Derm path DSA Flashcards

1
Q

major functions of skin

A

protective covering
tactile interaction
body temp regulation

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2
Q

how does skin fucntion as part of immune system

A

production of cytokines and defensins

Ag presentation via Langerhans Epidermal Dendritic Cells and possibly dermal dendrocytes

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3
Q

organization of skin

A

epidermis
dermis
subcutis

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4
Q

what are the 2 types of dermis

A

papillary dermis and reticular dermis

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5
Q

what are the adnexal structural units of the skin

A

pilar (hair) units
eccrine units
apocrine units

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6
Q

what are the pilar units of skin

A

pilosebaceous units, arrector pili muscles

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7
Q

what are the eccrine units of skin

A

eccrine glands and ducts

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8
Q

what are the apocrine unites of skin

A

apocrine glands and ducts

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9
Q

where is papillary dermis

A

right beneath the dermal epidermal jucntion

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10
Q

what are the stratums of skin in order from most superficial to deep

A
stratum corneum
stratum lucidum
stratum granulosum
stratum spinosum
stratum basale
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11
Q

what is a sebaceous gland

A

oil gland

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12
Q

what is an eccrine gland

A

sweat gland

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13
Q

where are the apocrine glands located

A

deep dermis and often at junction of reticular dermis and subcutanous tissue

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14
Q

what are melanocytes

A

supply keratinocytes with melanosomes

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15
Q

what are the intercellular bridges between squamous cells

A

desmosomes

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16
Q

what makes up the papillary dermis

A

type I collagen, parallel to surface
some type III and network of elastic fiber
healing by secondary intention
capillaries of superficial plexus (blushing and sunburn)

17
Q

what blistering immune diseases invade BM

A

bullous pemphigoid
dermatitis herpetiformis
epidermolysis bullosa

18
Q

what is a pacinian corpuscle

A

encapsulated nerve ending
pressure R
found in deep dermis or hypodermis

19
Q

what is a meissner corpuscle

A

touch R
confined to dermal papillae
most numerous on hands and feet

20
Q

what type of nerves detect pain and temp

A

free nerve endings from sympathetic nervous system that controls blood flow and hair movement

21
Q

what makes up the hypodermis

A

loose and dense CT
adipocytes arranged in lobules
fibroconnective tissue arranged in septae

22
Q

pancreatitis has what type panniculitis

23
Q

erythema nodosum has what type panniculitis

A

erythema nodosum

24
Q

hypodermis connects what

A

reticular dermis with fascia of underlying tissue

25
roles of hypodermis (subcut)
body temp regulation (adipose) primary depot for fat storage (large energy reserve) aging most evident in this layer
26
what are wrinkles
basal layer proliferation decreased melanocytes decrease langerhans thinning of ground substance
27
what happens to hair follicles with age
decreased hair shaft diameter | decreased number hair follicles (decreased oil production leading to xerosis or dry skin)
28
what is solar elastosis
actinic degeneration of reticular dermis collagen
29
what is telangiectasia
small dilated blood vessels
30
what are the changes in dermis associated with sunburn
increased blood flow | superficial blood vessels show endothelial swelling, perivenular edema, mixed perivascular inflammatory infiltrate