Muscles And Movement Flashcards
Muscle
Specialized for movement; facilitate motion via contraction pairs (tense vs relaxed)
How are muscle tissue hierarchically arranged?
Muscle -> fascicle -> sarcolemma -> myofiber -> myofibril -> sarcomere
Sarcomere
Basic unit of muscle contraction
Thick filaments
Thick braid of myosin
Thin filaments
Thin braid of actin
Which line moves during muscle contraction? Z line or M line?
Z line
Sliding filament theory
Muscles contract when sarcomere shorten; actin moves and overlaps w/ one another and myosin doesn’t move; doesn’t change lengths
Cross bridge cycle
Shortens the sarcomere
- ATP binds to myosin head
- Myosin head changes shape and hydrolysis the ATP into ADP + phosphate
- Myosin head binds to actin and creates a cross bridge (still w/ ADP and phosphate)
- ADP and phosphate group is released during power stroke (moving actin/pushing thin filament)
ADP and phosphate only unbinds when there is another ATP ready to bind to myosin
After death, the body enters rigor mortis-a state where all muscles contract and the body tensed up. What step of the cross bridge cycle must the sarcomere be in during rigor mortis?
Step 4 (body is dead meaning no ATP production)
Motor units
Control a number of muscle fibers to contract
How does calcium release affect cross bridge cycle?
Action potentials from motor neurons open voltage gated Ca channels in the sarcoplasmic reticulum. The SR releases Ca and the Ca binds to troponin on the tropomyosin. This allows myosin to freely bind to actin and start the cross bridge cycle, which shortens the sarcomere and causing muscle contractions and movement.
Troponin
Ca binds to it to expose myosin binding sites
Tropomyosin
Stops myosin from binding to actin
Sarcoplasmic reticulum
Highly modified ER for the muscle; contains a lot of Ca
Transverse tubules
Extends into the cell and touches SR and transfers action potentials to open Ca channels in the SR