Autonomic NS Flashcards
Are the Cranial Nerves sympathetic or parasympathetic?
Parasympathic
Which CNs are part of the autonomic NS and how?
3- pupil constriction 7- tear secretion 9- salivary gland 10- Bronchoconstriction Bronchosecretion Gut Motility and tone Pancreatic secretion Micturition Defecation Erection
In the Sympathetic NS what are the 2 types of receptor? Are they inhibitory or excitatory?
Alpha- excitation
Beta- inhibition
What spinal level does the sympathetic NS come off at?
T1-L3
What things are affected by alpha sympathetic receptors?
Pupil dilation Thick saliva secretion Gut motility and tone Gluconeogenesis Adrenaline release Ejaculation Piloerection Contracts urinary sphincters
What kind of receptors are those in the sympathetic NS (postganglionic)
NORADRENERGIC
What are the parasympathetic receptors?
ACTYLCHOLINE in MUSCARINIC receptors
What are the receptors and neurotransmitter in preganglionic receptors in both sympa and parasympa
Ach in NICOTINIC receptors
What do beta 1 sympathetic receptors trigger?
Vasodilation
Intestinal smooth muscle relaxes
What do beta 2 sympathetic receptors trigger?
Increased heart rate and force
Bronchodilation
Glycogenolysis
Detrusor reflex
What are Muscarinic antagonists
Atropine (surgery)
Ipatropium (asthma)
Benzatropine (PD)
What are Muscarinic antagonists used for?
Limit secretions and maintain consistent heart rate during surgery
Parkinsons
To reduce intestinal spasm in IBS
Bronchodilator
What are sympathomimetics?
Sympathetic NS agonists (alpha and beta agonists)
What is Salbutamol?
Short acting Beta Agonist (B2) used in asthma to relax bronchi
B2 therefore has minimal impact on the heart
What is Dobutamine?
B1 agonist used to stimulate the heart in severe heart failure- speeds it up!
