Embryology of Orofacial Structures Flashcards
orofacial and neck structures begin development during what weeks
4-8
what is another name for pharyngeal arch
- branchial arch
what are bulges called?
- arches
what are external invaginations between two arches
formed by
- clefts/grooves
- ectoderm
what are internal invaginations between two arches
formed by
- pouches
- endoderm
what is tissue separating cleft and pouch
- membrane
what are ventrolateral bulges in the area between the brain and thorax
- pharyngeal arches
how many pairs of pharyngeal arches
- 6
- the fifth disappears so 5
pharyngeal arches arise in which week of development
- 4
pharyngeal arches give rise to which parts of the body
- lower 2/3 of face
- oral cavity
- ear
- neck
external layer of pharyngeal arches derived from
- ectoderm
filling/core of pharyngeal arches derived from
which forms
- mesoderm - muscle, blood vessels
- neural crest - skeletal tissues
what does the neural crest have to do to get into the pharyngeal arches
what happens if it doesn’t do this
- migrate
- orofacial anomalies
internal lining (GI tract lining) of pharyngeal arch derived from
- endoderm
pharyngeal arch innervation by cranial nerves:
1 2 3 4 6
1 -> 5 2 -> 7 3 -> 9 4 -> 10 6 -> 10
face is derived from 5 ________ that meet at the ______-
- prominences/processes
- meet at the mouth
what is the mouth called early in development
- stomadeum
which processes make up the face
- frontonasal
- maxillary
- mandibular
maxillary and manidibular processes arise from which branchial arch
- branchial/pharyngeal arch 1
name for pharyngeal arch 1
- mandibular arch
what does pharyngeal arch 1 form
- lower 2/3 of face
pharyngeal arch 1 subdivides around the _________ to form the _______ and _________
- subdivides around oral cavity
- form upper/lower lip and jaws
maxillary process forms _______ of face
- mid 1/3 of face
mandibular process forms _______ of face
- lower 1/3 of face
skeletal derivatives of maxillary process
- upper jaw
skeletal derivates of mandibular process
begins as
- lower jaw, bones of ear
- Meckel cartilage
muscle derivates of pharyngeal arch 1
- muscles of mastication
- mylohyoid
- anterior belly digastric
- tensor tympani
- tensor veli palatini
how does the lower lip and jaw form
- from arch 1 mandibular processes fusing in midline
how does the upper lip and jaw form
- maxillary process of arch 1 with medial nasal processes
lip composed of
- middle 1/3 philtrum
- lateral 1/3
middle 1/3 philtrum of upper lip and jaw formed from
- frontonasal process
lateral 1/3 of upper lip and jaw formed from
- maxillary process
what cavities does the palate separate
- nasal and oral
3 areas fuse in a __ shape to form the palate
- Y-shape
track the processes that form the upper lip and jaw
- medial nasal -> median palatine -> primary palate
- maxillary -> lateral palatine -> secondary palate
the lateral palatine processes elevate from vertical to horizontal over the tongue around what weeks
- weeks 8-9
causes of cleft lip and palate
- genetic + teratogens
incomplete clefts mean
- partial lack of fusion
complete clefts mean
- total lack of fusion
cleft lip is ______ to incisive foramen
- anterior
clef palate is ______ to incisive foramen
- posterior
another name for pharyngeal arch 2
- hyoid arch
pharyngeal arch 2 starts with
- reichert cartilage
pharyngeal arch 2 skeletal derivatives
- hyoid
- stylohyoid ligament
- styloid
- stapes
muscle derivatives of pharyngeal arch 2
- muscles of fascial expression
- posterior belly digastric
- stylohyoid
- stapedius
skeletal derivatives of pharyngeal arch 3 starts with
- cartilage
skeletal derivatives of pharyngeal arch 3
- hyoid
muscle derivates of pharyngeal arch 3
- stylopharyngeus
skeletal derivatives of pharyngeal arches 4 and 6 start with
- cartilage
skeletal derivatives of pharyngeal arches 4 and 6
- laryngeal cartilages:
- thyroid
- cricoic
- arytenoids
- corniculate
- cuneiform
muscle derivates of pharyngeal arch 4
- pharyngeal constrictor group
- cricothyroid
- levator veli palatini
muscle derivates of pharyngeal arch 6
- all laryngeal except cricothyroid
pharyngeal arch 1 has which artery
- part of maxillary
pharyngeal arch 2 has which artery
- stapedial
pharyngeal arch 3 has which artery
- common carotid
- part of internal carotid
pharyngeal arch 4 has which artery
- right subclavian
- left arch of aorta
pharyngeal arch 6 has which artery
- pulmonary arteries
which pharyngeal arches contribute to parts of the tongue
- 1, 3, 4
arch 1 contributes to which portion of the tongue
- anterior 2/3
cranial nerve for touch/temp in anterior 2/3 of tongue is what
- 5
cranial nerve for taste in anterior 2/3 of tongue for taste is what
- 7
pharyngeal arch 3 contributes to what portion of the tongue
- Posterior 1/3
pharyngeal arch 4 contributes to what portion of the tongue
- base + epiglottis
muscles inside tongue are innervated by what cranial nerve
- 12
pharyngeal groove/cleft 1 will form the
- external acoustic meatus
what forms the smooth neck contour
- overgrowth of arch 2 covering up grooves 2-4
as overgrowth of arch 2 occurs, what is temporarily created
what happens if that fails to close
- cervical sinus
- branchial cleft cyst
pharyngeal pouch 1 forms
- eustachian tube
pharyngeal pouch 2 forms
- palatine tonsil
pharyngeal pouch 3 forms
- thymus
- inferior parathyroids
pharyngeal pouch 4 forms
- superior parathyroids
which pharyngeal pouches do not develop normally in DiGeorge syndrome
- 3 and 4
pharyngeal membrane 1 becomes what
- tympanic membrane
pharyngeal arch 1 and 2 forms what part of the ear
- auricle=pinna
what is the ear congenital anomaly that is a remnant from formation of auricle
- preauricular tag
what is the ear congenital anomaly that is small, malformed auricle
- microtia
fetal alcohol syndrome is especially important if fetus is exposed during what weeks of development
- 4-8