Lung Cancer Therapeutics Flashcards
1
Q
Relapses SCLC
A
Single agent
Paclitaxel
Docetaxel
2
Q
Extensive (stage IV) SCLC
EPIC
A
EP
Or irinotecan + carboplatin
3
Q
Non-squamous NSCLC
A
Test for EGFR and ALK mutation
1) platinum doublet
Cisplatin & pemetrexed
4
Q
Squamous NSCLC
A
Cisplatin and gemcitabine
5
Q
Stage 3/4 NSCLC
EVVP
A
Chemo and radiation
Need radiosensitizer
Etoposide, vinblastine, vinorelbine, Paclitaxel with platinum
6
Q
Stage 4 metastatic
A
ECOG 0-2 platinum doublet
EVOG 3-4 best supportive care
7
Q
Limited (stage 1-3) Small cell lung cancer
Small EP
A
Etoposide & cisplatin (or carboplatin)
Need to hydrate if cisplatin
Carboplatin better if CHF and can’t handle hydration
8
Q
NSCLC EGFR+
A
Use erlotinib single agent
9
Q
NSCLC ALK+
A
1) crizotinib
2) ceritinib
10
Q
Which is more aggressive? Small or non small lung cancer
A
Small cell lung cancer
