Angina Flashcards
1
Q
How long does GTN spray work for?
A
30 mins
2
Q
Name a long acting Nitrate
A
Isosorbide Mononitrate
3
Q
How do Nitrates work?
A
NO is a vasodilator as muscle relaxes reducing end diastolic volume meaning that walls are less distended, reducing oxygen demand and therefore pain
4
Q
How to BBs work to relieve angina?
A
Decrease rate and force of contractions meaning that increased coronary artery perfusion between heart beats.
5
Q
What are BBs used for in angina?
A
Prophylaxis
6
Q
Why are CCBs used instead of BBs?
A
When BBs contraindicated ie vasospastic asthma
7
Q
Name 2 CCBs
A
Amlodipine
Nifedipine
8
Q
What are antiplatelet drugs used for in angina?
A
Erosion of plaques to reduce MI risk
9
Q
What is the mechanism of antiplatelet drugs and name one in each category?
A
GPIIb/IIIa blockade- Abciximab COX Inhibitor- Aspirin ADP receptor- Clopidogrel Thomboxane Inhibitor- Dipyridamole Heparin- binds to Antithrombin III
