MSK path VI

Question 1

can lead to pyogenic osteomyelitis

Answer 1

hematogenous spread
extension from a contiguous site
direct implantation

Question 2

what microbe is majority of pyogenic osteomyelitis

Answer 2

staph aureus

Question 3

what is microbe that can cause pyogenic osteomyelitis in sickle cell patient

Answer 3

salmonella because needs good C’ working to kill it

Question 4

what is clearing dot on staph aureus culture

Answer 4

methicillin

Question 5

child has subperiosteal abscess, suspect what

Answer 5

pyogenic osteomyeltiis

Question 6

what is sequestrum

Answer 6

dead bone

Question 7

brodie abscess

Answer 7

small intraosseous abscess that involves Cx and walled off by reactive bone

Question 8

what is name of reactive bone that walls of pyogenic osteomyeltiis infection

Answer 8

involucrum

Question 9

osteonecrosis of jaw

Answer 9

sclerosing osteomyelitis of Garre

Question 10

what occurs if see sinus tract in skin oozing thick fluid looks like from bone

Answer 10

chronic pyogenic osteomyelitis

Question 11

malaise fever, chills, leukocytosis, and throbbing pain over bone

Answer 11

hematogenous osteomyelitis

Question 12

Dx osteomyeltisi

Answer 12

radiographic finding of lytic lesion surrounded by zone of sclerosis

Question 13

what is required to identify pathogen in myelitis

Answer 13

Bx and bone cultures even if sample blood culture +

Question 14

Tx osteomyelitis

Answer 14

antibiotics and surgical drainage

Question 15

What is mycobacterial osteomyeltis

Answer 15

TB spondylitis (Pott disease)
destructive

Question 16

benign bone tumors Dx how

Answer 16

incidental finding

Question 17

first hint of bone tumor usually

Answer 17

pathologic tumor

Question 18

needed to definitively Dx bone tumor

Answer 18

bone Bx

Question 19

window where bone tumor likely benign

Answer 19

1-30 y.o

Question 20

most common primary cancer of bone

Answer 20

osteosarcoma

Question 21

what are the malignant bone tumors

Answer 21

myeloma and lymphoma

hematopoietic spread

Question 22

what are the benign cartilage forming tumors

Answer 22

osteochondroma
chondroma
chondroblastoma
chondromyxoid fibroma

Question 23

what are the malignant cartilage forming tumors

Answer 23

chondrosarcoma

Question 24

chondroblastomas involve what part of bone

Answer 24

epiphysis of long bones

Question 25

chondromas affect what bones

Answer 25

small bones of hands and eet

Question 26

osteochondroma affect what part of bones

Answer 26

metaphysis long bones

Question 27

myelomas and lymphomas attack what bones

Answer 27

vertebrae and pelvis

Question 28

difference of osteoid osteoma and osteoblastoma

Answer 28

size, sites of origin and Sx

Question 29

what do osteoid osteomas and osteoblastomas look like grossly

Answer 29

round oval masses of gritty hemorrhagic tan tissue

Question 30

rim of osteoid osteomas and osteoblastomas

Answer 30

single layer osteoblasts

Question 31

what encircles osteoid osteoma lesion

Answer 31

lots of reactive bone

Question 32

what is the center of osteoid osteoma called

Answer 32

nidus

Question 33

what do cells of osteosarcoma produce

Answer 33

osteoid matrix or mineralized bone

Question 34

most common primary malignant tumor of bone

Answer 34

osteosarcoma

Question 35

peaks of osteosarcoma

Answer 35

<20 y.o

older adults

Question 36

what is assoc with older age onset osteosarcoma

Answer 36

have pagets or bone infarcts or prior radiation

Question 37

where fo osteosarcoma arise

Answer 37

long bones
metaphysis
50% around knee

Question 38

presentation osteosarcoma

Answer 38

painful, progressively enlarging masses

can have sudden fracture

Question 39

radiographs of osteosarcoma

Answer 39

large destructive mixed lytic and blastic mass with infiltrative margins

Question 40

codman triangle

Answer 40

between Cs and periosteum

indicates aggressive tumor

Question 41

distal lytic lesion in bone <20 y.o

Answer 41

osteosarcoma until proven otherwise

Question 42

where o osteosarcomas mets

Answer 42

lungs

Question 43

sites of osteosarcomas

Answer 43

intramedullary, intracortical or surface

Question 44

most common subtype osteosarcoma

Answer 44

primary intramedullary, osteoblastic and high grade

Question 45

color of osteosarcoma

Answer 45

tan white with areas of hemorrhage and cystic degeneration

Question 46

pink stuff in aspirate of osteosarcoma

Answer 46

osteoid

Question 47

prognosis osteosarcoma

Answer 47

if no mets 5 yr 60-70%

if mets <20% 5 yr