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Pharmacy > Oncology Pathophysiology > Flashcards

Oncology Pathophysiology Flashcards

1
Q

CEBPA

A

Favorable prognosis for AML

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2
Q

NPM-1

A

Favorable prognosis for AML

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3
Q

Flt 3 AML

A

Unfavorable prognosis

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4
Q

AML M3

A

15;17 translocation involving retinoic acid gene

Treat differently with all-trans retinoic acid (ATRA)

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5
Q

FLIPI, IPI criteria

Non-Hodgkin

A

High risk if 3 or more factors

Age>60
Clinical stage 3/4
Elevated LDH
Extranodal sites

FLIPI: hemoglobin

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6
Q

CLL

A

Over abundant B lymphocytes >40%

CD 19-23

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7
Q

Myeloid lymphoma

A

Blasts >20%

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8
Q

B cell non Hodgkin lymphoma

A

70% most common

Unimodal elderly

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9
Q

Hodgkin

A

Bimodal
Neck lymph nodes
B symptoms fever, night sweat, weight loss

BCL2 and c-myc genes

Fertility counseling

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10
Q

Cervical cancer

A

HPV 16, 18

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