Pathology of the Heart Part 2 Flashcards

1
Q

does dilated cardiomyopathy cause systolic or diastolic dysfunction?

A

primarily systolic
some diastolic dysfunction

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2
Q

what is restrictive cardiomyopathy?

A

severe and extensive or patchy fibrous thickening of the endocardium

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3
Q

what are the classifications of myocarditis?

A

suppurative
lymphocytic/lymphoplasmacytic
eosinophilic
granulomatous
pyogranulomatous
hemorrhagic

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4
Q

what can directly effect cardiac myocytes and cause cardiac hypertrophy?

A

hyperthyroidism

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5
Q

what can cause protozoal myocarditis?

A

Trypanosoma cruzi
Toxoplasma gondii
Sarcocystis spp
Neospoea caninum
Encephalitozoan cuniculi

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6
Q

what does the myocardium look like with fungal myocarditis?

A

extensively pale tan

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7
Q

what are some parasites that cause myocarditis in sheep?

A

Taenia spp
Trichinella spp

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8
Q

what are some metastatic causes of cardiac neoplasia?

A

lymphoma
melanoma
carcinoma

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9
Q

what are some primary causes of cardiac neoplasia?

A

hemangiosarcoma
rhabdomyoma
rhabdomyosarcoma
myxoma
schwannoma/neurofibroma
chemodectoma

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10
Q

what is lymphoma in cattle often associated with?

A

bovine leukosis virus infection

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11
Q

how can you tell there is metastatic neoplasia, not primary neoplasia, in the heart?

A

multiple, separate nodules

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12
Q

what are some causes of cardiomyopathies (secondary)?

A

heritable
nutritional
toxic
physical injury/shock
endocrine
infectious
neoplasia

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13
Q

what do the fibers look like with dilated cardiomyopathy?

A

attenuated, wavy myofibers
atrophy
interstitial fibrosis

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14
Q

what does dilated cardiomyopathy look like grossly?

A

ventricular dilation
globoid appearance
rounded apex
collapse of ventricles

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15
Q

what is usually impacted by restrictive cardiomyopathy?

A

left ventricle usually
enlarged left atrium

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16
Q

what patterns in cats are seen with restrictive cardiomyopathy?

A

endomyocardial fibrosis or irregular trabecular/broad bands bridging left ventricle free wall and interventricular septum

17
Q

what hereditary secondary cardiomyopathies cause DCM?

A

contractile protein defects
ion channel defects
X-linked muscular dystrophy

18
Q

what nutritional deficiencies can cause secondary cardiomyopathies?

A

selenium/vitamin E
potassium
copper
thiamine
magnesium

19
Q

what can cause secondary cardiomyopathies due to physical injury and shock?

A

CNS lesions and CNS trauma
gastric dilation and volvulus
electrical defibrillation
hemorrhagic shock