MSK path XII

Question 1

skeltal mm neoplasms

bengn or malignant

Answer 1

almost always malignant

Question 2

subtypes of rhabdomyosarcoma

Answer 2

alveolar, embryonal and pleomorphic

Question 3

msot common soft tissue sarcoma of childhood and adolescence

Answer 3

rhabdomyosarcoma

Question 4

what rhabdo is seen in adults

Answer 4

pleomorphic

Question 5

presentation of childhood rhabdos

Answer 5

sinuses, head and neck and GU tract

Question 6

sarcoma botryoides

Answer 6

rhabdo in vagina

looks like cluster of grapes

Question 7

visible cross striations and sheets of primitive round and spindled cell sin myxoid stroma

Answer 7

rhabdo

Question 8

Tx rhabdos

Answer 8

surgery an chemo +/- radiation

Question 9

which rhabdo has best prognosis

Answer 9

boytroid embryonal

Question 10

msot common benign tumor in women

Answer 10

leiomyomas

Question 11

bleeding out of pyloric sphincter, looks like volcano

Answer 11

GIST tumor

ckit +

Question 12

pilar leiomyomas

Answer 12

leiomyomas that arise in skin, nipples, scrotum and labia

sometimes muscularis of gut

Question 13

where do leiomyosarcomas arise

Answer 13

deep soft tissues of extremities and retroperitoneum

Question 14

painless firm mass in retroperitoneum

eosinophilic spindle cells with blunt ended hyperchromatic nuclei arranged in interweaving fascicles

Answer 14

leiomyosarcomas

Question 15

ab staining for leiomyosarcomas

Answer 15

Ab to smooth mm actin and desmin

Question 16

where does leiomyosarcoma mets to

Answer 16

lungs

Question 17

Carcinoma with biphasic area suggesting sarcoma

aspirate in knee

Answer 17

synovial sarcoma

Question 18

presentation synovial sarcomas

Answer 18

20s 40s

deep seated mass that has been present for several years

Question 19

what are epithelial markers for synovial sarcoma

Answer 19

keratins

Question 20

Tx synovial sarcoma

Answer 20

surgery and chemo

Question 21

mets of synovial sarcoma

Answer 21

lungs and regional lymph nodes

Question 22

what is new name for malignant fibrous histiocytoma

Answer 22

pleomorphic sarcoma

Question 23

fascicles of spindle cells in a storiform pattern (pinwheel)

Answer 23

pleomorphic sarcoma

Question 24

herringbone pattern

Answer 24

fibrosarcoma

Question 25

largest category of adult sarcomas

Answer 25

undifferentiated pleomorphic sarcoma

Question 26

where do most pleomorphic sarcomas arise

Answer 26

in the deep soft tissues of extremity

Question 27

coagulative necrosis is seen in what tumors

Answer 27

fibrosarcomas- pleomporphic