Nausea, Vomiting, Gastroparesis Module (Quiz) Flashcards
how can peripheral signals irritate the GI tract
- directly
- stimulate peripheral afferent nerves to cause activation of regions of the CNS
sensory inputs such as pain, smell, and sight go to where area first
- high centers
inner ear motion goes where
- cerebellum
memory, fear, dread, and anticipation goes where
- higher centers
what is the chemoreceptor trigger zone
- area that receives signals from peripheral afferent nerves and toxins from blood stream
why can the chemoreceptor trigger zone receive toxins from the blood stream
- poor blood brain barrier
what center of the brain causes the events that lead to vomiting
- emetic center in the medulla
actions to induce retrograde expulsion of gastroduodenal contents
- contraction of diaphragm and abdominal muscles
- relaxation of lower esophageal sphincter
- anti-peralstaltic motion of duodenum
- contraction of stomach
how do we prevent aspiration during vomiting
- glottis and soft palate closed
- respiration stops
conditions to think about with acute nausea and vomiting
- infection
- toxin
- obstruction
- trauma
- pregnancy
conditions to think about for chronic nausea and vomiting
- motility disorder
- toxic medications
- endocrine or other GI diseases
- obstruction
- space occupying lesion near chemoreceptor trigger zone
what is gastroparesis
- lack of gastric motility or emptying in absence of obstruction
main etiology of gastroparesis
- diabetes
other etiologies of gastroparesis
- scleroderma
- drugs (opioids)
- idiopathi
symptoms of gastroparesis
- nausea/vomiting
- bloating
- epigastric pain
- weight loss