Pathology of Brain Tumours Flashcards
1
Q
What is cerebral perfusion pressure?
A
Mean arterial pressure - intracranial pressure
2
Q
What are the causes of raised ICP?
A
Inflammation (meningitis, encephalitis, abscess)
Vascular (haemorrhage, swelling)
Tumours
Hydrocephalus
3
Q
What are the effects of intracranial space occupying lesions?
A
Amount of tissue increases
Raises ICP
Herniation between spaces
4
Q
What pathology can explain the Glasgow coma scale?
A
Squeeze on cortex and brainstem
5
Q
What pathology can explain pupillary dilatation?
A
Squeeze and stretch on cranial nerve 3
6
Q
What pathology explains localising signs?
A
Squeeze on decussation of corticospinal tracts and posterior columns
7
Q
What is ischaemic penumbra?
A
Tumours squeeze tissue and cause local ischaemia
