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Pharmacy > IBD > Flashcards

IBD Flashcards

0
Q

Distal/left sided IBD

A

Mesalamine suppository, enema

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1
Q

Sulfasalazine

A

Supplement folic acid

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2
Q

Extensive IBD

A

Oral therapy

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3
Q

Rowasa

A

Mesalamine suppository

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4
Q

Pentasa

A

Slow release oral mesalamine, reaches the jejunum (released in small intestine and throughout entire colon)

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5
Q

Asacol

A

Delayed, pH dependent, enteric coated tablet

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6
Q

Lialda

A

Once daily enteric coated delayed release

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7
Q

Apriso

A

Extended release granules

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8
Q

Olsalazine

A

2 mesalamines, diarrhea

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9
Q

Balsalazide

A

Prodrug

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10
Q

Canasa

A

Mesalamine enema

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11
Q

Sulfasalazine, olsalazine, balsalazide

A

require bacteria to cleave into mesalamines

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12
Q

Hydrocortisone 5x dose methylprednisolone

A

Cortisone 5x dose prednisone

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13
Q

Corticosteroids

A

Supplement calcium and vitamin D

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14
Q

Immunomodulators

A

3rd line to ASA and steroids

Azathioprine, 6-mercaptopurine, MTX, CsA

Can measure 6-thioguanine for adherence

Phenotype TPMT for thiopurine effectiveness

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15
Q

Cyclosporine

A

Useful for unresponsive to steroid UC and fistulizing chrohns disease

Nephrotoxicity, bone marrow suppression

16
Q

Methotrexate

A

Induce clinical remission in CD and spare steroid usage

Low CBC-pancytopenia, hairloss, hepatotoxicity

17
Q

Infliximab

A

TNF alpha antibody

Pretreat with diphenhydramine or APAP for ADRs

Contraindicated in 3/4 heart failure

18
Q

Fistulizing CD

A

1) cyclosporine
2) infliximab
3) metronidazole
4) ciprofloxacin

19
Q

IBD CHF or respiratory disease

A

VTE prophylaxis w/LMWH or UFH

20
Q

UC remission maintenance

A

ASAs no steroids

Steroid dependent: Azathioprine

21
Q

Moderate/severe CD

A

PO steroid prednisone

Hospitalized - IV methylprednisolone

22
Q

CD remission maintenance

A

Azathioprine/ 6-MP first line

23
Q

Toxic megacolon

A

Aggressive fluid/electrolyte management

Avoid opiates/anticholinergics that slow the bowels

High dose steroids

24
Q

Anemia complication

A

Ferrous sulfate

25
Q

Osteoporosis complication

A

Calcium, vit D

Biphosphonate

26
Q

Mild/mod CD

A

ASA
Budesonide

Mod corticosteroids
If fail infliximab

Pharmacy (63 decks)

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