Neuromuscular Drugs

Question 1

What neurotransmitter works at neuromuscular juntions?

Answer 1

ACh

Question 2

What kind of drug is Neostigmine?

Answer 2

Cholinesterase inhibitor

Question 3

What kind of drug is Pyridostigmine

Answer 3

Cholinesterase Inhibitor

Question 4

What are cholinesterase inhibitors used to treat?

Answer 4

Myeasthenia Gravis

Reverse Neuromuscular Blockade after surgery

Question 5

Name 2 cholinesterase inhibitors

Answer 5

Neostigmine

Pyridostigmine

Question 6

What drugs are used to make a neuromuscular blockade?

Answer 6

Veluronium (short procedures)

Pancruonium (long procedures)

Question 7

What are neuromuscular blocking drugs used for?

Answer 7

Surgery to block skeletal muscle contraction

ECT

Question 8

What is the mechanism of action for neuromuscular blockers?

Answer 8

Competitive antagonists that prevent endplate depolarisation

Question 9

What are presynaptic drugs that prevent ACh release?

Answer 9

Botox

Aminoglycosides

Question 10

What are the side effects of pyridostimine?

Answer 10

Stomach Pain
Nausea
Vomiting
Diarrhea;
Muscle cramps, twitching;
Sweating, increased salivation;
Cough with mucus;
Rash
Blurred vision.