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1. Infection & Immunity > Mycoplasma + Chlamydia > Flashcards

Mycoplasma + Chlamydia Flashcards

1
Q

Mycoplasma belongs to the class_________

A

Mollicutes

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2
Q

Mycoplasma morphology

A

Smallest prokarys
Lack cell wall
Facultative anaerobes

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3
Q

Mycoplasma nutritional requirements

A

Limited biosynthetic potential (depend on host micoenvironment)
Exogenous fatty acids and sterols required

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4
Q

Mycoplasma growth

A

Require special media
Generation time of 1-6 hours
Fried egg appearance

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5
Q

Non-hemotropic mycoplasma

A

Most affect mucous membranes
Direct or indirect contact
Ex: Myco bronchopneumonia (M. bovis)

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6
Q

CS of non-hemotropic myoplasma

A

Respiratory and urogenital infections
Conjunctivitis, arthritis, mastitis, septicemia, otitis media

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7
Q

Hemotropic mycoplasma/ Hemoplasma

A

Transmitted by arthropods
Colonize RBCs (hemolysis)
Small, rod, on RBC surface

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8
Q

Hemotropic Mycoplasma CS

A

Hemolytic anemia, icterus, splenomegaly
Dx: Wrights, Giemsa, Diff-Qik

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9
Q

M. gallisepticum

A

Chronic resp. disease (CRD)
Most pathogenic avian myco.
Turkeys more susceptible
Swollen infraorbital sinuses

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10
Q

Chronic respiratory disease CS

A

Sinusitis, nasal discharge, coughing, sneezing, respiratory rales, conjunctivitis

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11
Q

M. synoviae

A

Upper resp. infection, airsacculitis, synovitis, green diarrhea and liver,
Subclinical/ carrier infections

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12
Q

M. meleagridis

A

Resp. disease in turkeys (via eggs)
Stunted growth, poor feathering and leg problem

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13
Q

M. iowae

A

Reduced hatchability, embryo mortality, resp. and leg problems in turkeys

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14
Q

How do you treat Mycoplasma in birds?

A

Macrolides: Erythromycin, azithromycin, tetracycline
Tylosin for meleagridis

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15
Q

Mycoplasma species in swine

A

M. hyopneumoniae, hyosynoviae, hyorhinis

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16
Q

M. hyopneumoniae

A

Porcine enzootic pneumonia
Economic problem worldwide
Damages airways cilia

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17
Q

M. hyosynoviae

A

Sporadic disease with polyarthritis in young animals 3-6 months

18
Q

M. hyorhinis

A

Sporadic polyserositis and polyarthritis in young animals
Indistinguishable from Glasser’s in pigs <3 months old

19
Q

M. bovis

A

Bronchopneumonia
Shipping fever and calf pneumonia
$32 million/yr for US

20
Q

CS of M. bovis

A

Arthtritis, keratovonjunctivitis, mastitis, abortions, otitis, abscess, oophoritis, genital infection

21
Q

Contagious agalactia

A

Small ruminants
Mastitis, arthritis, conjunctivitis
Causes by M. mycoides capri, capricolum capricolum

22
Q

Mycoplasma in cats and dogs

A

Oropharyngeal flora in cats
Upper resp, tracts of dogs
M. cynos: canine infectious resp. disease

23
Q

M. felis

A

Causes conjunctivitis and secondary pneumonia
Pathogen for pleuritis in horses

24
Q

What are the 4 common agents causing feline conjunctivitis

A

Feline herpes viris
Chlamydia
Mycoplasma
Calicivirus

25
Q

Mycoplasma pathogenesis

A

Interfere with host cell protein and ATP synthesis
Damage and loss of cilia in resp. tract
Buildup in cytotoxic metabolites and enzymes

26
Q

Mycoplasma diagnosis

A

PCR**
Skin scrape for cats (stain for IBs)
Culture (not practical)

27
Q

_____________ infection is the most widespread bacterial STD in the world and top reported disease to CDC

A

C. trachomatis

28
Q

Chlamydia general characteristics

A

Intracellular: grow in yolk sac and tissue culture, energy dependent
(energy parasites)
Cell wall visible by giemsa (DiffQuik)

29
Q

Elementary bodies of chlamydia

A

Infectious forms
Can survive in water for several days and dry environ for longer
Released by lysis

30
Q

Reticulate bodies of chlamydia

A

Larger, non-infectious intracellular forms
Metabolically active, can replicate

31
Q

Chlamydia life cycle

A

In vitro for 30-40 hrs

32
Q

Chlamydia is spread through ________

A

direct contact

33
Q

Chlamydia pathogenesis

A

Infects epithelial cells
Host macromolecule synthesis ceases
Cell autolysis
LPS and tissue damage initiates inflammatory rx

34
Q

Psittacosis/ orinthosis (parrot fever)

A

Chlamydial disease (notifiable)
Category B agent
Caused by C. psittaci
Occupational disease

35
Q

Psittacosis susceptibility

A

Pigeons develop a subclin disease
Turkeys more sensitive
50-80% morbidity

36
Q

Psittacosis CS

A

Fever, anorexia, conjunctivitis, yellow-green gelatinous droppings
Drop in egg production
Pneumonitis, arthritis

37
Q

Psittacosis transmission

A

Inhalation of aerosolized bacteria from droppings, feathers or tissues, urine, saliva, feces, etc.

38
Q

Chlamydial abortion

A

In women, cattle, sheep, pigs and horses
Casues by C. abortus
Late pregnancy abortions and retained placenta

39
Q

C. felis

A

In cats causes acute, chronic or recurrent conjunctivitis
< 1 yr old
IBs

40
Q

Chlamydia diagnosis

A

IBs show in cytology/ staining
PCR
Tissue culture
IFAT (immunofluorescent Ab test)

41
Q

Chlamydia sensitivity

A

Doxycycline (act on protein synthesis)
Quaternary ammonium compounds and chlorphenol, 1% bleach disinfectants

1. Infection & Immunity (19 decks)

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