Pain Flashcards
1
Q
What is SCN9A?
A
An α subunit in voltage-gated Na+ channels
Found in nociceptive neurons
2
Q
What is allodynia?
A
Sensitisation to normally innocuous stimuli
3
Q
What are the two theories surrounding pain?
A
Specificity theory and convergence theory
4
Q
What are the two components of central pain pathways?
A
Sensory discriminative (what kind of pain it is and where) Affective-motivational (unpleasantness)
5
Q
Which tract is involved in the sensory discriminative central pain pathway?
A
Spinothalamic tract
6
Q
Does the affective-motivational pathway have topographic mapping?
A
Not really
7
Q
Which theory does the evidence point towards?
A
Specificity
8
Q
What is hyperalgesia?
A
Increased response to a painful stimuli
