IBD: Crohns and UC Flashcards
1
Q
How do you treat acute attacks of IBD?
A
Corticosteroids ie oral Prednisolone or Budesnide
2
Q
What are some side effects of taking corticosteroids
A
Skin thinning Moon face Acne Weight gain Mood swings
3
Q
What is used for moderate disease maintenance in IBD?
A
Aminosalicylates to reduce relaspe rates
4
Q
Name an aminosalicylate
A
Sulfasalazine
Mesalazine
5
Q
What are some side effects of aminosalicylates?
A
Nausea
Rashes
6
Q
If there is no response to primary treatment for IBD what is added?
A
Immunosuppression with Azothioprine or Methotrexate
7
Q
What is used in the treatment of severe Crohns
A
Infliximab (TBF alpha antibody)
8
Q
What are the side effects of azathioprine?
A
INFECTION RISK (particularly viral) and Diarrhoea. Rash. Fever. Tiredness. Muscle aches. Liver damage. Dizziness. Low BP