Compounding Flashcards
What are Extemporaneous Compounds?
Compounds needed on demand
What are Bulk Compounds?
Compounds that are made in bulk for future use
What must adhere to standards?
Non-sterile compounds
What must adhere to standards?
Sterile compounds
Give three examples of sterile products.
injection, infusion or application to the eye
Which ACP standard must we follow when compounding?
Standard 10
What is PPE?
Personal Protective Equipment - gloves, mask, lab coat etc…
Before starting any compound that the pharmacy technician look up_______for the ingredients they are using.
MSDS
What is a torsion?
Weighs small amount
What is a counter scale?
Weighs amounts up to 5kg
What must weights be transferred with?
Forceps
What type of spatulas are there?
Stainless steel, plastic, or hard rubber
What have wide tops and wide bases and taper from top to bottom?
Conical Graduates
What have a narrow diameter that is the same from top to bottom?
Cylindrical Graduates (graduated cylinder)
What are graduates made of?
Glass or Plastic
How many mL’s do graduates usually hold?
5-1000mL
What can be used for measurements of volumes of liquid less than 1.5 mL?
Pipette
The markings on a measuring device called?
Calibration
What is a hydrophilic base?
Creams
What is a hydrophobic base?
Ointments
What is it called to mix a liquid and a powder to form a suspension or solution?
Reconstitution
What is a solution that has a medication dissolved into a base of alcohol, water and sugar?
Elixer
What is an ingredient that is dissolved into a solution?
Solute
What is the greater part of a solution that is capable of dissolving another substance?
Solvent
What is a solution in which solid particles do not dissolve into the base and must be shaken before using?
Suspension
What is a sugar-based liquid?
Syrup
What is a base solution of alcohol?
Tincture
What is the act of reducing a substance to small, fine particles?
Comminution
What is the act of combining two (or more) substances together?
Blending
What is when two solids are mixed together that result in a liquid being formed?
Eutectic
What the process of passing mixtures through a filter or filter medium?
Filtration
What is the process of incorporating small amounts of drugs into lotions, creams, and ointments?
Geometric Dilution
What would refer to the base ointment, cream, or lotion?
Levigation Agent
Capable of being mixed and staying mixed without separation (usually used in reference to liquids)
Miscible
_______means to add to the quantity to achieve the specific quantity required for the final product
QS (Quantity Sufficient)
_______________is to disperse fine powder evenly in a liquid (the fine powder does NOT dissolve in the liquid)
Suspend
__________the process reducing solids into fine particles by grinding or rubbing them in a mortar with a pestle
Trituration
This is a fluid or liquid medium that serves as a carrier for medication in liquid dosage forms
Vehicle
What are the different kinds of liquid compounds?
Solutions
Suspensions
Emulsions
What is a clear liquid preparation that all the active ingredients have been dissolved into the vehicle?
Solution
What can be used externally and internally?
Solutions
What does Aqueous mean?
Water based
What does Alcoholic mean?
Alcohol based
What does Hydro alcoholic mean?
Water and Alcohol based
What types of solutions are there?
Syrups Elixirs Aromatic waters Extracts Fluid extracts Tincture Spirits Irrigation solutions Parenteral solutions Enemas
What label must always be on suspensions?
Shake well before use
The particles suspended are not soluble in the vehicle and are referred to as _______
Suspensoids
What is a mixture of water and oil that should be made with an emulsifier to bind the two together?
Emulsion
What does w/o mean?
Water in a oil base
What does o/w mean?
Oil in a water base
What are the two kinds of enemas?
Retention enema
Evacuation enema
What are the different vehicles used for solvents?
aqueous, hydro-alcoholic, and alcohol
___________ contains less than the maximum amount of solute that a solvent can hold at specific temperature?
Unsaturated
_______________contains the maximum amount of solute that a solvent can hold at specific temperature
Saturated
__________contains more than the maximum amount of solute that a solvent can hold at specific temperature
Supersaturated
__________ is the maximum amount of solute dissolved in solvent at specific temp or barometric pressure
Solubility
What are the 6 solid dosage forms?
Capsule Tablet Powders Lozenges Suppositories Sticks
What is it called when one compounds a capsule?
Encapsulation
What are the different types of capsules?
Hard and Soft
What is a hard capsule?
A capsule containing powder or liquid. They can be fast release or slow and can be separated into two pieces.
What is a soft capsule?
Usually are standard release
What are the two parts of the capsule?
Body and cap
What are the different sizes of capsules?
5 (smallest) - 000 (largest)
These capsules can be pulled apart and sprinkled onto food, these capsules contain small beads
Spansules
The objective is to have the same amounts of ingredients in each tablet; called ________
Content Uniformity.
SR
Slow Release
CD
Controlled Diffusion
LA
Long Acting
XL
Extra Long
XR
Extended Release
SA
Sustained Action
TR
Time Released
TD
Time Delay
___________to be put in between the cheek pouch and the gums and let dissolve
Buccal administration
IA
Intra arterial
KVO
Keep Vein Open
mEq
milliequivilent
LAH
Laminar Air Flow Hood
PFS
Prefilled syringe
ISO
Internationalized organization for standardization
CPS
Compounded Sterile Product
IPA
Isopropyl Alcohol
IVP
Intravenous Push
IM
Intramuscular
IVPB
Intravenous Piggy Back
amp
Ampoule
BSC
Biological Safety Cabinet
PPE
Personal Protective Equipment
TPN
Total Parenteral Nutrition
SC
Subcutaneous
NS
Normal Saline (0.9%)
D5
Dextrose 5%
LR
Lactated Ringers
K
Potassium
MgSO4
Magnesium Sulfate
MVI
Multivitamins
NTG
Nitroglycerin
PCN
Penicillin
K
Potassium
SWFI
Sterile Water For Injection
Can parenteral solutions be frozen?
YES
Medication being used must only be checked in the ante room before compounding?
NO, must be check during the proceedure
CPS
Compounded Sterile Products
Venting needle size:
25G 5/8’
True or False, the maximum dose for SC injection is 3ml?
FALSE, that is to much
Class 5 air quality?
3520
Class 7 air quality?
352,000
Class 8 air quality?
3,520,000
What is BUD?
Beyond Use Date
CAI
Compounding Aseptic Isolator
CACI
Compounding Aseptic Containment Isolator
LAFW
Laminar Airflow Workbench
Where do we garb up?
Anteroom
DCA
Direct Compounding Area
SDV
Single Dose Vial
MDV
Multi Dose Vial (can be punctured 5 times)
PVC
Polyvinyl Chloride Bags
LVP
Large Volume Parenteral
PEP
Post Exposure Prophylaxis
HEPA
High Efficiency Particulate Air
HEPA eliminates how much particles?
99.97%
What must not be mixed together because it causes precipitate?
Calcium Gluconate and Potassium Phosphate
Where can a TPN line be placed?
subclavian vein or peripheral vein
TPN room temp
30 hours
TPN fridge temp
9 days
TPN freezer temp
45 days
What is PPN?
Peripheral Parenteral Nutrition