Asthma and anaphylaxis meds

Question 1

What causes the allergic response in Asthma?

Answer 1

IgE antibodies attach to mast cells causing degranulation and production and release of mediators (histamine)

Question 2

What are the ways the airways are affected in Asthma?

Answer 2

Narrowed by oedema (all the time)
Bronchospasm in attacks
Excessive mucus production

Question 3

Which aspect of the asthma attack causes the most damage?

Answer 3

Bronchial muscle spasm causes release of spasmogens (histamine, leucotrienes, prostaglandins) from mast cells. This causes chemotaxis of eosinophils causing vasodilation, oedema, mucous, bronchospasm which causes more damage than anything else

Question 4

What are the side effects of SABAs?

Answer 4

Fine Tremor

Tachycardia

Question 5

What kind of drug is Ipatropium?

Answer 5

Muscarinic Antagonist (decreases vagal bronchoconstriction)

Question 6

Name 2 inhaled steroids used in asthma

Answer 6

Beclometasone

Budesonide

Question 7

What kind of steroids are they?

Answer 7

Corticosteroids

Question 8

How long to steroids take to be effective?

Answer 8

3-7 days

Question 9

Name a LABA

Answer 9

Salmeterol