NPNs: Ammonia Flashcards
By product of AMINO ACID DEAMINATION
Ammonia
Converted to Urea in the Liver
Excreted in the Kidney
Ammonia
Clinical Applications:
- Assess and diagnose HEPATIC FAILURE AND HEPATIC COMA
- Diagnose Reye’s Syndrome
- Inherited Deficiencies of Urea Cycle
Ammonia
Patient has Increased CNS pH and GABA neutrotransmitter is inhibited
Hepatic Coma
Cirrhosis
Hepatitis
Reyes Syndrome
Chronic Renal Disease
Acetaminophen poisoning
Increased Level ammonia
Condition by which commonly occurs in children following aspirin medication after viral infection
Reye’s Syndrome
80% of Liver Function is nonfunctional
Liver Failure
Increased ammonia can lead to
Coma
Laboratory Method for Ammonia:
Specimen used in Ammonia
Chilled HEPARINIZED and EDTA Arterial Plasma
Specimen used in STAT for ammon
EDTA arterial specimen
The specimen for ammonia testing must be centrifuged at ____ within ___ minutes from collection and plasma is removed
4 deg celsius
20 minutes
Chilling of Heparinized sample is done using
Slurry Ice
It should be avoided by RMT and PX when testing for Ammonia
Smoking (False Increased)
- ISE
- Spectrophotometry
- Berthelot Reaction
- Nesslerization
Chemical Method for Ammonia
Ammonia + bromphenol blue =
Blue dye