Cammy Diabetes Flashcards
Dysfunction of glucose regulation would favour HYPER/HYPOglycaemia?
Hyper
What 2 things does insulin stimulate and 2 things it inhibits
Stimulates Glucose transport into cells and Glycogenesis
Inhibits Glycogenolysis & Gluconeogenesis
What is insulitis
T-lymphocyte infiltrate into islets of Langerhans seen in T1DM
Which thyroid pathology can contribute to hypoglycaemia and why
Hypothyroidism as it prolongs the effects of insulin?
What is seen on histology of islets in T2DM
Amyloid depositions
Why is hyperkalaemia seen in DKA
Because of a lack of insulin and insulin normally drives potassium into cells
What is the holy trinity of DKA treatment
Fluid
Potassium
Insulin
Why is muscle mass typically low in Type 1 diabetes
Because unopposed glucagon action causes muscle to be degraded to release protein for gluconeogenesis
What is Sildenafil and what is it used to treat
Viagra lol
Used to treat erectile dysfunction in diabetics
Which drug is given for peripheral neuropathy
Duloxetine
What can be trialled as a treatment for gastroparesis in autonomic neuropathy
Metoclopramide can be trialled
4 types of diabetic neuropathy
Focal
Proximal
Autonomic
Peripheral
Which ratio is used to screen for diabetic kidney disease
Urinary Albumin: Creatinine ratio
The presence of what in the urine suggest a bad prognosis because it presents in late kidney disease
Microalbuminuria
