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ICC1 > COPD - magda > Flashcards

COPD - magda Flashcards

1
Q

what are the obstructive airway diseases ?

A

bronchiectasis
asthma
emphysema
chronic bronchitis

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2
Q

what are the types of emphysema ?

A

centriacinar / centrilobular
panacinar / panlobular
distal / paraseptal

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3
Q

what type of emphysema causes clinical significant airway obstruction ?

A

centriacinar / centrilobular

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4
Q

what type off emphysema is seen in cigarette smokers ?

A

centriacinar emphysema

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5
Q

what type of emphysema is seen in alpha 1 antitrypsin patients ?

A

panacinar

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6
Q

some cases of spontaneous pneumothorax are caused by what type of emphysema ?

A

para-septal emphysema

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7
Q

which type of emphysema is clincially asymptomatic?

A

irregular emphysema

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8
Q

most common type of emphysema ?

A

irrregular

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9
Q

what is the most common type of asthma ?

A

atopic asthma

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10
Q

what type of hypersensitivity reaction is atopic asthma ?

A

type 1 IgE mediated hypersensitivity reaction

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11
Q

what are atopic asthmatic attacks often perceded by ?

A

allergic rhinitis
urticaria
eczema

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12
Q

what is status asthmaticus ?

A

severe paroxysms of asthma not responding to therapy and persisting for days and sometimes even weeks

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13
Q

which lobes of the lung are affected by bronchiectasis ?

A

bilateral lower lobes

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14
Q

what are the features of interstitial lung diseases ?

A

bilateral infiltrative pattern of small nodules
irregular lines or ground glass shadows
restrictive pattern on lung function test

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15
Q

what are the three major patterns in interstitial lung disease ?

A

fibrosing
granulomatous
smoking related

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16
Q

types of pneumoconiosis ?

A

coal duct - anthracosis
silica - silicosis
asbestos - asbestosis

17
Q

which key cell element is responsible foor the initiation and perpetuation of lung injury and fibrosis ?

A

macrophage

18
Q

what is the spectrum of coal worker pneumoconiosis ?

A

pulmonary anthracosis
simple coal workers pneumoconiosis - coal nodules
complicated coal worker pneumoconiosis - coalescence of coal nodules

19
Q

cause of silicosis ?

A

inhalation of crystalline silica - mainly quartz

20
Q

why is silicosis associated with an increased susceptibility to tuberculosis ?

A

silicosis causes depression of cell mediated immunity

21
Q

what are the effects of asbestosis ?

A

cellular and fibrotic lung reactions
tumor initiator and promoter

22
Q

what is the most common manifestation of asbestosis exposure ?

A

pleural plaques

23
Q

what is organic pneumoconiosis ?

A

the same as hypersensitivity pneumonitis

24
Q

what are the characteristic findings associated with sarcoidosis ?

A

elevated ACE and calcium levels
hilar LN involvement
skin , LN and kidney involvement

ICC1 (50 decks)

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