Burkholderia Flashcards
1
Q
What type of bacteria is burkholderia mallei?
A
- Gram negative
- Non-motile
- encapsulated
- non-sporulated
1
Q
What is burkholderia mallei known as in the skin?
A
Farcy
2
Q
What kind of conditions does burkholderia thrive in?
A
Humid to wet conditions
3
Q
What species are the most susceptible to burkholderia?
A
Equids
* Horses = chronic
* Donkeys = acute
4
Q
What is the pathogenesis of burkholderia?
A
- Enters the body either via ingestion or inhalation
- Phagocytosed by macrophages
- Escapes into the cytoplasm and proliferates
- bacteria moves via actin filaments
5
Q
What are the four ways you could diagnose Burkholderia?
A
- Complement fixation
- PCR
- Bacteriology
- Mallein test (injection of antibodies)
6
Q
What is burkholderia pseudomallei?
A
- Gram negative
- non-sporulating
- motile
- faculative anaerobe
7
Q
Where is burkholderia pseudomallei found?
A
- Tropical areas
- Wet areas
8
Q
What are the three ways you can diagnose Burkholderia pseudomallei?
A
- PCR
- ELISA
- Bacterial Culture
9
Q
What is the mallein test?
A
Hypersensitivity Skin test against B.mallei
10
Q
What species are most susceptible to pseudomallei?
A
- Small ruminants
- Pigs
- Mice
11
Q
What type of inflammation is pseudomallei mainly?
A
Pyogranulomatous Inflammation
