Pastest Derm Flashcards
Which classes of drugs are associated with Toxic epidermal necrolysis
Penicillins, NSAID’s, Steroids
Which DMARD can cause Toxic epidermal necrolysis
Methotrexate
Which Uricosuric drug can cause Toxic epidermal necrolysis
Allopurinol
Is Nikolsky’s sign negative or positive for Toxic epidermal necrolysis
Positive
What is Lupus Pernio and what disease is it pathognomic of
Large purple infiltrated nodules & plaque-like lesions on nose, cheeks, ears fingers and toes.
Pathognomic of Chronic Sarcoidosis
What is the most common cutaneous manifestation of TB
Lupus Vulgaris
What sort of infiltration will be seen in Lupus Vulgaris
Granulomatous
Which race is Pemphigus Vulgaris more common in
Jewish people
What smear is used for Pemphigus Vulgaris
Tzanck smear
What kind of nuclei will the acantholytic keratinocytes have in Pemphigus Vulgaris
Large Hyperchromatic Nuclei
A waxy yellow patch of ulceration on shins in diabetics?
necrobiosis lipoidica diabeticorum
What should you consider in a patient with Alopecia + Abnormal scalp skin
A possibility of Tinea Capitis
What is the treatment for Tinea Capitis
Oral Terbinafine
What is Panniculitis
Inflammation of subcutaneous fat e.g erythema nodosum
Name a disease where you would see Ichthyosis
Sarcoidosis
What is diagnosed using blue-green fluorescence on Wood’s light
Dermatophyte infection
What drug can be given for Alopecia and how does it work
Minoxidil as it causes hypertrichosis
Where on the body and in which race are keloid scars most common
Most frequently occur around the shoulders and chest
More common in people with darker skin
Which porphyria doesn’t cause photosensitivity
Acute intermittent porphyria
Are squamous cell carcinomas usually pigmented
Squamous cell carcinomas are not commonly pigmented
What can be trialled for psoriasis if retinoid, topical steroids & phototherapy don’t work
Anti-TNF e.g etanercept
What would make you think that a patient had pruritus due to iron deficiency
Thinning of the hair
Which cancer can cause pruritis
Hodgkin’s lymphoma
Which thyroid pathology can cause pruritis
Hyperthyroidism
In Acne Vulgaris, what happens when Propionibacterium Acnes degrade sebum
Produce inflammatory fatty acids
What is Acne vulgaris severity is directly related to
The degree of secretion of sebum
Which cells in the epidermis make keratin
Basal Cells?
Define Erythroderma
Any condition which causes over 90% of the skin to become inflamed, erythematous and scaly, could occur in psoriasis
What are Koenen’s Tumours and which condition are they associated with
Periungal fibromas, seen in tuberous sclerosis
What should symmetrical round lesions of eczema make you suspect
Nummular Dermatitis
Which pathology tends to involve the nasolabial fold and demonstrates fine greasy scales with a pruritic erythematous rash
Seborrheic dermatitis
What is Dovobet
A cream containing Calcitriol (vit D analogue) + Betamethasone (steroid)
Erythema multiforme and lichen planus can be caused by which two liver conditions
Hep B and C
Porphyria Cutanea Tarda can be associated with which GI condition
Hep C
What diet change could exacerbate Lichen Planus
Spicy food
Chronic venous ulcers associated with osteomyelitis are known as what
Marjolin’s ulcers
Is a Marjolin ulcer malignant
No but can develop into squamous cell carcinomas
