark extract and is a common component of cough and cold remedies.
guaifenesin
27
What does guaifenesin do?
loosens phlegm (mucus) and thins bronchial secretions to make coughs productive and rid the respiratory tract of mucous
28
What are some side effects of guaifenesin?
vomiting, nausea, GI upset and drowsiness
29
_________stimulates the alpha-adrenergic receptors of the vascular smooth muscle.
decongestants
30
Sympathetic nervous system stimulation causes ____________
increased heart rate and blood pressure and heightened CNS stimulation
31
Decongestants’ should not be taken if the patient is using other drugs to treat any of the following conditions:
Diabetes Heart disease Hypertension Hyperthyroidism
32
What are some side effects of decongestants?
``` Anxiety CNS stimulation (inability to sleep) Dizziness Headache Increased heart rate ```
33
What is the most used decongestant?
Pseudoephedrine (Sudafed)
34
_________products must now be kept as schedule 2 in the province of Alberta.
Pseudoephedrine
35
Two types of drugs block the histamine receptors:
H1 - respiratory | H2 - GI
36
_______occurs when antihistamines penetrate the blood-brain barrier.
sedation
37
H1 blockers have many uses including:
Allergies, Insomnia, Cough Control, relief of hay fever
38
_______ is inhalation of fluids from the mouth and throat
aspiration
39
_________ is provoked by airborne allergens
asthma
40
____________ is a condition in which the inner lining of the bronchial airways becomes inflamed, causing the expiration of air from the lungs to be obstructed
bronchitis
41
_______ is an agent that causes the mucus membrane to shrink, allowing the sinus cavities to drain
decongestant
42
_______ is an agent that decreases the thickness and stickiness of mucus
expectorant
43
_________ is a device that delivers a specific amount of medication in a puff of compressed gas.
MDI
44
_______ is a device used in the administration of inhaled medications, uses air flowing past a liquid to create a mist
Nebulizer
45
Cigarette smoke contains more than ______ chemical compounds
4000
46
How many chemical compounds in cigarettes are carcinogens?
60
47
________-is the addictive drug in tobacco
nicotine
48
________damage and destroy the small hairs lining the airways. These small hairs are used to clean your airways, and when destroyed, it leaves your lungs vulnerable to irritants and cancer causing chemicals.
Phenols
49
What is TB?
Tuberculosis
50
_______most commonly attacks the lungs, but can also affect the central nervous system, the lymphatic system, the circulatory system, the genitourinary system, bones, joints and even the skin.
Tuberculosis
51
_____% of the cases are pulmonary TB
75
52
What are some symptoms of TB?
chest pain, coughing up blood, and a productive, prolonged cough for more than three weeks
53
How is TB spread?
aerosols
54
What does CF stand for?
Cystic Fibrosis
55
What is RDS?
Respiratory Distress Syndrome
56
______occurs in newborns during the first few hours of life. Its characteristics – acute asphyxia with hypoxia and acidosis – can inhibit pulmonary surfactant production
RDS
57
In adults RDS is called _______
ARDS or Acute Respiratory Distress Syndrome
58
________an irreversible lung disease characterized by destruction of the alveoli, allows air to accumulate in organs and tissue
Emphysema
59
________ is the oversecretion of thick mucus clogs the respiratory system
Cystic Fibrosis
60
What are some "rescue" medications?
ventolin, bricanyl, berotec
61
What are some "non-rescue" medications?
servent, oxeze
62
What are some "controller" medications?
Flovent, Qvar, Pulmicort
63
_______ are usually "controller" medications?
corticosteroids