Pastest Derm Flashcards

1
Q

Which classes of drugs are associated with Toxic epidermal necrolysis

A

Penicillins, NSAID’s, Steroids

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2
Q

Which DMARD can cause Toxic epidermal necrolysis

A

Methotrexate

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3
Q

Which Uricosuric drug can cause Toxic epidermal necrolysis

A

Allopurinol

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4
Q

Is Nikolsky’s sign negative or positive for Toxic epidermal necrolysis

A

Positive

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5
Q

What is Lupus Pernio and what disease is it pathognomic of

A

Large purple infiltrated nodules & plaque-like lesions on nose, cheeks, ears fingers and toes.
Pathognomic of Chronic Sarcoidosis

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6
Q

What is the most common cutaneous manifestation of TB

A

Lupus Vulgaris

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7
Q

What sort of infiltration will be seen in Lupus Vulgaris

A

Granulomatous

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8
Q

Which race is Pemphigus Vulgaris more common in

A

Jewish people

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9
Q

What smear is used for Pemphigus Vulgaris

A

Tzanck smear

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10
Q

What kind of nuclei will the acantholytic keratinocytes have in Pemphigus Vulgaris

A

Large Hyperchromatic Nuclei

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11
Q

A waxy yellow patch of ulceration on shins in diabetics?

A

necrobiosis lipoidica diabeticorum

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12
Q

What should you consider in a patient with Alopecia + Abnormal scalp skin

A

A possibility of Tinea Capitis

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13
Q

What is the treatment for Tinea Capitis

A

Oral Terbinafine

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14
Q

What is Panniculitis

A

Inflammation of subcutaneous fat e.g erythema nodosum

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15
Q

Name a disease where you would see Ichthyosis

A

Sarcoidosis

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16
Q

What is diagnosed using blue-green fluorescence on Wood’s light

A

Dermatophyte infection

17
Q

What drug can be given for Alopecia and how does it work

A

Minoxidil as it causes hypertrichosis

18
Q

Where on the body and in which race are keloid scars most common

A

Most frequently occur around the shoulders and chest

More common in people with darker skin

19
Q

Which porphyria doesn’t cause photosensitivity

A

Acute intermittent porphyria

20
Q

Are squamous cell carcinomas usually pigmented

A

Squamous cell carcinomas are not commonly pigmented

21
Q

What can be trialled for psoriasis if retinoid, topical steroids & phototherapy don’t work

A

Anti-TNF e.g etanercept

22
Q

What would make you think that a patient had pruritus due to iron deficiency

A

Thinning of the hair

23
Q

Which cancer can cause pruritis

A

Hodgkin’s lymphoma

24
Q

Which thyroid pathology can cause pruritis

A

Hyperthyroidism

25
Q

In Acne Vulgaris, what happens when Propionibacterium Acnes degrade sebum

A

Produce inflammatory fatty acids

26
Q

What is Acne vulgaris severity is directly related to

A

The degree of secretion of sebum

27
Q

Which cells in the epidermis make keratin

A

Basal Cells?

28
Q

Define Erythroderma

A

Any condition which causes over 90% of the skin to become inflamed, erythematous and scaly, could occur in psoriasis

29
Q

What are Koenen’s Tumours and which condition are they associated with

A

Periungal fibromas, seen in tuberous sclerosis

30
Q

What should symmetrical round lesions of eczema make you suspect

A

Nummular Dermatitis

31
Q

Which pathology tends to involve the nasolabial fold and demonstrates fine greasy scales with a pruritic erythematous rash

A

Seborrheic dermatitis

32
Q

What is Dovobet

A

A cream containing Calcitriol (vit D analogue) + Betamethasone (steroid)

33
Q

Erythema multiforme and lichen planus can be caused by which two liver conditions

A

Hep B and C

34
Q

Porphyria Cutanea Tarda can be associated with which GI condition

A

Hep C

35
Q

What diet change could exacerbate Lichen Planus

A

Spicy food

36
Q

Chronic venous ulcers associated with osteomyelitis are known as what

A

Marjolin’s ulcers

37
Q

Is a Marjolin ulcer malignant

A

No but can develop into squamous cell carcinomas