Endrocrinology Flashcards
Chemical messengers in the body to produce biochemical changes; Increase level of activity of a process
Hormone
Major Function of Hormone
Feedback Mechanism
Feedback Mechanism consists of (2)
- Positive Feedback Mechanism
- Negative Feedback Mechanism
Decrease in the product; Increases the activity of the system and the production rate
Positive Feedback Mechanism
Increase in the product decreases the activity of the system and the production rate
Negative Feedback
- Each Hormone is produced in a specific Endocrine gland
- Hormones are released into blood circulation and carried to site of action as FREE hormone or bound to transport protein
- Each hormone acts at a specific site (target organs) to induce certain characteristics, biochemical changes
Characteristics of Hormone
Classification of Hormones by Tissue Origin:
TRH, CRF, GnRH
Hypothalamus
Classification of Hormones by Tissue Origin:
FSH
LH
GH
PRL
TSH
ACTH
Anterior Pituitary Gland
Classification of Hormones by Tissue Origin:
Vasopressin
Oxytocin
Posterior Pituitary Glans (Storage only)
Classification of Hormones by Tissue Origin:
Epinephrine
Norepinephrine
Adrenal Medulla
Classification of Hormones by Tissue Origin:
Cortisol
II-Deoxycortisol
Aldosterone
Adrenal Cortex
Classification of Hormones by Tissue Origin:
T3
T4
Calcitonin
Thyroid
Classification of Hormones by Tissue Origin:
PTH
Parathyroid
Classification of Hormones by Tissue Origin:
Insulin
Glucagons
Pancreas
Classification of Hormones by Tissue Origin:
Estrogens
Ovaries
Classification of Hormones by Tissue Origin:
Testosterone
other Androgens
Testes
Types of Hormone Actions:
Act directly upon themselves
Autocrine
Types of Hormone Actions:
Act adjuscent to the cells of origin
Paracrine
Types of Hormone Actions:
Acts within the cell of origin without exiting the cells
Intracrine
Types of Hormone Actions:
Secreted in one location and release into BLOOD CIRCULATION, binds to specific receptor to elicit action
Endocrine
Types of Hormone Actions:
Secreted in endocrine cells and remains in relation to plasma membrane
Acts on immediately adjascent cells by DIRECT CELL TO CELL contact
Juxtacrine
Types of Hormone Actions:
Endocrine cells and interacts with receptors of cells at distant site
SECRETED INTO DUCTS
Exocrine
Hormone Classification by Structure:
About 2/3 of hormones are proteins or peptides
Does not require transport proteins
Proteins/Peptides
Insulin, PTH, LH, FSH, TRH, ACTH, Prolactin, GH, Calcitonin, Glucagon, TSH. HCG
Hormone Classification by Structure:
Primarily involved in regulation of sexual development and characteristics ; Require Transport Protein
Steroid