Endocrine: Adrenal Gland Flashcards

1
Q

located above the kidney, shaped like pyramids
Maintain BP, Na, K, Glucose hemeostasis

A

Adrenal Gland

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2
Q

treated with exogenous hormone replacement

A

Hypofunction

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3
Q

Treated with supressive drugs and surgery

A

Hyperfunction

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4
Q

Adrenal composed of 2 Glands

A

Adrenal Cortex (OUTER)
Adrenal Medulla (INNER)

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5
Q

Arise from mesenchymal cells with 3 zone layer

A

Adrenal Cortex

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6
Q

3 zone layer of Adrenal Cortex

A
  1. Glomerulosa (G-cell)
  2. Fasciculata (F-cell)
  3. Reticularis (R-cell)
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7
Q

Mineralocorticoid
Aldosterone
Salt

A

Glomerulosa (G-cell) (10%

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8
Q

Glucocorticoids
Glucose
Cortisol

A

Fasciculata (F-cell) (75%)

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9
Q

DHEAS
Sex steroids

A

Reticularis (R-cell) (10%)

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10
Q

stimulate production of Epinephrine

A

Glucocorticoids

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11
Q

arise from neural crest

A

Adrenal Medulla

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12
Q

Major Hormones involved in Hypothalamic Pituitary Axis

A

ACTH and Angiotensin
CRH
Cortisol

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13
Q

Major Substrate precursor for Adrenal Cortex

A

Cholesterol

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14
Q

Cholesterol is derived from (2)

A
  1. from LDL
  2. from Acetyl CoA
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15
Q

Zonal Glomerulosa Urinary Metabolite

A

17-hydroxycorticosteroids

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16
Q

Zonal Reticularis Urinary Metabolite

A

17-ketosteroids