Patho: Microscopic Findings

Question 0

HX disseminated TB
MICRO burnt out lymph nodes with multiple pathogens; no granulomatous formation
IMAGING brain tumor consistent with lymphoma

Answer 0

AIDS

Question 1

PE Hand with clawlike deformity–MICRO Extensive deposition of collagen in the dermis; hyaline thickening of dermal vessels
IMMUNO Anti centromere and topoisomerase

Answer 1

Scleroderma

Question 3

Man dies of unknown multiorgan dz that lead to renal failure death
MICRO stains mahogany brown in some areas; focal deposits are seen on mesangial matrix stains with Congo red; all deposits ARE EXTRACELLULAR; spleen looked like it had sago; What is the disease entity?

Answer 3

Apple green; amyloidosis

Under polarized light congo red would stain apple green

Question 4

What is the most common finding aortic dissection?

Answer 4

Cystic medial degeneration

Question 5

Hyaline arteriolosclerosis in a patient with a BP of 160/90 is most probably due to?

What would the diagnosis if onion skinning was seen instead?

Answer 5

Benign hypertention

Malignant hypertension. this is hyperplastic arteriolosclerosis

Question 6

A patient has the following findings on his thoracic aorta, pathy loss of medial fibers, tree barking of intima and atheroslcerosis, what is the most probable dx?

Answer 6

Syphilitic or luteic aorta

Question 7

PE: Cyanotic Obese 60/M
MICRO: Reid’s index of 1, with hyperemic and swollen mucosal lining of the ariways covered with mucinous secretions

Answer 7

Bronchitis; COPD Blue bloater

Question 8

HX: Dx case of CF and repeated bouts Klebsiella pneumonia
Patient dies of overwhelming pneumonia. Besides findings consistent with pneumonia what else would you expect to find upon autopsy of his lungs?

Answer 8

Bronchi dilated up to the pleura. Bronchiectasis