Non specific animal resopnses Flashcards
list non- specific responses
- blood clotting
- skin
- wound repair
- inflammation
- mucous membranes
- expulsive reflexes
mucous membranes have…
goblet cells and ciliated epithelium
name 3 mucosal membranes
- respitory tracte
- gastrointestinal tracte
- genitourinary tracte
skin
- a layer of dead cells (uninhabitable for viruses)
- constant removal of dead skin makes it hard for pathogens to inhabit
Metabolic pathway to form fibrin (for blood clotting)
- damaged tissue activates platelets
- thrombin catalyses the reaction of soluble fibrogen to insoluble fibrin.
inability to form blood clots..
haemophillia
explain inflammatory response
- redness because capiliaries are swollen
- this is caused by histomines
- dialate blood vessels cause more tissue fluid to be releases into blood.
- cytokines released to attract white blood cells
Roles of cytokines
- cell signalling molecules
- attract white blood cells
- increase temperature
what does tissue fluid in swelling do?
- causes swelling and pain
Fever
higher than normal body temperature
effects of fever
- increases kinetic energy so white blood cells more likely to attack.
- some pathogen enzymes denature
opsonins
chemicals that bind to pathogen
interactions between opsonin and phagacytes
phagacytes contain receptors that bind to common opsonins
interferons
signalling chemicals that stimulate nearby cells to heighten their antiviral defences.
blood clotting cascade
platelets release thromboplastin
thromboplastin catalyses
Ca2+ + prothrombin —> thrombin
thrombin catalyses
Fibrogen ——> fibrin (insoluble)