Other Tumor Types Flashcards

1
Q

Cutaneous Hemangiosarcoma

A

UV light induced
Inguinal and epidermal (doesn’t penetrate dermis)

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2
Q

Who is most likely to get cutaneous Hemangiosarcoma?

A

Lightly-haired glabrous skin
Dalmatians, pits, boxers, beagles, whippets

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3
Q

What is the difference in biologic behavior for cutaneous and visceral hemgiosarcoms in dogs?

A

??

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4
Q

Where is primary visceral HSA mostly found?

A

Spleen
Liver, right atrium and skin
Anywhere there are Bvs
Most common cardiac tumor

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5
Q

Presentation of visceral HSA

A

RHF- ascites
Weakness, lethargy, collapse, anemia with pale mm, waxing and waning

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6
Q

Differential dx of splenic masses

A

Hematoma
Hyperplasia
2/3 malignant and 2/3 HSA

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7
Q

How do you dx Hemangiosarcoma

A

Histopathology*
Cytology (+ if malignant cells)
Imaging (hypoechic, cavitary)

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8
Q

Clin path changes with Hemangiosarcoma

A

Anemia: regen if old bleed, non with acute bleeding
Thrombocytopenia
DIC (Exposure of endothelium)
Schistocytes

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9
Q

EKG changes with Hemangiosarcoma

A

Electrical alternans
Small complexes

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10
Q

What predisposes to injection site carcinoma?

A

Multiple Ags in the same Vx
Killed Vx
Adjuvanted vx

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11
Q

Which Vx should you use to avoid ISS

A

Monovalent, non-adjuvated, only necessary Vx, admin SQ not IM

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12
Q

What is the surgical recommendation to get complete margins in ISS?

A

Avoid interscapular space
Distal limb (allow for amputation)
Tail (more distal)

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13
Q

Sx for ISS

A

GP MTR= 2-3m
Boarded surgeon= 14m
Amputation
MST= 2y

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14
Q

Recurrence rate after sx for ISS

A

40-70% with MTR 6m despite clean margins

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15
Q

Signalment of transitional cell carcinoma of the bladder

A

Older dogs
Females predisposed
Scotties, WHWT, wire-haired fox terrier, shelties, beagles

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16
Q

TCC

A

Trigone of bladder
Field effect
>50% have urethra involvement
Urinary obstruction

17
Q

Dx of TCC

A

Braf test: performed on free-catch urine combined sample 40mL and non invasive
FNA/traumatic catheter/sx: risk of seeding

18
Q

Tx/ prognosis of TCC

A

Piroxicam: 6m, PR: 15-20%
Piroxicam + CT: 1y, PR= 33%
Vinblastine: 5m
RT: obstruction, 6m

19
Q

Tx of AGASACA

A

Sx LNs: 2y with multiple Sx
Blind digital extirpation

20
Q

Massive hepatocellular carcinoma

A

Mass

21
Q

Diffuse hepatocellular carcinoma

A

Throughout the liver- met (more common, left lobe)

22
Q

Why do we not expect CT to work well for liver tumors?

A

More chemo resistant: the liver clears toxins so most CT agents are considered toxins

23
Q

What cats are predisposed to developing squamous cell carcinoma

A

White faced cats

24
Q

How do we tx SCC in cats

A

Sx, Cryotherapy, RT, ECT, Imiquamod, PDT
Sunscreen

25
Q

Prognosis fro cats with SCC?

A

Predisposed, high recurrence >60%
MST= 600 days