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VMS 2004 > Pasteurella > Flashcards

Pasteurella Flashcards

1
Q

What kind of pathogens are pasteurellaceacae?

A
  • opportunistic pathogens
  • contain many different organism
  • normal inhabutants of the URT and GIT
  • 31 genera in the family
  • oxidase posituve
  • faculative anaerobe
  • cocci shaped
  • no flagella
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2
Q

How would you culture them?

A
  • Blood agar
  • cultured at 37 degrees
  • anaerobically for 24-48 hours
  • some can lyse red blood cells
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3
Q

What are the main manifestations of disease?

A
  • Respiratory tract (URT/ pneumonia)
  • Septicaemia
  • Trauma-associated conditions (mouth microorganisms are incoulated by bites, rough feed or via licking of surgical wounds)
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4
Q

What toxins are produced by pasteurella?

A
  • RTX toxins-group of virulence factors
  • Urease
  • Pmt P
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5
Q

What is bovine respiratory disease also known as?

A

cattle pneumonia/ shipping fever

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6
Q

What is the pathobiology of BRD?

A

pathogenesis involves stress factors, with or without viral infection- interacting to supress host defence mechanisms

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7
Q

What is the challenge of detecting BRD?

A
  • limited sensitivity and appearance
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8
Q

Who does atrophic rhinitis mainly affect?

A

Mainly affects piglets at 3-8 weeks of age

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9
Q

What are the two types of atrophic rhinitis?

A
  • Non-progressive atrophic rhinitis- caused by bordatella bronchioseptica
    (mild and transient with little effect on growth and performance)
  • progressive atrophic rhinitis- caused by toxigenic pasteurella multocida
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10
Q

What are the clinical signs of atrophic rhinitis?

A
  • Poor growth
  • Sneezing, coughing inflammation of the lacrimal duct
  • nasal haemorrhage
  • lateral deviation or shortening of the upper jaw
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11
Q

How does rabbit pasteurelliosis spread in companion animals

A

mating, fighting, stress in the animal (pregnancy, lactation, poor husbandry)

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12
Q

Where does pasteurelliosis live in comopanion animals?

A
  • lives asymptomatically in the mouth
  • may cause an often fatal pneumonia
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13
Q

What are the symptoms of pasteurelliosis in guinea-pigs?

A
  • Direct contact, grooming, aerosol, possible insect bites
  • many are asymptomatic carriers
  • can present with fever, weight loss, conjunctivitis and pneumonia
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14
Q

What is the function of adhesins on pasteurella?

A
  • colonise the host
  • are then turned off when they are inside the host
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15
Q

What is the function of RTX toxins?

A
  • lyse bovine erythrocytes
  • activate leukocytes
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16
Q

What is the function of PMT

A

mainly damage in rhinitis

17
Q

Why may BRD not be detected in cattle?

A

The observed clinical signs are not specific for BRD

18
Q

What causes wry neck in rabbits?

A

Middle or inner ear infection

19
Q

Where does pasteurelliosis live in dogs/ cats?

A

Lives asymptomatically in the mouth

20
Q

What does pasteutelliosis cause in dogs/ cats?

A

May cause a pneumonia that is often fatal
- can be spread via bite wounds or aerosols

21
Q

How can guinea-pigs get pasteurelliosis?

A

Direct contact, Grooming, aersols or insect bites

22
Q

What may a guinea pig with pasteurelliosis present with?

A
  • Fever, weight loss, conjunctivitis, pneumonia, pyometra
23
Q

What gives immunity against septicaemia and fowl cholera?

A

Circulating antibodies

24
Q

What is the best way to control pasteurella

A
  • Regular testing
  • Good environmental conditions
25
Q

What is the best supportive treatment for pasteurelliosis?

A

The use of non-steroidal anti-inflammatory drugs

26
Q

What does PMT stand for?

A

P.Multocida Toxin

causes a lot of the damage in atrophic rhinitis

27
Q

What is the function of urease?

A

Converts urea into ammonia
* attracts phagocytes and then inhibits them

28
Q

What stressors may cause transmission of P.multocida?

A
  • Overcrowding
  • Temperature
  • Poor Nutrition
29
Q

Name 4 ways of treating patseurella

Not NSAIDS

A
  • Separate infected animals
  • Treat concurrent infection
  • Improve environmental conditions
  • Antibiotics
30
Q

What causes avian cholera?

A

P.multocida

31
Q

What clinical signs would you see with Infectious Coryza
Avibacterium paragallinarum?

A
  • Decreased activity
  • Nasal discharge
  • Sneezing
  • Facial Swelling
32
Q

How would you diagnose pasteurella in guinea-pigs?

A

Culture or PCR

33
Q

What are some ways of diagnosing pasteurella?

A
  • PCR
  • LAMP assay
  • Serology
  • Culture
  • Biochemical testing

VMS 2004 (34 decks)

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