occupational lung disease Flashcards

1
Q

what is pneumoconiosis ?

A

an interstitial lung disease associated with inhalation of certain fibres initiating an inflammatory process and eventually leads to fibrosis of the lungs

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2
Q

what is the primary prevention of occupational lung diseases ?

A

reduce exposure

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3
Q

what is the primary exposure inn asbestos ?

A

during mining and milling

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4
Q

what are the secondary exposure causes of asbestos ?

A

manufacturing using asbestos as with pipe workers
paint and cloth production
brake lining
ship construction

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5
Q

what are the asbestos related lung diseases ?

A

pleural disease ( moat common )
asbestosis
bronchogenic carcinoma

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6
Q

what are the associated pleural diseases ?

A

pleural plaques
pleural effusion
diffuse pleural thickening
rounded atelectasis
mesothelioma

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7
Q

what do pleural plaques look like on chest x ray ?

A

localized thickening and calcifications along the level of the diaphragm

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8
Q

what is diffuse pleural thickening commonly confused with ?

A

mesothelioma

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9
Q

what is the differential diagnosis of rounded atelectasis ?

A

lung cancer (pseudocancer)

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10
Q

where is the affection in asbestosis ?

A

in the lower lung fields

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11
Q

what is heard on auscultation of asbestosis ?

A

bilateral, inspiratory rales

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12
Q

how does asbestosis look like on chest x ray ?

A

bilateral diffuse reticulonodular opacities and honeycombing

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13
Q

what is evident in the lung biopsy in asbestosis ?

A

barbell shaped fiber ( golden brown fusiform rods)

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14
Q

what is silicosis caused by ?

A

inhalation of silica dust

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15
Q

what occupations are associated with silicosis ?

A

mining
ceramic work
sandblasting
glass and pottery

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16
Q

what does the pathology look like in silicosis ?

A

silicotic nodules

17
Q

what does acute silicosis look like on a chest x ray ?

A

diffuse alveolar filling pattern with lower lung zone predominance

18
Q

what does chronic scoliosis look like on chest X ray ?

A

nodules that are found in the upper lung lobe
nodules eventually turn into Progressive massive fibrosis
eggshell calcification of lymph nodes

19
Q

what is the most characteristic findings on an X ray of chronic silicosis ?

A

eggshell calcification of lymph nodes

20
Q

what is silicosis most commonly complicated by ?

A

tuberculosis , must have a tuberculin skin test done

21
Q

what is the cause of coal worker pneumoconiosis ?

A

parenchymal lung disease due to inhalation and deposition of coal mine and dust

22
Q

what is NOT a common characteristic found in coal worker pneumoconiosis ?

A

crackles and clubbing

23
Q

what are the x ray findings in simple CWP ?

A

small rounded opacities in the upper zone

24
Q

what are the primary lesions of CWP ?

A

coal macules

25
Q

what can a coal macule eventually develop into ?

A

coal nodule

26
Q

what is caplan syndrome ?

A

rheumatoid pneumoconiosis
association of rheumatoid arthritis and workers who have breathed in silica or coal

27
Q

how to treat caplan syndrome ?

A

deal with RF alone and PMF alone

28
Q

what kind of pattern is observed in ILD ?

A

restrictive

29
Q

what kind of pattern is seen in COPD ?

A

obstructive pattern

30
Q

how can we tell the difference between restrictive and obstructive patterns ?

A

restrictive pattern the FEv1/FVC ratio remains unchanged
so we need to look at each element alone
whilst
obstructive patterns the ratio is decreased

31
Q

in what type of diseases do we see a decrease in DLCO ?

A

in obstructive lung diseases such as COPD

32
Q

when could there be an increase in DLCO ?

A

alveolar haemorrhage

polycythemia

33
Q

when is clubbing seen ?

A

toxic
hypoxic
malignant

34
Q

what is thee sign seen on HRCT that denotes rounded atelectasis ?

A

comet tail sign

35
Q

what do the pulmonary function tests look like in asbestosis ?

A

restrictive impairment
reduction in lung volumes
decreased DLCO

36
Q

what stain is used in the alveolar sputum sample in sarcoidosis ?

A

Prussian blue

37
Q

patients who have coal worker pneumoconiosis are at a greater risk of developing ?

A

COPD

38
Q

what is the onset of asbestosis after exposure to asbestos ?

A

prolonged latency period