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Year2 MSK exam 1 > MSK path XI > Flashcards

MSK path XI Flashcards

1
Q

ganglions synovial cysts and osteochondral loose bodies form from what

A

trauma or degenerative processes

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2
Q

what is a ganglion

A

1-1.5 cm cyst usually near joint capsule or tendon sheath

usually around wrist

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3
Q

what causes ganglion cyst

A

cystic or myxoid degeneration of CT

lacks cell lining

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4
Q

do ganglion cysts communicate with joint space

A

no

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5
Q

what can cause synovial cyst

A

herniation of synovium though joint capsule or massive enlargement of bursa

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6
Q

what is a baker cyst

A

synovial cyst in popliteal space in RA

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7
Q

synovial lining in synovial vyst

A

hyperplastic and contain inflammatory cells and fibrin

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8
Q

what do ganglion and synovial cysts feel like

A

soft squishy

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9
Q

what is a tenosynovial giant cell tumor

A

closely related benign neoplasms that develop in synovial lining of joints, tendon sheaths and bursae

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10
Q

clinical variants tenosynovial giant cell tumors

A

diffuse type- pigmented villonodular synovitis)

localized type- giant cell tumor of tendon sheath

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11
Q

diffuse tenosynovial giant cell tumors form where

A

large joints

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12
Q

localized type tenosynovial giant cell form where

A

discrete nodule attached to tendon sheat (commonly the hand)

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13
Q

Dx age for tenosynovial giant cell tumors

A

20-40s

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14
Q

color diffuse tenosynovial giant cell tumors

A

red brown, orange yellow
red brown stripes or folds “tiger stripe”
infiltrate subsynovial tissue

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15
Q

localized type tenosynovial giant cell shape

A

well circumscribed

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16
Q

diffuse type tenosynovial giant cell type presents where

A

knee then hip, ankle, and calcaneocuboid joints

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17
Q

Sx diffuse type tenosynovial giant cell

A

pain, locking and recurrent swelling similar to monoarticular arthritis

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18
Q

what limits ROM in joint in tenosynovial giant cell tumors

A

tumor progression

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19
Q

characteristics of localized type tenosynovial giant cell tumor

A

solitary, slow growing, painless

usually tendon sheaths on wrists and fingers

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20
Q

most common mesenchymal neoplasm of hand

A

localized type tenosynovial giant cell

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21
Q

tenosynovial giant cell tumors are Tx how

A

surgical excision

22
Q

what drugs are used in tenosynovial giant cell tumors

A

M CSF antagonists b/c block proliferation of giant cells

23
Q

what is soft tissue

A

non epithelial excluding skeleton, joints, CNS, hematopoietic and lymphoid tissues

24
Q

what are more common benign or malignant soft tissue neoplasms

A

benign all the way

25
Q

most soft tissue tumors arise where

A

thigh

26
Q

what is big determinant for soft tissue tumor benign vs malignant

A

above or below fascial plane

27
Q

what translocation for ewing sarcoma

A

t11;22

28
Q

soft tissue tumor with eosinphilic spindle cells at 90 angles

A

smooth muscle type

29
Q

soft tissue tumor with short fascicles of spindle cells like spokes on a wheel

A

fibrohistiocytic

30
Q

soft tissue tumor arranged in columns, palisading

A

schwann cell

31
Q

what is characteristic of schwannoma

A

antoni A and B

32
Q

soft tissue tumor with herringbone

A

fibrosarcoma

33
Q

soft tissue tumor with mixture fascicles of spindle cells and groups epithelioid cells biphasic

A

synovial sarcoma

34
Q

important prognostic factors in soft tissue tumors

A

muscle differentiation, degree of differentiation, size and depth

35
Q

what looks like chinese characters on histo

A

fibrodysplasia

36
Q

what is a benign tumor of fat and most common soft tissue tumor of adulthood

A

lipoma

37
Q

what are liposarcomas

A

50s-60s in deep soft tissues in proximal extremities and retroperitoneum

38
Q

subtypes liposarcomas

A

well differentiated
myxoid (basophilic extracellular matrix and capillaries, fetal fat looking like stuff)
pleomorphic- sheets anaplastic cells, bizarre nuclei and lots of immature adipocytes

39
Q

what color is the myxoid type liposarcoma

A

gray

40
Q

what is nodular fascitis

A

self limited fibroblastic and myofibroblastic proliferation that typically occurs in young adults of upper extremity

41
Q

what is always present in Hx for nodular fascitis

A

history of trauma

42
Q

5 cm lesion circumscribed, rich cellularity with immature fibroblasts and myofibroblasts in short fascicles
cells vary in shape with conspicuous nucleoli
lots of mitoses
lymphocytes and RBC common

A

nodular fascitis

43
Q

dupetryns contraction is an example of what

A

fibromatoses

44
Q

what is pink stuff in fibromatoses

A

fibrocollagen

45
Q

superficial fibromatosis

A

infiltrative fibroblastic proliferation

broad fascicles of fibroblasts in long sweeping fascilces with dense collagen

46
Q

what is most comon types of fibromatoses superficial

A

palmar and plantar

47
Q

what is peyronie disease

A

penile superficial fibromatoses

48
Q

what are desmoid tumors

A

deep fibromatosis

recur but no metastasis

49
Q

when do deep fibromatosis present

A

teens-30s and F>M (weird)

50
Q

types of deep seated fibromatosis

A

extraabdominal, abdominal and intraabdominal

51
Q

when do you see the extraabdominal deep fibromatosis

A

W with many babies and C csection scarring

52
Q

gray white firm poorly demarcated mass 1-15 cm
rubbery tough with infiltraiton of muscle nerve and fat
bland fibroblasts in borad sweeping fascicles

A

fibromatoses

Year2 MSK exam 1 (26 decks)

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