LIPIDS: Lipoprotein III

Question 1

NCEP Guideline Recommendations:

LDL Cholesterol:

Optimal
Near Optimal
Borderline High
High
Very High

Answer 1

Optimal <100
Near Optimal 100-129
Border line High 130 - 159
High 160 - 189
Very High >190

Question 2

NCEP Guideline Recommendations:

Total Cholesterol:

Desirable
Borderline High
High

Answer 2

Desirable < 200
Borderline High 200-239
High >240

Question 3

NCEP Guideline Recommendations:

HDL Cholesterol:

Positive Risk
Negative Risk

Answer 3

Positive Risk < 40
Negative Risk > 60

Question 4

NCEP Guideline Recommendations:

Triglycerides:

Normal
Borderline High
High
Very High

Answer 4

Normal <150
Borderline High 150-199
High 200-499
Very High >500

Question 5

NCEP Therapeutic Goals:

LDL
1. CHD is present
2. No CHD, 2 or more risk
3. No CHD, No Risk

Answer 5

1. < 100
2. < 129
3. < 159

Question 6

NCEP Therapeutic Goals:

Total Cholesterol

Answer 6

< 200

Question 7

NCEP Therapeutic Goals:

Triglycerides

Answer 7

< 150

Question 8

NCEP Therapeutic Goals:

HDL

Answer 8

> 60

Question 9

Frederickson Classification of Hyperlipidemias:

Increased Chylomicrons
Creamy Top Layer

Answer 9

Type I Hyperlipoproteinemia / Familial Hyperchylomicronemia

Question 10

Frederickson Classification of Hyperlipidemias:

Increased LDL ; Clear

Answer 10

Type IIa Hyperlipoproteinemia / Familial Hypercholestrolemia

Question 11

Frederickson Classification of Hyperlipidemias:

Increased LDL and VLDL ; Clear

Answer 11

Type IIb Hyperlipoproteinemia / Familial Combined Hypercholestrolemia

Question 12

Frederickson Classification of Hyperlipidemias:

Increased IDL ; Turbid

Answer 12

Type III hyperlipoproteinemia / Familial dysbetalipoproteinemia

Question 13

Frederickson Classification of Hyperlipidemias:

Increased VLDL

Answer 13

Type IV hyperlipoproteinemia / Familial Hyperlipemia

Question 14

Frederickson Classification of Hyperlipidemias:

Increased VLDL and Chylomicrons ; Creamy at top, Turbid Bottom

Answer 14

Type V hyperlipoproteinemia / Familial Hypertriglyceridemia

Question 15

Most common familial form of hyperlipoproteinemia

Answer 15

Type IIb Familial Combined Hyperlipidemia

• Apo B100 increased. HDL decreased.

Question 16

associated with VLDL and B100 overproduction in the liver

Answer 16

Hyperabobetalipoproteinemia

Question 17

Secondary Lipoproteinemia can be caused from

Answer 17

No Problem, My DM HOP

Nephrotic Syndrome
Pancreatitis
Myxedema
Diabetes Mellitus
Hypothyroidism
Obesity
Pregnancy

Question 18

Hypolipoproteinemias:

Decreased TC
Decreased Trig
LDL and Apo B100 ABSENT

Answer 18

Abetalipoproteinemia

Question 19

Hypolipoproteinemias:

Apo B100 and B48 are ABSENT
Low TC
Normal-Low Trig level

Answer 19

Hypobetalipoproteinemia

Question 20

Hypolipoproteinemias:

Severely Elevated Trig
Low HDL

Answer 20

Hypoalphalipoproteinemia

Question 21

Hypolipoproteinemias:

HDL absent
Mutation in ABCA1 gene on Chromosome 9

Answer 21

Tangier’s disease

Question 22

hardening and narrowing of arteries

Answer 22

Arteriosclerosis

Question 23

narrowing of arterial due to plaque build up ; deposition of cholesterol and Trigy

Answer 23

Atherosclerosis

Question 24

phytosterols are absorbed and accumulates in plasma and peripheral tissues

Answer 24

Sitosterolemia

Question 25

Transfer of Cholesterol esters are inhibited = Apo A1 increased

Answer 25

CETP deficiency

Question 26

Chylomicron’s retention disease

Answer 26

Anderson’s disease

Question 27

present in childhood with fat malabsorption and LOW PLASMA LIPIDS

Answer 27

Anderson’s disease

Question 28

Atherosclerotic cardiovascular disease + Type 2 DM

Answer 28

Metabolic Syndrome

Question 29

Metabolic Syndrome Risk Factors

Answer 29

HDL Decreased
LDL Increased
TRG Increased
Blood Glucose Inc
Blood Pressure Inc