ILD large group Flashcards
what are the acute presentations of sarcoidosis ?
lofgren syndrome
heerford-waldenstrom syndrome
what are the features of lofgren syndrome
BAEF
bilateral hilar adenopathy
erythema nodosum
arthralgia
fever
what are the features of heerford waldenstrom syndrome ?
anterior uveitis
fever
parotid enlargement
facial palsy
what is the first line of imaging in ILD ?
chest xray
what is the gold standard for imaging in ILD ?
HRCT
what are the 4 classifications of chest films in sarcoidosis ?
bilateral hilar lymphadenopathy
bilateral hilar lymphadenopathy + pulmonary disease
only pulmonary disease (reticulonodular shadows )
irreversible fibrossis and honey combing
what are the findings associated with sarcoidosis on HRCT ?
septal bleeding , nodules next to bronchovascular bundles
hilar LN on Xray
what is the first line treatment for sarcoidosis ?
prednisolone 0.5 mg/kg for 4-6 weeks , immunosuppressants can be used too
what does the BAL look like in sarcoidosis ?
lymphocytosis with raised CD4:CD8 ratio >2.5 is diagnostic
what does the BAL look like in IPF ?
high in neutrophils
what does the BAL look like in PLCH ?
high in langerhan cells
CD1a and s100 positive
what does the BAL look like in chronic eosinophilic pneumonia ?
above 50% in eosinophils
what is the difference in CD4:CD8 levels between sarcoidosis and hypersensitivity pneumonitis ?
sarcoidosis CD4:CD8 > 2.5
HP CD4:CD8 < 1
