Pharmacology Flashcards
1
Q
t1/2 equation
A
0.693 x Vd / Cl
2
Q
How many t 1/2 to clear drug
A
5
3
Q
Vd equation
A
Vd= Dose/ [drug]plasma
[drug]plasma is blood plasma conc.
4
Q
Dosage rate equation
A
Dr= [drug]plasmass x Cl
5
Q
Steady state equation
A
[drug]plasmaSS= Dr/cl
6
Q
what is pKa
A
Half ionised, half unionised
7
Q
what is pKi
A
the binding affinity to receptors
Higher value = higher affinity
8
Q
What is EC50
A
Conc. of drug inducing response that’s 50% of the maximum (Emax)
9
Q
What is Emax
A
Maximum effect of a drug
10
Q
A
